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AT1G13980.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
golgi 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:23390202 (2013): Golgi trans-Golgi network
  • PMID:12553910 (2003): Golgi trans-Golgi network
  • PMID:12553900 (2003): endoplasmic reticulum
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : sec7 domain-containing protein
Curator
Summary (TAIR10)
Encodes a GDP/GTP exchange factor for small G-proteins of the ADP ribosylation factor (RAF) class, and as regulator of intracellular trafficking. Homologous to Sec7p and YEC2 from yeast. Involved in the specification of apical-basal pattern formation. Essential for cell division, expansion and adhesion. It appears that heteotypic binding between the DCB and C-terminal domains of two GNOM proteins is required for membrane association, however, GNOM appears to exist predominantly as a heterodimer formed through DCB-DCB interactions.
Computational
Description (TAIR10)
GNOM (GN); FUNCTIONS IN: protein homodimerization activity, GTP:GDP antiporter activity; INVOLVED IN: in 13 processes; LOCATED IN: intracellular; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: SEC7-like (InterPro:IPR000904); BEST Arabidopsis thaliana protein match is: GNOM-like 1 (TAIR:AT5G39500.1); Has 2876 Blast hits to 2436 proteins in 245 species: Archae - 0; Bacteria - 32; Metazoa - 1502; Fungi - 690; Plants - 264; Viruses - 0; Other Eukaryotes - 388 (source: NCBI BLink).
Protein Annotations
BioGrid:23198eggNOG:COG5307eggNOG:KOG0928EMBL:AC007576
EMBL:AC068197EMBL:AK220827EMBL:CP002684EMBL:U36432
EMBL:U36433EMBL:U56140EMBL:U56141EnsemblPlants:AT1G13980
EnsemblPlants:AT1G13980.1EnsemblPlants:AT1G13980.2entrez:837958Gene3D:1.10.1000.11
GeneID:837958Genevisible:Q42510GO:GO:0000911GO:GO:0001736
GO:GO:0005086GO:GO:0005768GO:GO:0005802GO:GO:0005829
GO:GO:0005886GO:GO:0006897GO:GO:0007155GO:GO:0009793
GO:GO:0009826GO:GO:0009880GO:GO:0009942GO:GO:0010008
GO:GO:0010087GO:GO:0010274GO:GO:0010311GO:GO:0010540
GO:GO:0015031GO:GO:0016192GO:GO:0032012GO:GO:0032509
GO:GO:0042802GO:GO:0042803GO:GO:0043547GO:GO:0048209
GO:GO:0048765GO:GO:0071555Gramene:AT1G13980.1Gramene:AT1G13980.2
hmmpanther:PTHR10663hmmpanther:PTHR10663:SF155HOGENOM:HOG000239037InParanoid:Q42510
IntAct:Q42510InterPro:IPR000904InterPro:IPR016024InterPro:IPR023394
InterPro:IPR032691KEGG:ath:AT1G13980KO:K18443OMA:AFTERWM
PaxDb:Q42510Pfam:PF01369Pfam:PF12783Pfam:Q42510
Pfscan:PS50190PhylomeDB:Q42510PIR:S65571PRIDE:Q42510
PRO:PR:Q42510PROSITE:PS50190ProteinModelPortal:Q42510Proteomes:UP000006548
Reactome:R-ATH-199997Reactome:R-ATH-421837Reactome:R-ATH-6807878RefSeq:NP_001184991.1
RefSeq:NP_172851.1SMART:SM00222SMR:Q42510STRING:3702.AT1G13980.1
SUPFAM:SSF48371SUPFAM:SSF48425TAIR:AT1G13980tair10-symbols:EMB30
tair10-symbols:GNtair10-symbols:VAN7UniGene:At.9165UniProt:Q42510
Coordinates (TAIR10) chr1:+:4789587..4794397
Molecular Weight (calculated) 162628.00 Da
IEP (calculated) 5.74
GRAVY (calculated) -0.10
Length 1451 amino acids
Sequence (TAIR10)
(BLAST)
0001: MGRLKLHSGI KAIEEEPEDF ECTDSSNTTT LACMIDTEIA AVLAVMRRNV RWGGRYMSGD DQLEHSLIQS LKALRKQVFS WNQPWHTISP MLYLQPFLDV
0101: IRSDETGAPI TSIALSSVYK ILNLNVIDQN TANIEDAMHL VVDSVTSCRF EVTDPASEEV VLMKILQVLL ACMKNKASVM LSNQHVCTVV NTCFRVVHQA
0201: GMKGELLQRV ARHTMHELVR CIFSHLPDVE RTETTLVNRA GSIKQEKAGV DSDYAIVSKP VEDGNANSEY DVENSMATFA TGAQSLMDDG PVGPGSRKPA
0301: SPYDLHIMTE PYGVPSMVEI FHFLCSLLNV VEHVGMGSRS NTIAFDEDVP LFALNLINSA IELGGSSIRH HPRLLSLIQD ELFRNLMQFG LSMSPLILSM
0401: VCSIVLNLYQ HLRTELKLQL EAFFSCVILR LAQGKYGPSY QQQEVAMEAL VNFCRQKSFM VEMYANLDCD ITCSNVFEEL SNLLSKSTFP VNCPLSAMHI
0501: LALDGLIAVI QGMAERISNG LTGLDLGPVH LDEYTPFWMV KCDNYSDPNH WVSFVRRRKY IKRRLMIGAD HFNRDPKKGL EFLQGTHLLP DKLDPQSVAC
0601: FFRYTAGLDK NLVGDFLGNH DEFCVQVLNE FAGTFDFQYM NLDTALRLFL ETFRLPGESQ KIQRVLEAFS ERYYMQSPEI LANKDAALVL SYSIIMLNTD
0701: QHNVQVKKKM TEEDFIRNNR HINGGNDLPR EFLSELFHSI CNNEIRTTPE QGAGFPEMTP SRWIDLMHKS KKTAPYILAD SRAYLDHDMF AIMSGPTIAA
0801: ISVVFDHAEH EDVYQTCIDG FLAIAKISAC HHLEDVLDDL VVSLCKFTTL LNPSSVDEPV LAFGDDAKAR MATITIFTIA NKYGDYIRTG WRNILDCILR
0901: LHKLGLLPAR VASDAADESE HSSEQGQGKP LANSLSSAHL QSMGTPRRSS GLMGRFSQLL SLDTEEPRSQ PTEQQLAAHQ RTLQTIQKCH IDSIFTESKF
1001: LQAESLLQLA RALIWAAGRP QKGTSSPEDE DTAVFCLELL IAITLNNRDR IVLLWQGVYE HIATIAQSTV MPCNLVDKAI FGLLRICQRL LPYKESLADE
1101: LLRSLQLVLK LDARVADAYC EQIAIEVSRL VKANANHIRS QAGWRTITSL LSITARHPEA SESGFDAVSF VMSEGTHLYP ANYVLCVDAA RQFAESRVGQ
1201: SERSIRALDL MGDSLEFLAK WALSAKENMG EEDFGKMSQD IGEMWLRLVQ GLRKVCLDQR EDVRNHALQS LQKCLGGVDG INLAHSMWSQ CFDKVIFTVL
1301: DDLLEIAAGS QKDYRNMEGT LLLAIKLLSK VFLQQLQELS QLSTFCKLWL GVLTRMEKYM KVKVRGKKSD KLQESVPELL KNILLVMKTK GVLLQRSALG
1401: GDSLWELTWL HVNNIAPSMR LELFPDQESS QLGDDETVSN GLSSPENTTG S
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)