AT5G23720.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 0.541 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : dual specificity protein phosphatase family protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a protein tyrosine phosphatase Propyzamide-Hypersensitive 1 (PHS1). One of the mutant alleles, phs1-1, is hypersensitive to the microtubule-destabilizing drug propyzamide, suggesting that PHS1 may be involved in phosphorylation cascades that control the dynamics of cortical microtubules in plant cells. A second allele, phs1-3, is hypersensitive to abscisic acid, indicating a possible involvement of PHS1 in ABA signalling. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
PROPYZAMIDE-HYPERSENSITIVE 1 (PHS1); FUNCTIONS IN: protein tyrosine/serine/threonine phosphatase activity, phosphoprotein phosphatase activity; INVOLVED IN: cortical microtubule organization, regulation of gene expression, response to abscisic acid stimulus, regulation of stomatal movement; LOCATED IN: cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), Dual-specific/protein-tyrosine phosphatase, conserved region (InterPro:IPR000387), Dual specificity phosphatase, subgroup, catalytic domain (InterPro:IPR020422), Protein kinase-like domain (InterPro:IPR011009), Protein-tyrosine phosphatase, active site (InterPro:IPR016130), Actin-fragmin kinase, catalytic (InterPro:IPR015275), Dual specificity phosphatase, catalytic domain (InterPro:IPR000340); BEST Arabidopsis thaliana protein match is: dual specificity protein phosphatase 1 (TAIR:AT3G23610.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:+:7998309..8002594 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 104240.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.37 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.59 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 929 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MAEPEKKRDQ PFSQEKDEEK DLYLVHDEHE SPLPLTVTSR VLYMLGDIAS GPAYRFTQWL DLVRKRSATY GSSGFPHRLH RIDDMVTSAG ERNTDPKSPP 101: SRQSSEISLW ERLGKASTVD IDSSCFSWNM LSSLHHTEHS SSTDHSEEDQ SKPLEVTVNS GGVVFFALFN SSSSEDASRK EEAAVIKFAS SRMATQSERL 201: GYEFSKWLGV QIPQARVIHS CNPEWTLIKE ATEKAQAKAT SEGDEVGEMT CSELLEALEL SRCLLLMSYV HGCPMLESMS SFETEEKAER AAAALGRILV 301: LDLVIRNEDR LPCRQLRWRG NPANLLLTDR IVSSAKHHEC SFDEAFDSAI KRYHPKDYRS IQRERRASSV DSRSRLSISD QMLVSQASDF SDITESPRSY 401: DTGLMSPMSD RSVAADFHLV AIDSGVPRRP PAGKRASDQE IYPRLVELLL NSSQYSSNLL HEITEGSLGY PQAEDGEETS NVRSVVTPVV REFRNGFRAG 501: LRDLQEFHIF LVTLHQKLDV LLRAFFSMMD KTMCADFDRE DFAVPESPSH THGHEVNHYP SPSKDRVPSD NSSDHSESDM QKSVPRTPNS ENKEDGSSPK 601: SRESWHGRSG KGGESLSSQR LAAKLRDFHK FAKVDAESNK ELDQWNETLR NEVMKLCQEN GFNTGFFEGS DNNSCTDAYE LKVRLEHILE RISLISKAAN 701: TEKPSMIQEN LFIGGGLAAR SIYTLQHLGI THVLCLCANE IGQSDTQYPD LFEYQNFSIT DDEDSNIESI FQEALDFIKH GEETGGKILV HCFEGRSRSA 801: TVVLAYLMLQ KKLTLLEAWS KLRKVHRRAQ PNDGFARILI NLDKKCHGKV SMEWRQRKPT MKVCPVCGKN AGLSSSSLKL HLQKSHRKLS SGSVDSAMNM 901: EIQKALEALK LSTGRGSSAS SNSFQSHPG |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)