AT3G24495.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : MUTS homolog 7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH7 exhibit moderate affinity for a (T/G) substrate and weak binding of (+T), suggesting MSH2*MSH7 may be specialized for lesions/base mispairs not tested or for (T/G) mispairs in special contexts. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
MUTS homolog 7 (MSH7); FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695); BEST Arabidopsis thaliana protein match is: MUTS homolog 6 (TAIR:AT4G02070.2); Has 17871 Blast hits to 13835 proteins in 2667 species: Archae - 197; Bacteria - 11731; Metazoa - 1028; Fungi - 1274; Plants - 566; Viruses - 3; Other Eukaryotes - 3072 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr3:-:8912418..8918086 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 122276.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 7.11 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.25 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 1109 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MQRQRSILSF FQKPTAATTK GLVSGDAASG GGGSGGPRFN VKEGDAKGDA SVRFAVSKSV DEVRGTDTPP EKVPRRVLPS GFKPAESAGD ASSLFSNIMH 0101: KFVKVDDRDC SGERSREDVV PLNDSSLCMK ANDVIPQFRS NNGKTQERNH AFSFSGRAEL RSVEDIGVDG DVPGPETPGM RPRASRLKRV LEDEMTFKED 0201: KVPVLDSNKR LKMLQDPVCG EKKEVNEGTK FEWLESSRIR DANRRRPDDP LYDRKTLHIP PDVFKKMSAS QKQYWSVKSE YMDIVLFFKV GKFYELYELD 0301: AELGHKELDW KMTMSGVGKC RQVGISESGI DEAVQKLLAR GYKVGRIEQL ETSDQAKARG ANTIIPRKLV QVLTPSTASE GNIGPDAVHL LAIKEIKMEL 0401: QKCSTVYGFA FVDCAALRFW VGSISDDASC AALGALLMQV SPKEVLYDSK GLSREAQKAL RKYTLTGSTA VQLAPVPQVM GDTDAAGVRN IIESNGYFKG 0501: SSESWNCAVD GLNECDVALS ALGELINHLS RLKLEDVLKH GDIFPYQVYR GCLRIDGQTM VNLEIFNNSC DGGPSGTLYK YLDNCVSPTG KRLLRNWICH 0601: PLKDVESINK RLDVVEEFTA NSESMQITGQ YLHKLPDLER LLGRIKSSVR SSASVLPALL GKKVLKQRVK AFGQIVKGFR SGIDLLLALQ KESNMMSLLY 0701: KLCKLPILVG KSGLELFLSQ FEAAIDSDFP NYQNQDVTDE NAETLTILIE LFIERATQWS EVIHTISCLD VLRSFAIAAS LSAGSMARPV IFPESEATDQ 0801: NQKTKGPILK IQGLWHPFAV AADGQLPVPN DILLGEARRS SGSIHPRSLL LTGPNMGGKS TLLRATCLAV IFAQLGCYVP CESCEISLVD TIFTRLGASD 0901: RIMTGESTFL VECTETASVL QNATQDSLVI LDELGRGTST FDGYAIAYSV FRHLVEKVQC RMLFATHYHP LTKEFASHPR VTSKHMACAF KSRSDYQPRG 1001: CDQDLVFLYR LTEGACPESY GLQVALMAGI PNQVVETASG AAQAMKRSIG ENFKSSELRS EFSSLHEDWL KSLVGISRVA HNNAPIGEDD YDTLFCLWHE 1101: IKSSYCVPK |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)