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AT4G29810.2
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
mitochondrion 0.606
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : MAP kinase kinase 2
Curator
Summary (TAIR10)
encodes a MAP kinase kinase 2 that regulates MPK6 and MPK4 in response to cold and salt stresses. Co-expression with MEKK1 in protoplasts activated MKK2 activity, suggesting that MEKK1 may be a regulator of MKK2.
Computational
Description (TAIR10)
MAP kinase kinase 2 (MKK2); FUNCTIONS IN: MAP kinase kinase activity, kinase activity; INVOLVED IN: cold acclimation, MAPKKK cascade, response to salt stress, response to cold, defense response, incompatible interaction; LOCATED IN: plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: MAP kinase/ ERK kinase 1 (TAIR:AT4G26070.3); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410XQ5AeggNOG:KOG0581EMBL:AK317196EnsemblPlants:AT4G29810
EnsemblPlants:AT4G29810.2entrez:829103ExpressionAtlas:B9DGL3GO:GO:0004672
GO:GO:0005524hmmpanther:PTHR24361hmmpanther:PTHR24361:SF385HOGENOM:HOG000234206
InterPro:IPR000719InterPro:IPR008271InterPro:IPR011009InterPro:IPR017441
iPTMnet:B9DGL3PaxDb:B9DGL3Pfam:PF00069Pfscan:PS50011
PRIDE:B9DGL3PROSITE:PS00107PROSITE:PS00108PROSITE:PS50011
ProteinModelPortal:B9DGL3scanprosite:PS00107scanprosite:PS00108SMART:SM00220
STRING:3702.AT4G29810.2SUPFAM:SSF56112tair10-symbols:ATMKK2tair10-symbols:MK1
tair10-symbols:MKK2UniProt:B9DGL3
Coordinates (TAIR10) chr4:-:14593299..14595241
Molecular Weight (calculated) 40855.90 Da
IEP (calculated) 7.18
GRAVY (calculated) -0.14
Length 372 amino acids
Sequence (TAIR10)
(BLAST)
001: MKKGGFSNNL KLAIPVAGEQ SITKFLRKGF GSLCRTQSGT FKDGDLRVNK DGVRIISQLE PEVLSPIKPA DDQLSLSDLD MVKVIGKGSS GVVQLVQHKW
101: TGQFFALKVI QLNIDEAIRK AIAQELKINQ SSQCPNLVTS YQSFYDNGAI SLILEYMDGG SLADFLKSVK AIPDSYLSAI FRQVLQGLIY LHHDRHIIHR
201: DLKPSNLLIN HRGEVKITDF GVSTVMTNTA GLANTFVGTY NYMSPERIVG NKYGNKSDIW SLGLVVLECA TGKFPYAPPN QEETWTSVFE LMEAIVDQPP
301: PALPSGNFSP ELSSFISTCL QKDPNSRSSA KELMEHPFLN KYDYSGINLA SYFTDAGSPL ATLGNLSGTF SV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)