AT2G38440.1
|
Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 0.941 What is SUBAcon? |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Experimental Localisations and PPI |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
SUBAcon links
AGI-AGI relationships |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Description (TAIR10) | protein_coding : SCAR homolog 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a subunit of the WAVE complex. The WAVE complex is required for activation of ARP2/3 complex which functions in actin microfilament nucleation and branching. Mutations cause defects in both the actin and microtubule cytoskeletons that result in aberrant epidermal cell expansion. itb1 mutants showed irregularities in trichome branch positioning and expansion. The SHD domain of this protein binds to BRK1 and overexpression of the SHD domain results in a dominant negative phenotype. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
SCAR homolog 2 (SCAR2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: in 6 processes; LOCATED IN: SCAR complex, plasma membrane, cytoplasm; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding WH2 (InterPro:IPR003124); BEST Arabidopsis thaliana protein match is: SCAR family protein 4 (TAIR:AT5G01730.1); Has 5162 Blast hits to 2275 proteins in 363 species: Archae - 24; Bacteria - 2785; Metazoa - 880; Fungi - 591; Plants - 224; Viruses - 0; Other Eukaryotes - 658 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Coordinates (TAIR10) | chr2:+:16095550..16100851 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 151592.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 4.23 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.62 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 1399 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MPLTRYQSRN EYGLADPDLY QAADKDDPEA LLEGVAMAGL VGILRQLGDL AEFAAEMFHD LHEEVMATAS RSHGLMARVQ QLEAEFPSIE KALLCQTDHS 0101: PFFSNKGVEW HPNLQLEQSV VTSGDLPRCV MDSYEECRGP PRLFLLDKFD ISGAGACLKR YTDPSFVRLE TSSYEESWDD IQREKKSQKA KRRASQWRNG 0201: GTPENALSSH AKLHELFLEE HLEAHHSDPA RVVKLKTRKL DGCSLISKSG ESYMEKFVQT RVDSKISYEI ITQNPGLLTW NMDSARDVVT DIPEISMVGA 0301: MDKSHGGSRA EVSFPSEQEN VANVNMNGGF IEKDIETVPE STYNEVRGTT ITQDSQTVLN GKPGFFQQRS YSEDLTSEAD NYVDAPATME SETETDDECR 0401: PKSRSDTLKD GNHHIYSDAV EERMEDPPQF SFSHSNGNTP VSENGRSSFG KKSTSYSYSD TASISIDDQS DGEKLSGCLP STSSFKSELV DSMSHVTPEA 0501: NKVSHDLNVQ ESVSSSNVDG QTSLSSNGTC SSPRPVSQND QSCSLTVQSL ASEVVETSPE LVRLDLMKGG NDGRKVDPFD SSKSCASFDA KNSDLPSETS 0601: SISSTSEGSR CDSTIEKNCM VASNLVNSGT SPQAFVDSQT GKQLPIADTD FETNSIVACS EVLANSGSDP EERDGRCLTG KLVPCSAGVG MEVSPDTPSK 0701: VCGPSSADGI HLKDTLDDET DCVSVTNVVV DVDSKNSVAD VGSQSSVADI DSQSSVAEIS DEHSCAFGNT ADVSVSESHE DTLENGMSVP SDFNSGVEKL 0801: AGDASPTCSK CDDHISHEGF HDLSGLDNAT TDIVPNVELD VSDNDNDTSS GGVNHAVSLS STRGKGSLPW ISTNTYQSSS DAGEIFHDTV VESDGTLLED 0901: NNPESEIKMH KSPLEVSSEG LSTEPDNKDV ESIESTSPKP SLDQRNRDTE TKSPGESILD DNCIDSTQVY NLNLLESEAI DQAVREQTSY ASHEVADEEL 1001: LQSNVFRGLE FEPQSAGLEF APQSAGIELN RPKQELNLDP TFPSFGFIPE TIPPNPEDMP PLPPMQWLIG KVPHSFPTFM GESVETSSSA LSAAPPIGSS 1101: LNVQIGSPPS ELSVSLGSDE SERLPGGFVH NASEKPLQSS IQFPTMSTDL NSQYDSSELP TIPYQECIED FGSEENNLLA DHAAQNHELV YSQASSLQLP 1201: QVKHEDFKDD ADVHESQSSS DDHHCPETKS LTPTQSTKVE DKGHSVPDAS NAETAESSNT SVQKINPVSV GDAMWPVSCF SVAPTLDTYK TEVVPTVRLP 1301: RPRSPLVDAV AAHDRRKMKK VSEMVHPPIK SKQDDKDSLL AQIRNKSVNL KPAVTTRPSI QTGPRTDLRV AAILEKANTI RMAMAGSDED EDSDSWSDS |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| See Also |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)