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AT2G39810.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:30961429 (2019): nucleus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
  • PMID:22550958 (2012): plastid
  • PMID:21433285 (2011): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : ubiquitin-protein ligases
Curator
Summary (TAIR10)
A novel protein with a RING finger motif near the amino terminus. Negative regulator of cold responses. Functions as an E3 ligase required for the ubiquitination of ICE1. HOS1 physically interacts with ICE1 and mediates the ubiquitination of ICE1 both in vitro and in vivo. Overexpression represses the expression of CBFs and their downstream genes and confers increased sensitivity to freezing stress.
Computational
Description (TAIR10)
HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1 (HOS1); FUNCTIONS IN: ubiquitin-protein ligase activity; INVOLVED IN: response to cold, negative regulation of transcription, protein ubiquitination; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 12 growth stages; Has 239 Blast hits to 237 proteins in 68 species: Archae - 0; Bacteria - 0; Metazoa - 131; Fungi - 0; Plants - 80; Viruses - 5; Other Eukaryotes - 23 (source: NCBI BLink).
Protein Annotations
BioGrid:3906DIP:DIP-61174NEC:6.3.2.-eggNOG:ENOG410IF8D
eggNOG:ENOG4110YTDEMBL:AC003000EMBL:BT004255EMBL:BT005517
EMBL:CP002685EnsemblPlants:AT2G39810EnsemblPlants:AT2G39810.1entrez:818568
GeneID:818568Genevisible:Q84JU6GO:GO:0004842GO:GO:0005634
GO:GO:0005737GO:GO:0009409GO:GO:0009966GO:GO:0010228
GO:GO:0016567GO:GO:0016874GO:GO:0045892GO:GO:0046872
Gramene:AT2G39810.1hmmpanther:PTHR10044hmmpanther:PTHR10044:SF129HOGENOM:HOG000083689
InParanoid:Q84JU6InterPro:IPR025151iPTMnet:Q84JU6KEGG:ath:AT2G39810
KO:K16278OMA:RLYYECVPaxDb:Q84JU6Pfam:PF13934
Pfam:Q84JU6PhylomeDB:Q84JU6PIR:T01011PRIDE:Q84JU6
PRO:PR:Q84JU6ProteinModelPortal:Q84JU6Proteomes:UP000006548RefSeq:NP_181511.3
SMR:Q84JU6STRING:3702.AT2G39810.1TAIR:AT2G39810tair10-symbols:HOS1
UniGene:At.37128UniPathway:UPA00143UniProt:Q84JU6
Coordinates (TAIR10) chr2:+:16612941..16617802
Molecular Weight (calculated) 105235.00 Da
IEP (calculated) 5.39
GRAVY (calculated) -0.47
Length 927 amino acids
Sequence (TAIR10)
(BLAST)
001: MDTREINGFA SAARSISLPT QPNYSSKPVQ EALKHLASIN LRELCNEAKV ERCRATRDLA SCGRFVNYVL NPCGHASLCT ECCQRCDVCP ICRSTLPKFG
101: DRLRLRLYYE CVEAGLISRT HEEASQDSDE DEHQLAADVH RLYSLFDVAM NNNLISVVCH YITNVCMDET AVSSDPVIAF LLDEVVVKDW VKRTFRSTLA
201: ELQEIYNLET KEMQAWLDKL LRCSKQVAGI CSVLEVMESA FKGSVSPQLQ DVQTLRENIG KTKQHLDIMV WCIRHGFLDD VRSRYSNFTS WNALVGERKS
301: NAVKRAWPDA VDQSSDCSVQ SASLFIEDAL ENLEREPEYS QEIGADLEVG RLQKDKRSFL RSKIEGTSGS YPFENLRTAA DMLFLHGGSD LVVAKQAIFL
401: YYLFDRHWTT PEKYWKHTID DFAATFGITR HSLLESFVFY LLDDHSEEAL QEACRILPEI CGPETYPKVA QVLLERDNPE TALMVLRWSG RDGVSELVSI
501: GEAVTALRVR VECGLLSEAF TYQRTLCLKV KENNLKNGAV KHASDDLDIW SWTEWMEILV NEFCCLSIRR NLVDRIIELP WNPDEEKYLH RCLLDSATDD
601: PSSAVGSLLV VFYLQRYRYI QAYQVDLRLQ KIEEAFVSDN QIGEEVMFRM RSQSHWRKEL VDRAIDILPV IQQQQVRSGQ FSEMEDASEG AKKSDLPDAP
701: DMITSSVPFA TTNSVFLQSA NNARAREPVA NNGSPFQPGH MIGNASHDLS HGRLFTNANR GQKSEVRSVT KNLKFGEMST PFKDLNRARG NSQLQGKRTE
801: ESSPEVNVDR YIENNMSSPY LRRITANNPV TVKSSSNHLN GSSQKPESTF FGTRMQPDKD NFVDLDDPMD MSSSLKDNNN NVLATESRNN SGGLRWRSDE
901: TSDDEDELTS FGSMPVKGRR RRRFAAR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)