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AT5G24630.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : double-stranded DNA binding
Curator
Summary (TAIR10)
This gene is predicted to encode a protein that forms part of the topoisomerase VI complex. BIN4 is a nuclear-localized protein that can bind DNA. bin4 mutants are brassinolide-insensitive dwarves with severely reduced cell size in leaves, roots, and hypocotyls. Proper development of root hairs and trichomes is also disrupted in bin4 mutants and they have elevated levels of double strand breaks in their cotyledon cells.
Computational
Description (TAIR10)
brassinosteroid-insensitive4 (BIN4); FUNCTIONS IN: double-stranded DNA binding; INVOLVED IN: in 7 processes; LOCATED IN: DNA topoisomerase complex (ATP-hydrolyzing), nucleus; EXPRESSED IN: 6 plant structures; Has 2751 Blast hits to 2146 proteins in 312 species: Archae - 6; Bacteria - 241; Metazoa - 1096; Fungi - 396; Plants - 170; Viruses - 20; Other Eukaryotes - 822 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410IWS0eggNOG:ENOG410Y5VTEMBL:CP002688EnsemblPlants:AT5G24630
EnsemblPlants:AT5G24630.1entrez:832534ExpressionAtlas:F4KH79GeneID:832534
GO:GO:0003677Gramene:AT5G24630.1hmmpanther:PTHR34810hmmpanther:PTHR34810:SF1
InterPro:IPR033246iPTMnet:F4KH79PANTHER:PTHR34810:SF1PaxDb:F4KH79
PRIDE:F4KH79ProteinModelPortal:F4KH79Proteomes:UP000006548RefSeq:NP_197851.5
STRING:3702.AT5G24630.6TAIR:AT5G24630tair10-symbols:BIN4UniGene:At.54981
UniProt:F4KH79
Coordinates (TAIR10) chr5:-:8432523..8435682
Molecular Weight (calculated) 49239.30 Da
IEP (calculated) 4.93
GRAVY (calculated) -0.89
Length 451 amino acids
Sequence (TAIR10)
(BLAST)
001: MSSSSREGSP DWLRSYEAPM TTSLLSLSSS DDDSPYRESE VISSLPLPDD DGDDIVVLET ESVELLTRKN SETKVVTKQV SIEQVFSRKK KADASLNLEG
101: KENGNNVDCE KLSSKHKDAQ QGGADSVWLV SSDSEPSSPI KQEVTVSTEK DADFVLEATE EEPAVKTVRK EKSPKTKSKS SRKTPKEGNS AQEILKTEDK
201: DTDTTIAEQV TPEKSPKTKS KSSRKTPKEE NCAQEILKTE DKDKDTDTDT IIAEEVTTDQ KIKPSSGSSS RLPLVLSEKV NRTKVLVECE GDSIDLSGDM
301: GAVGRVVVSD TTGDMYLDLK GTIYKSTIIP SRTFCVVNVG QTEAKIEAIM NDFIQLIPQS NVYEAETMVE GTLEGFTFES DDESNKNAKT AVKPADQSVG
401: TEEETNTKAK PKAKAKGETV IGKKRGRPSK EKQPPAKKAR NSAPKKPKAK K
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)