AT2G44110.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 1.000 ASURE: plasma membrane What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Seven transmembrane MLO family protein | ||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO15 belongs to the clade II, with ATMLO13 and ATMLO15. The gene is expressed during early seedling growth, in root tips and flower (papillae, anthers and pollen grains), as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). | ||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
MILDEW RESISTANCE LOCUS O 15 (MLO15); FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: integral to membrane; EXPRESSED IN: male gametophyte, root tip, root, papillae; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT4G02600.2); Has 552 Blast hits to 534 proteins in 57 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 548; Viruses - 0; Other Eukaryotes - 4 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr2:-:18245489..18248316 | ||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 56154.00 Da | ||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 9.40 | ||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | 0.24 | ||||||||||||||||||||||||||||||||||||||||
| Length | 496 amino acids | ||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MAGGGTTLEY TPTWVVALVC SVIVSISFAV ERLIHRAGKH FKNNDQKQLF GALQKIKEEL MLVGFISLLL SVGQSKIAKI CISKELSEKF LPCTKPAGAE 101: KSLKDSSHFQ FSFTGRHLLA GDAPAGDYCS LKGKVPIMSL SALHELHIFI FVLAVAHIIF CLLTIVFGTM KIKQWKKWED KVLEKDFDTD QSIKKFTHVQ 201: EHEFIRSRFL GVGKADASLG WVQSFMKQFL ASVNESDYIT MRLGFVTTHC KTNPKFNFHK YLMRALNSDF KKVVGISWYL WVFVVLFLLL NIVAWHVYFW 301: LAFIPLILLL AVGTKLEHII TDLAHEVAEK HIAVEGDLVV RPSDDLFWFQ SPRLVLFLIH FILFQNSFEI AYFFFILFQF GWDSCIMDHV KFVIPRLVIG 401: VIIQLLCSYS TLPLYALVTQ MGSSFKGAIF NEQTQEHLVG WAKMAKRGVK KGATQVGTSH DATSPRPSIQ LNSLLGKGSS QQNQNPKEKS EIAHHD |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)