AT2G39810.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:nucleus 1.000 What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : ubiquitin-protein ligases | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
A novel protein with a RING finger motif near the amino terminus. Negative regulator of cold responses. Functions as an E3 ligase required for the ubiquitination of ICE1. HOS1 physically interacts with ICE1 and mediates the ubiquitination of ICE1 both in vitro and in vivo. Overexpression represses the expression of CBFs and their downstream genes and confers increased sensitivity to freezing stress. | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1 (HOS1); FUNCTIONS IN: ubiquitin-protein ligase activity; INVOLVED IN: response to cold, negative regulation of transcription, protein ubiquitination; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 12 growth stages; Has 239 Blast hits to 237 proteins in 68 species: Archae - 0; Bacteria - 0; Metazoa - 131; Fungi - 0; Plants - 80; Viruses - 5; Other Eukaryotes - 23 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr2:+:16612941..16617802 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 105235.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 5.39 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.47 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 927 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MDTREINGFA SAARSISLPT QPNYSSKPVQ EALKHLASIN LRELCNEAKV ERCRATRDLA SCGRFVNYVL NPCGHASLCT ECCQRCDVCP ICRSTLPKFG 101: DRLRLRLYYE CVEAGLISRT HEEASQDSDE DEHQLAADVH RLYSLFDVAM NNNLISVVCH YITNVCMDET AVSSDPVIAF LLDEVVVKDW VKRTFRSTLA 201: ELQEIYNLET KEMQAWLDKL LRCSKQVAGI CSVLEVMESA FKGSVSPQLQ DVQTLRENIG KTKQHLDIMV WCIRHGFLDD VRSRYSNFTS WNALVGERKS 301: NAVKRAWPDA VDQSSDCSVQ SASLFIEDAL ENLEREPEYS QEIGADLEVG RLQKDKRSFL RSKIEGTSGS YPFENLRTAA DMLFLHGGSD LVVAKQAIFL 401: YYLFDRHWTT PEKYWKHTID DFAATFGITR HSLLESFVFY LLDDHSEEAL QEACRILPEI CGPETYPKVA QVLLERDNPE TALMVLRWSG RDGVSELVSI 501: GEAVTALRVR VECGLLSEAF TYQRTLCLKV KENNLKNGAV KHASDDLDIW SWTEWMEILV NEFCCLSIRR NLVDRIIELP WNPDEEKYLH RCLLDSATDD 601: PSSAVGSLLV VFYLQRYRYI QAYQVDLRLQ KIEEAFVSDN QIGEEVMFRM RSQSHWRKEL VDRAIDILPV IQQQQVRSGQ FSEMEDASEG AKKSDLPDAP 701: DMITSSVPFA TTNSVFLQSA NNARAREPVA NNGSPFQPGH MIGNASHDLS HGRLFTNANR GQKSEVRSVT KNLKFGEMST PFKDLNRARG NSQLQGKRTE 801: ESSPEVNVDR YIENNMSSPY LRRITANNPV TVKSSSNHLN GSSQKPESTF FGTRMQPDKD NFVDLDDPMD MSSSLKDNNN NVLATESRNN SGGLRWRSDE 901: TSDDEDELTS FGSMPVKGRR RRRFAAR |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)