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AT4G21100.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 0.974
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:28155257 (2017): extracellular region plant-type cell wall
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:16356755 (2006): extracellular region
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : damaged DNA binding protein 1B
Curator
Summary (TAIR10)
One of two closely related genes similar to a damaged DNA binding protein originally described in mammals. May form a complex with DET1 to regulate photomorphogenesis. Loss of function mutations are lethal. The DDB1b protein binds with a number of DWD-containing proteins and may form part of a CUL4-based E3 ubiquitin ligase.
Computational
Description (TAIR10)
damaged DNA binding protein 1B (DDB1B); CONTAINS InterPro DOMAIN/s: WD40 repeat-like-containing domain (InterPro:IPR011046), Cleavage/polyadenylation specificity factor, A subunit, C-terminal (InterPro:IPR004871); BEST Arabidopsis thaliana protein match is: damaged DNA binding protein 1A (TAIR:AT4G05420.1); Has 1459 Blast hits to 1199 proteins in 224 species: Archae - 0; Bacteria - 0; Metazoa - 547; Fungi - 391; Plants - 235; Viruses - 0; Other Eukaryotes - 286 (source: NCBI BLink).
Protein Annotations
BioGrid:13148DIP:DIP-46981NeggNOG:ENOG410XPF6eggNOG:KOG1897
EMBL:AK220648EMBL:AK229805EMBL:AL021960EMBL:AL161554
EMBL:CP002687EnsemblPlants:AT4G21100EnsemblPlants:AT4G21100.1entrez:827857
Gene3D:2.130.10.10GeneID:827857Genevisible:O49552GO:GO:0003684
GO:GO:0005634GO:GO:0006289GO:GO:0009585GO:GO:0009793
GO:GO:0016567GO:GO:0031461GO:GO:0043161Gramene:AT4G21100.1
hmmpanther:PTHR10644HOGENOM:HOG000007241InParanoid:O49552IntAct:O49552
InterPro:IPR004871InterPro:IPR015943InterPro:IPR017986KEGG:ath:AT4G21100
KO:K10610ncoils:CoilOMA:IRTIPIGPaxDb:O49552
Pfam:O49552Pfam:PF03178Pfam:PF10433PhylomeDB:O49552
PIR:T04941PRIDE:O49552PRO:PR:O49552ProteinModelPortal:O49552
Proteomes:UP000006548Reactome:R-ATH-110314Reactome:R-ATH-5696394Reactome:R-ATH-5696395
Reactome:R-ATH-5696400Reactome:R-ATH-6781823Reactome:R-ATH-6782135Reactome:R-ATH-6782210
RefSeq:NP_193842.1SMR:O49552STRING:3702.AT4G21100.1SUPFAM:SSF50978
TAIR:AT4G21100tair10-symbols:DDB1BUniGene:At.32663UniPathway:UPA00143
UniProt:O49552
Coordinates (TAIR10) chr4:-:11258916..11265309
Molecular Weight (calculated) 121186.00 Da
IEP (calculated) 4.97
GRAVY (calculated) -0.09
Length 1088 amino acids
Sequence (TAIR10)
(BLAST)
0001: MSVWNYAVTA QKPTCVTHSC VGNFTSPQEL NLIVAKSTRI EIHLLSPQGL QTILDVPLYG RIATMELFRP HGEAQDFLFV ATERYKFCVL QWDYESSELI
0101: TRAMGDVSDR IGRPTDNGQI GIIDPDCRVI GLHLYDGLFK VIPFDNKGQL KEAFNIRLEE LQVLDIKFLY GCTKPTIAVL YQDNKDARHV KTYEVSLKDK
0201: NFVEGPWSQN NLDNGADLLI PVPSPLCGVL IIGEETIVYC SANAFKAIPI RPSITKAYGR VDLDGSRYLL GDHAGLIHLL VITHEKEKVT GLKIELLGET
0301: SIASSISYLD NAVVFVGSSY GDSQLIKLNL QPDAKGSYVE ILEKYVNLGP IVDFCVVDLE RQGQGQVVTC SGAYKDGSLR IVRNGIGINE QASVELQGIK
0401: GMWSLKSSID EAFDTFLVVS FISETRILAM NIEDELEETE IEGFLSEVQT LFCHDAVYNQ LVQVTSNSVR LVSSTTRELR NKWDAPAGFS VNVATANASQ
0501: VLLATGGGHL VYLEIGDGTL TEVKHVLLEY EVSCLDINPI GDNPNYSQLA AVGMWTDISV RIFVLPDLTL ITKEELGGEI IPRSVLLCAF EGISYLLCAL
0601: GDGHLLNFQL DTSCGKLRDR KKVSLGTRPI TLRTFSSKSA THVFAASDRP AVIYSNNKKL LYSNVNLKEV SHMCPFNSAA FPDSLAIARE GELTIGTIDD
0701: IQKLHIRTIP IGEHARRICH QEQTRTFAIS CLRNEPSAEE SESHFVRLLD AQSFEFLSSY PLDAFECGCS ILSCSFTDDK NVYYCVGTAY VLPEENEPTK
0801: GRILVFIVEE GRLQLITEKE TKGAVYSLNA FNGKLLASIN QKIQLYKWML RDDGTRELQS ECGHHGHILA LYVQTRGDFI AVGDLMKSIS LLIYKHEEGA
0901: IEERARDYNA NWMTAVEILN DDIYLGTDNC FNIFTVKKNN EGATDEERAR MEVVGEYHIG EFVNRFRHGS LVMKLPDSDI GQIPTVIFGT VSGMIGVIAS
1001: LPQEQYAFLE KLQTSLRKVI KGVGGLSHEQ WRSFNNEKRT AEAKGYLDGD LIESFLDLSR GKMEEISKGM DVQVEELCKR VEELTRLH
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)