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AT3G12980.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : histone acetyltransferase of the CBP family 5
Curator
Summary (TAIR10)
Encodes an enzyme with histone acetyltransferase activity that can use both H3 and H4 histones as substrates. No single prior lysine acetylation is sufficient to block HAC5 acetylation of the H3 or H4 peptides, suggesting that HAC5 can acetylate any of several lysines present in the peptides. Di-acetylation of both lysines 9 and 14 on the H3 peptide significantly reduces the level of incorporated radioactive acetylation catalyzed by HAC5, indicating that HAC5 may acetylate either lysine 9 or lysine 14.
Computational
Description (TAIR10)
histone acetyltransferase of the CBP family 5 (HAC5); FUNCTIONS IN: histone acetyltransferase activity; INVOLVED IN: flower development, protein amino acid acetylation; LOCATED IN: nucleus; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Histone H3-K56 acetyltransferase, RTT109 (InterPro:IPR013178), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, TAZ-type (InterPro:IPR000197), Zinc finger, PHD-type (InterPro:IPR001965), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, ZZ-type (InterPro:IPR000433); BEST Arabidopsis thaliana protein match is: histone acetyltransferase of the CBP family 1 (TAIR:AT1G79000.1); Has 1382 Blast hits to 1050 proteins in 154 species: Archae - 0; Bacteria - 14; Metazoa - 567; Fungi - 56; Plants - 349; Viruses - 4; Other Eukaryotes - 392 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G12980-MONOMERBioGrid:5818EC:2.3.1.48eggNOG:ENOG410IRV8
eggNOG:ENOG4111K0HEMBL:AB026645EMBL:AF512557EMBL:AF512558
EMBL:CP002686EnsemblPlants:AT3G12980EnsemblPlants:AT3G12980.1entrez:820484
Gene3D:1.20.1020.10Gene3D:3.30.40.10GeneID:820484Genevisible:Q9LE42
GO:GO:0003712GO:GO:0004402GO:GO:0005634GO:GO:0006351
GO:GO:0006355GO:GO:0006473GO:GO:0008270GO:GO:0009908
Gramene:AT3G12980.1hmmpanther:PTHR13808HOGENOM:HOG000242057InParanoid:Q9LE42
InterPro:IPR000197InterPro:IPR000433InterPro:IPR011011InterPro:IPR013083
InterPro:IPR013178InterPro:IPR019786InterPro:IPR031162iPTMnet:Q9LE42
KEGG:ath:AT3G12980KO:K04498MINT:MINT-8069366ncoils:Coil
OMA:EDNCESKPaxDb:Q9LE42Pfam:PF00569Pfam:PF02135
Pfam:PF08214Pfam:Q9LE42Pfscan:PS50134Pfscan:PS50135
Pfscan:PS51727PhylomeDB:Q9LE42PRIDE:Q9LE42PRO:PR:Q9LE42
PROSITE:PS00028PROSITE:PS01357PROSITE:PS01359PROSITE:PS50134
PROSITE:PS50135PROSITE:PS51727ProteinModelPortal:Q9LE42Proteomes:UP000006548
Reactome:R-ATH-3371568Reactome:R-ATH-6781823Reactome:R-ATH-6782135Reactome:R-ATH-6782210
RefSeq:NP_187904.1scanprosite:PS01357scanprosite:PS01359SMART:SM00291
SMART:SM00551SMART:SM01250SMR:Q9LE42STRING:3702.AT3G12980.1
SUPFAM:SSF57850SUPFAM:SSF57903SUPFAM:SSF57933TAIR:AT3G12980
tair10-symbols:ATHPCAT4tair10-symbols:HAC5UniGene:At.39511UniProt:Q9LE42
Coordinates (TAIR10) chr3:+:4146919..4154495
Molecular Weight (calculated) 188198.00 Da
IEP (calculated) 8.56
GRAVY (calculated) -0.65
Length 1670 amino acids
Sequence (TAIR10)
(BLAST)
0001: MAQGQNRTVL QSGQMHNSVV ASASSVSSQP NMVNGISQDT LLLRQEMLNR TYAWLQQRQP SKTDDASKAK LSEVAKRLES AMWRTATSKE DYLDFRSFDV
0101: RVESTLKQLL SQRRANPSSS VSTMVQTPGV SHGWGQSYTA TPMVDTSKFN SSNNLSDATT ETGRLLPTNR MYRGTINNGR QELSAVGQMI PTPGFDNSAN
0201: ADVYQSHRNE EYSGDGGKLL ATGSDFGNPS QLQKQRPTGS NDLMGYNLDH QLGGGFRSNI HQNTSGMTSI PLNAGVGMSG NNVHLANVPR SSEGVLSSTH
0301: FSTFSQPSQQ PVEQLQVSHV NRYSMSNSGT FVSGNLYGVQ TSSGSIETAV DMNSMSLNSM RRVDTSFGSQ SGLQNNPLLK PHLRHQFENG NFQSSSNSKE
0401: NLAQVSHRPL ERQFNQQAHY GQYHQQELLM NNDAYRQSQP ASNLVSQVKN EPRVEYYNEA FQMQAINKVE PSKPQNQYKQ NTVKDEYVGA QSAPVSSSQL
0501: KMSPSFPPQT HQTQQVSQWK DSSSLSAGVQ PVSGLGQWHS SSQNLTPISK NSNEEREHFG VRFHKQHEGT NNSSSVREST NCLTVAPSGT LDVPHLPVGI
0601: NVLSKQLNGD CGLSYKNQRR WLLFLLHVRK CNAAEDNCES KYCFTAKTLL KHINCCKAPA CAYQYCHQTR QLIHHYKHCG DEACPVCVFV KNFKEKQKEK
0701: FTFLQRAEPS SASLNHGPKE SFESMRTSSE RDSEAPFVVD DLQPSPKRQK VEKPSQFAYP DTQGNPATIS AGVSQAHFSM GLQEKDRLPS DVCKPVRSNV
0801: PMNADSSDSS RRLVPVSREL EKPVCKDTHM GRHGVKSALD GESLRLSKQE KPKRMNEISA PKEENAEQSL GVVSASNCGK SKIKGVSLIE LFTPEQVEEH
0901: IRGLRQWVGQ SKTKAEKNKA MGLSMSENSC QLCAVERLAF EPTPIYCTPC GARVKRNAMH YTVVAGESRH YVCIPCYNEA RANTVSVDGT PVPKSRFEKK
1001: KNDEEVEESW VQCDKCQAWQ HQICALFNGR RNHGQAEYTC PNCYIQEVEQ GERKPVSQNV ILGAKSLPAS TLSNHLEQRL FKKLKQERQE RARLQGKSYE
1101: EVPGADSLVI RVVASVDKIL EVKPRFLDIF REDNYSSEFP YKSKAILLFQ KIEGVEVCLF GMYVQEFGTD SASPNQRRVY LSYLDSVKYF RPDVRTVSGE
1201: ALRTFVYHEI LIGYLDYCKK RGFSSCYIWA CPPLKGEDYI LYCHPEIQKT PKTDKLREWY LAMLKKASKE KVVVECTNFY DHFFVQSGEC RAKVTAARLP
1301: YFDGDYWPGA AEDLIDQMSQ EEDGKKSNRK LMPKKVISKR ALKAVGQLDL SVNASKDLLL MHKLGEIILP MKEDFIMVHL QHCCKHCCTL MVSGNRWVCN
1401: QCKNFQICDK CHEVEENRVE KEKHPVNQKE KHVLYPVAID NIPTEIKDND DILESEFFDT RQAFLSLCQG NHYQYDTLRR AKHSSMMILY HLHNPTVPAF
1501: AMACAICQQE LETAQGWRCE VCPDYDVCNA CYSKGINHPH SIISRPSATD SVVQNTQTNQ IQNAQLREVL LHVMTCCTAQ CQYPRCRVIK GLIRHGLVCK
1601: TRGCIACKKM WSLFRLHSRN CRDPQCKVPK CRELRAHFSR KQQQADSRRR AAVMEMVRQR AADTTASTPE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)