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AT1G10930.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : DNA helicase (RECQl4A)
Curator
Summary (TAIR10)
DNA helicase involved in the maintenance of genome stability by modulation of the DNA damage response and suppression of homologous recombination.
Computational
Description (TAIR10)
RECQ4A; FUNCTIONS IN: helicase activity, ATP-dependent 3'-5' DNA helicase activity, ATP-dependent helicase activity, nucleic acid binding, ATP binding; INVOLVED IN: chromosome organization, response to DNA damage stimulus, double-strand break repair via homologous recombination; LOCATED IN: intracellular; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), RQC domain (InterPro:IPR018982), DNA helicase, ATP-dependent, RecQ type (InterPro:IPR004589), DNA helicase, ATP-dependent, RecQ type, N-terminal (InterPro:IPR018329), DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (InterPro:IPR002464), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), Helicase/RNase D C-terminal, HRDC domain (InterPro:IPR002121); BEST Arabidopsis thaliana protein match is: RECQ helicase L4B (TAIR:AT1G60930.1); Has 34923 Blast hits to 34782 proteins in 2821 species: Archae - 633; Bacteria - 21324; Metazoa - 3687; Fungi - 2728; Plants - 1606; Viruses - 18; Other Eukaryotes - 4927 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-1331-MONOMEREC:3.6.4.12eggNOG:COG0514eggNOG:KOG0351
EMBL:AJ404473EMBL:AY120761EMBL:BT010133EMBL:CP002684
EMBL:U95973EnsemblPlants:AT1G10930EnsemblPlants:AT1G10930.1entrez:837636
Gene3D:1.10.10.10Gene3D:1.10.150.80Gene3D:3.40.50.300GeneID:837636
Genevisible:Q8L840GO:GO:0000724GO:GO:0003676GO:GO:0005524
GO:GO:0005634GO:GO:0006260GO:GO:0006281GO:GO:0006310
GO:GO:0006974GO:GO:0009506GO:GO:0032508GO:GO:0043138
GO:GO:0043140GO:GO:0046872GO:GO:0051276GO:GO:0070417
GO:GO:0071215Gramene:AT1G10930.1hmmpanther:PTHR13710hmmpanther:PTHR13710:SF94
HOGENOM:HOG000148634InParanoid:Q8L840InterPro:IPR001650InterPro:IPR002121
InterPro:IPR002464InterPro:IPR004589InterPro:IPR010997InterPro:IPR011545
InterPro:IPR011991InterPro:IPR014001InterPro:IPR018982InterPro:IPR027417
InterPro:IPR032284KEGG:ath:AT1G10930KO:K10901ncoils:Coil
OMA:WSEHAKAPaxDb:Q8L840Pfam:PF00270Pfam:PF00271
Pfam:PF00570Pfam:PF09382Pfam:PF16124Pfam:Q8L840
Pfscan:PS50967Pfscan:PS51192Pfscan:PS51194PhylomeDB:Q8L840
PIR:B86243PRIDE:Q8L840PRO:PR:Q8L840PROSITE:PS00018
PROSITE:PS00690PROSITE:PS50967PROSITE:PS51192PROSITE:PS51194
ProteinModelPortal:Q8L840Proteomes:UP000006548Reactome:R-ATH-3108214RefSeq:NP_172562.2
scanprosite:PS00690SMART:SM00487SMART:SM00490SMART:SM00956
SMR:Q8L840STRING:3702.AT1G10930.1SUPFAM:SSF47819SUPFAM:SSF52540
TAIR:AT1G10930tair10-symbols:ATRECQ4Atair10-symbols:ATSGS1tair10-symbols:RECQ4A
TIGRfam:TIGR00614TIGRFAMs:TIGR00614UniGene:At.10177UniProt:Q8L840
Coordinates (TAIR10) chr1:-:3648032..3654997
Molecular Weight (calculated) 133320.00 Da
IEP (calculated) 7.22
GRAVY (calculated) -0.53
Length 1188 amino acids
Sequence (TAIR10)
(BLAST)
0001: MINSNQMSRS HLPEVQKPRG PQTNWSEHAK ALESSSSVTK FLSSNVLYAL ESQKPRDMAA RSIAFPSVNV HTLAHPQISK AWRALSSLSV NNTYLRPGVT
0101: PPIDVGTNDS YSARERSTAK VISSTGGSVY SSTRPNLSAM NVSGTGRSFH SFPSSVPGDD KIVAEKFPRG NNEIRESEPS CTHLNGVEKS FGNSAFPAEQ
0201: FESRKACLDD MDDDDILENI DVDQIVMEHY HSTSTPQPSV SNFSLRTPPV DRSASRLEEE CNLPPELCSN CSHGIKLGLC PEASTHVEQM KDVLLAISNE
0301: LLDDATDLSP DRVGQLRQER LRLKKQIQQL ENHIRDKESQ KSQFLSSTAT RIFQYETPKS TNYKMDQPQT DFRAHVSDQG RYACDSWNTP RDSSFSVDRY
0401: GLSSAPVERE QYVPKIIDVT YTEGSNDKKW SSREFPWTRK LEVNNKKVFG NHSFRPNQRE IINATMSGSD VFVLMPTGGG KSLTYQLPAL ICGGITLVIS
0501: PLVSLIQDQI MNLLQANIPA ASLSAGMEWA EQLKIFQELN SEHSKYKLLY VTPEKVAKSD SLLRHLENLN SRGLLARFVI DEAHCVSQWG HDFRPDYQSL
0601: GILKQKFPNI PVLALTATAT ASVKEDVVQA LGLVNCVVFR QSFNRPNLWY SVVPKTKKCL EDIDKFIKEN HFDECGIIYC LSRMDCEKVS ERLQEFGHKA
0701: AFYHGSMEPE QRAFIQTQWS KDEINIICAT VAFGMGINKP DVRFVIHHSL PKSIEGYHQE CGRAGRDGQR SSCVLYYGYG DYIRVKHMIS QGGVDQSPMA
0801: TGYNRVASSG RLLETNTENL LRMVRYCENE VECRRFLQLV HLGEKFDSTN CKKTCDNCCS SQSLIDKDVT LITRQLVELV KQTGERFSSA HILEVYRGSL
0901: NQMVKKHRHE TLQFHGAGKH LSKIEVSRIL HYLVTEDILV EDVRKSDMYG SVSSLLQVNN AKATILFSGS QTIVMKFPSS VKVLKPSKQG ATAAKGPLTS
1001: EKQSTLPLTT EDAPPKDVNL SANMYTALRK LRTALVKEAP DGVMAYHIFI NSTLQQISRR IPRTKEELLE INGLGKAKVS KYGDQLLETI ETTVNEYYGT
1101: NKKDSIISND SPDSGKRRRD ENISPNVAED DDFEVSPSQS CKKTVRNKSN EVLHGECIDG DRRGMELDFD FKDEDGSEIR PEGRVLPW
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)