AT2G39200.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 1.000 ASURE: plasma membrane What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Seven transmembrane MLO family protein | ||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO6 belongs to the clade IV, with AtMLO2, AtMLO3 and AtMLO12. The gene is expressed during early seedling growth, in root tips and cotyledon vascular system, in floral organs (anthers and stigma), and in fruit abscission zone, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). | ||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
MILDEW RESISTANCE LOCUS O 12 (MLO12); FUNCTIONS IN: calmodulin binding; INVOLVED IN: defense response to fungus, incompatible interaction, response to cyclopentenone, leaf senescence, cell death, defense response; LOCATED IN: plasma membrane; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT1G11310.1); Has 552 Blast hits to 537 proteins in 59 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 2; Plants - 545; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr2:-:16356255..16359797 | ||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 66551.60 Da | ||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 9.27 | ||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.09 | ||||||||||||||||||||||||||||||||||||||||||||
| Length | 576 amino acids | ||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MAIKERSLEE TPTWAVAVVC FVLLFISIMI EYFLHFIGHW FKKKHKKALS EALEKVKAEL MLLGFISLLL VVLQTPVSEI CIPRNIAATW HPCSNHQEIA 101: KYGKDYIDDG RKILEDFDSN DFYSPRRNLA TKGYDKCAEK GKVALVSAYG IHQLHIFIFV LAVFHVLYCI ITYALGKTKM KKWKSWERET KTIEYQYAND 201: PERFRFARDT SFGRRHLNIW SKSTFTLWIT CFFRQFFGSV TKVDYLTLRH GFIMAHLPAG SAARFDFQKY IERSLEQDFT VVVGISPLIW CIAVLFILTN 301: THGWDSYLWL PFLPLIVILI VGAKLQMIIS KLGLRIQEKG DVVKGAPVVE PGDDLFWFGR PRFILFLIHL VLFTNAFQLA FFVWSTYEFT LKNCFHHKTE 401: DIAIRITMGV LIQVLCSYIT LPLYALVTQM GTSMRPTIFN DRVANALKKW HHTAKKQTKH GHSGSNTPHS SRPTTPTHGM SPVHLLHNYN NRSLDQQTSF 501: TASPSPPRFS DYSGQGHGHQ HFFDPESQNH SYQREITDSE FSNSHHPQVD MASPVREEKE IVEHVKVDLS EFTFKK |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)