AT5G57090.1
|
Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 1.000 ASURE: plasma membrane What is SUBAcon? |
|
||||||||||||||||||||||||||||||||||||||||||||
| Experimental Localisations and PPI |
|
||||||||||||||||||||||||||||||||||||||||||||
|
SUBAcon links
AGI-AGI relationships |
|
||||||||||||||||||||||||||||||||||||||||||||
| Description (TAIR10) | protein_coding : Auxin efflux carrier family protein | ||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes an auxin efflux carrier that is similar to bacterial membrane transporters. Root-specific role in the transport of auxin. Acts downstream of CTR1 and ethylene biosynthesis, in the same pathway as EIN2 and AUX1, and independent from EIN3 and EIN5/AIN1 pathway. In the root, the protein localizes apically in epidermal and lateral root cap cells and predominantly basally in cortical cells. Functions may be regulated by phosphorylation status. EIR1 expression is induced by brassinolide treatment in the brassinosteroid-insensitive br1 mutant. Gravistimulation resulted in asymmetric PIN2 distribution, with more protein degraded at the upper side of the gravistimulated root. Protein turnover is affected by the proteasome and by endosomal cycling. Plasma membrane-localized PIN proteins mediate a saturable efflux of auxin. PINs mediate auxin efflux from mammalian and yeast cells without needing additional plant-specific factors. The action of PINs in auxin efflux is distinct from PGPs, rate-limiting, specific to auxins and sensitive to auxin transport inhibitors. Membrane sterol composition is essential for the acquisition of PIN2 polarity. | ||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
ETHYLENE INSENSITIVE ROOT 1 (EIR1); CONTAINS InterPro DOMAIN/s: Auxin efflux carrier, subgroup (InterPro:IPR014024), Auxin efflux carrier (InterPro:IPR004776); BEST Arabidopsis thaliana protein match is: Auxin efflux carrier family protein (TAIR:AT2G01420.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
|
||||||||||||||||||||||||||||||||||||||||||||
| Coordinates (TAIR10) | chr5:+:23100765..23104456 | ||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 69335.10 Da | ||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 9.75 | ||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | 0.10 | ||||||||||||||||||||||||||||||||||||||||||||
| Length | 647 amino acids | ||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MITGKDMYDV LAAMVPLYVA MILAYGSVRW WGIFTPDQCS GINRFVAVFA VPLLSFHFIS SNDPYAMNYH FLAADSLQKV VILAALFLWQ AFSRRGSLEW 101: MITLFSLSTL PNTLVMGIPL LRAMYGDFSG NLMVQIVVLQ SIIWYTLMLF LFEFRGAKLL ISEQFPETAG SITSFRVDSD VISLNGREPL QTDAEIGDDG 201: KLHVVVRRSS AASSMISSFN KSHGGGLNSS MITPRASNLT GVEIYSVQSS REPTPRASSF NQTDFYAMFN ASKAPSPRHG YTNSYGGAGA GPGGDVYSLQ 301: SSKGVTPRTS NFDEEVMKTA KKAGRGGRSM SGELYNNNSV PSYPPPNPMF TGSTSGASGV KKKESGGGGS GGGVGVGGQN KEMNMFVWSS SASPVSEANA 401: KNAMTRGSST DVSTDPKVSI PPHDNLATKA MQNLIENMSP GRKGHVEMDQ DGNNGGKSPY MGKKGSDVED GGPGPRKQQM PPASVMTRLI LIMVWRKLIR 501: NPNTYSSLFG LAWSLVSFKW NIKMPTIMSG SISILSDAGL GMAMFSLGLF MALQPKIIAC GKSVAGFAMA VRFLTGPAVI AATSIAIGIR GDLLHIAIVQ 601: AALPQGIVPF VFAKEYNVHP DILSTAVIFG MLVALPVTVL YYVLLGL |
||||||||||||||||||||||||||||||||||||||||||||
| See Also |
|
||||||||||||||||||||||||||||||||||||||||||||
Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)