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AT4G39120.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 1.000
ASURE: plastid
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:30135097 (2018): plastid
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:24124904 (2013): plastid
  • PMID:22550958 (2012): plastid
  • PMID:21311031 (2011): mitochondrion
  • PMID:20423899 (2010): plastid
  • PMID:20061580 (2010): plastid plastid stroma
  • PMID:18431481 (2008): plastid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : myo-inositol monophosphatase like 2
Curator
Summary (TAIR10)
Encodes a chloroplast-localized member of the myo-inositol monophosphatase family, IMPL2 (myo-Inositol monophosphatase like 2) that seems to have multiple enzymatic activities. It contributes to histidine biosynthesis based on it histidinol-phosphate phosphatase activity. In addition, the protein can act as an inositol monophosphatase and an L-galactose-1-phosphate phosphatase in vitro.
Computational
Description (TAIR10)
myo-inositol monophosphatase like 2 (IMPL2); FUNCTIONS IN: histidinol-phosphatase activity, 3'(2'),5'-bisphosphate nucleotidase activity, L-galactose-1-phosphate phosphatase activity, inositol or phosphatidylinositol phosphatase activity, inositol-1(or 4)-monophosphatase activity; INVOLVED IN: sulfur metabolic process, histidine biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histidinol-phosphate phosphatase, putative, inositol monophosphatase (InterPro:IPR011809), Inositol monophosphatase (InterPro:IPR000760), Inositol monophosphatase, metal-binding site (InterPro:IPR020583); BEST Arabidopsis thaliana protein match is: Inositol monophosphatase family protein (TAIR:AT3G02870.1); Has 15134 Blast hits to 15130 proteins in 2267 species: Archae - 157; Bacteria - 8374; Metazoa - 557; Fungi - 304; Plants - 238; Viruses - 0; Other Eukaryotes - 5504 (source: NCBI BLink).
Protein Annotations
BioCyc:MetaCyc:AT4G39120-MONOMERBRENDA:3.1.3.15BRENDA:3.1.3.25EC:3.1.3.15
EC:3.1.3.25EC:3.1.3.93eggNOG:COG0483eggNOG:KOG2951
EMBL:AK118971EMBL:AK175533EMBL:AK176630EMBL:AK220687
EMBL:AL050351EMBL:AL161594EMBL:BT010891EMBL:CP002687
EnsemblPlants:AT4G39120EnsemblPlants:AT4G39120.1entrez:830067GeneID:830067
Genevisible:Q6NPM8GO:GO:0000105GO:GO:0004401GO:GO:0006021
GO:GO:0008934GO:GO:0009507GO:GO:0016311GO:GO:0046854
GO:GO:0046872GO:GO:0052832GO:GO:0052833GO:GO:0052834
Gramene:AT4G39120.1gramene_pathway:3.1.3.-gramene_pathway:3.1.3.15gramene_pathway:3.1.3.25
gramene_pathway:HISTSYN-PWYgramene_pathway:PWY-2301gramene_pathway:PWY-4702gramene_pathway:PWY-882
gramene_plant_reactome:1119509gramene_plant_reactome:6874848hmmpanther:PTHR20854hmmpanther:PTHR20854:SF38
HOGENOM:HOG000282239InParanoid:Q6NPM8InterPro:IPR000760InterPro:IPR011809
InterPro:IPR020583KEGG:00340+3.1.3.15KEGG:ath:AT4G39120KO:K18649
PANTHER:PTHR20854PaxDb:Q6NPM8Pfam:PF00459Pfam:Q6NPM8
PhylomeDB:Q6NPM8PIR:T08560PRIDE:Q6NPM8PRINTS:PR00377
PRO:PR:Q6NPM8PROSITE:PS00629ProteinModelPortal:Q6NPM8Proteomes:UP000006548
RefSeq:NP_195623.3scanprosite:PS00629SMR:Q6NPM8STRING:3702.AT4G39120.1
SUPFAM:SSF56655TAIR:AT4G39120tair10-symbols:HISN7tair10-symbols:IMPL2
TIGRfam:TIGR02067TIGRFAMs:TIGR02067UniGene:At.31118UniPathway:UPA00031
UniPathway:UPA00823UniProt:Q6NPM8
Coordinates (TAIR10) chr4:-:18225578..18227988
Molecular Weight (calculated) 41761.70 Da
IEP (calculated) 6.63
GRAVY (calculated) -0.18
Length 375 amino acids
Sequence (TAIR10)
(BLAST)
001: MRLHNRDLSI QTFSVVDDWL FRELPTHSKM LAQSHFFSKS FDLIPPQSPA LRSANPSLRI SSSYSNSRLS FLSSSAIAVP VSRRRFCLTM ASNSKRPNIS
101: NESPSELSDT ELDRFAAVGN ALADASGEVI RKYFRKKFDI VDKDDMSPVT IADQMAEEAM VSIIFQNLPS HAIYGEEKGW RCKEESADYV WVLDPIDGTK
201: SFITGKPVFG TLIALLYKGK PILGLIDQPI LKERWIGMNG RRTKLNGEDI STRSCPKLSQ AYLYTTSPHL FSEEAEKAYS RVRDKVKVPL YGCDCYAYAL
301: LASGFVDLVI ESGLKPYDFL ALVPVIEGAG GTITDWTGKR FLWEASSSAV ATSFNVVAAG DSDIHQQALE SLEWH
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)