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AT5G23080.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:30961429 (2019): nucleus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27177187 (2016): nucleus
  • PMID:24134884 (2013): cytoskeleton microtubules
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : SWAP (Suppressor-of-White-APricot)/surp domain-containing protein
Curator
Summary (TAIR10)
Interacts with TATA-box binding protein 2. Contains domains with strong similarity to G-patch and SWAP domains, characteristic of RNA binding and processing proteins. Colocalizes with the splicing regulator SRp34 to subnuclear particles. Role in RNA binding or processing. Mutants display developmental defects, including reduced plant height, polycotyly, and reduced vascularization. Strong genetic interaction between TGH and AMP1.
Computational
Description (TAIR10)
TOUGH (TGH); FUNCTIONS IN: protein binding, RNA binding; INVOLVED IN: multicellular organismal development, phloem or xylem histogenesis, RNA processing; LOCATED IN: nucleus; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1604 (InterPro:IPR011666), SWAP/Surp (InterPro:IPR000061); Has 34939 Blast hits to 19000 proteins in 961 species: Archae - 12; Bacteria - 1387; Metazoa - 18982; Fungi - 3122; Plants - 2233; Viruses - 162; Other Eukaryotes - 9041 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410Y3I1eggNOG:KOG2138EMBL:AB006708EMBL:AK118129
EMBL:AY518689EMBL:BT008588EMBL:CP002688EnsemblPlants:AT5G23080
EnsemblPlants:AT5G23080.1EnsemblPlants:AT5G23080.2entrez:832372ExpressionAtlas:Q8GXN9
GeneID:832372Genevisible:Q8GXN9GO:GO:0003723GO:GO:0005634
GO:GO:0006396GO:GO:0006397GO:GO:0010087GO:GO:0016607
GO:GO:0030422GO:GO:0035196GO:GO:0040008GO:GO:0070878
GO:GO:0070883hmmpanther:PTHR13384hmmpanther:PTHR13384:SF19HOGENOM:HOG000030798
InParanoid:Q8GXN9IntAct:Q8GXN9InterPro:IPR000061InterPro:IPR011666
iPTMnet:Q8GXN9KEGG:ath:AT5G23080KO:K13123OMA:QRPVDLY
PaxDb:Q8GXN9Pfam:PF01805Pfam:PF07713Pfam:Q8GXN9
Pfscan:PS50128PhylomeDB:Q8GXN9PRIDE:Q8GXN9PRO:PR:Q8GXN9
PROSITE:PS50128ProteinModelPortal:Q8GXN9Proteomes:UP000006548RefSeq:NP_001031926.1
RefSeq:NP_197699.2SMART:SM00648SMR:Q8GXN9STRING:3702.AT5G23080.1
SUPFAM:SSF109905TAIR:AT5G23080tair10-symbols:TGHUniGene:At.49050
UniGene:At.71128UniProt:Q8GXN9
Coordinates (TAIR10) chr5:-:7743226..7748889
Molecular Weight (calculated) 104940.00 Da
IEP (calculated) 7.54
GRAVY (calculated) -1.11
Length 930 amino acids
Sequence (TAIR10)
(BLAST)
001: MGSDEEDFVF HGTPIEREEE IASRKKKAVA GASGNLRTLP AWKQEVTDEE GRRRFHGAFT GGYSAGYYNT VGSKEGWAPQ SFTSSRQNRA GARKQSISDF
101: LDEDEKADME GKSLSASSQF DTFGFTAAEH SRKHAEKEQH ERPSAIPGPV PDELVAPVSE SIGVKLLLKM GWRRGHSIKE VRASSDARRE ARKAFLAFYT
201: DENTKETPDS LVSETEVETS LGEDIKISES TPVYVLNPKQ DLHGLGYDPF KHAPEFREKK RSRMSANKEV GFRKPLSMKE SLFGPKSGKI APGFGIGALE
301: ELDVEDEDVY AGYDFDQTYV IEDEQPARQS NDNRLRLTSK EHDVLPGFGA AKNSDYSMER FNPPIIPKDF VARHKFSGPL EAETKPTVSA PPEVPPPADN
401: NLKLLIEGFA TFVSRCGKLY EDLSREKNQS NQLFDFLREG NGHDYYARRL WEEQQKRKDQ SKLTLDVKVS PTVQKMTAET RGSLLGEKPL QRSLKETDTS
501: ASSGGSFQFP TNLSDTFTKS ASSQEAADAV KPFKDDPAKQ ERFEQFLKEK YKGGLRTTDS NRVNSMSESA RAQERLDFEA AAEAIEKGKA YKEVRRATEQ
601: PLDFLAGGLQ FTSGGTEQIK DTGVVDMKSS KTYPKREEFQ WRPSPLLCKR FDLPDPFMGK LPPAPRARNK MDSLVFLPDT VKAASARQVS ESQVPKKETS
701: IEEPEVEVEV ENVERPVDLY KAIFSDDSED DEDQPMNGKI QEGQEKKNEA AATTLNRLIA GDFLESLGKE LGFEVPMEEE IKSRSKPEDS SDKRLDRPGL
801: KEKVEEKTSS LTLGSEEEKS RKKREKSPGK RSGGNDLSSS ESSGDERRRK RYNKKDRHRN DSESDSSSDY HSRDKQGSRS RSKRRESSRE KRSSHKKHSK
901: HRRTKKSSSS RYSSDEEQKE SRREKKRRRD
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)