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AT5G20320.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : dicer-like 4
Curator
Summary (TAIR10)
Encodes an RNase III-like enzyme that catalyzes processing of trans-acting small interfering RNA precursors in a distinct small RNA biogenesis pathway. The protein is also involved in the production of 21-nt primary siRNAs from both inverted-repeat constructs and endogenous sequences, as well as the RDR6-dependent 21-nt secondary siRNAs involved in long-range cell-to-cell signaling. It binds DRB4, a ds-RNA binding protein.
Computational
Description (TAIR10)
dicer-like 4 (DCL4); CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), Double-stranded RNA-binding (InterPro:IPR001159), Argonaute/Dicer protein, PAZ (InterPro:IPR003100), Ribonuclease III (InterPro:IPR000999), Double-stranded RNA-binding-like (InterPro:IPR014720), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Dicer double-stranded RNA-binding fold (InterPro:IPR005034), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: dicer-like 2 (TAIR:AT3G03300.3); Has 20138 Blast hits to 15531 proteins in 2958 species: Archae - 325; Bacteria - 10957; Metazoa - 2671; Fungi - 1592; Plants - 1161; Viruses - 33; Other Eukaryotes - 3399 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G20320-MONOMERBioCyc:ARA:GQT-2073-MONOMERBioGrid:17430EC:3.1.26.-
eggNOG:COG0571eggNOG:COG1111eggNOG:KOG0701EMBL:AF296825
EMBL:CP002688EMBL:DQ118423EnsemblPlants:AT5G20320EnsemblPlants:AT5G20320.1
entrez:832154EvolutionaryTrace:P84634ExpressionAtlas:P84634Gene3D:1.10.1520.10
Gene3D:3.30.160.20Gene3D:3.40.50.300GeneID:832154Genevisible:P84634
GO:GO:0003723GO:GO:0004386GO:GO:0004525GO:GO:0005524
GO:GO:0005634GO:GO:0005737GO:GO:0006353GO:GO:0009616
GO:GO:0010050GO:GO:0010216GO:GO:0010267GO:GO:0010599
GO:GO:0016442GO:GO:0030422GO:GO:0046872GO:GO:0051607
GO:GO:0090501GO:GO:0090502hmmpanther:PTHR14950hmmpanther:PTHR14950:SF15
HOGENOM:HOG000083706InParanoid:P84634IntAct:P84634InterPro:IPR000999
InterPro:IPR001650InterPro:IPR003100InterPro:IPR005034InterPro:IPR011545
InterPro:IPR014001InterPro:IPR014720InterPro:IPR027417iPTMnet:P84634
MINT:MINT-6948367ncoils:CoilOMA:LDFWKCEPaxDb:P84634
PDB:2KOUPDBsum:2KOUPfam:P84634Pfam:PF00270
Pfam:PF00271Pfam:PF00636Pfam:PF02170Pfam:PF03368
Pfam:PF14709Pfscan:PS50137Pfscan:PS50142Pfscan:PS50821
Pfscan:PS51192Pfscan:PS51194Pfscan:PS51327PhylomeDB:P84634
PRIDE:P84634PRO:PR:P84634PROSITE:PS00517PROSITE:PS50137
PROSITE:PS50142PROSITE:PS50821PROSITE:PS51192PROSITE:PS51194
PROSITE:PS51327ProteinModelPortal:P84634Proteomes:UP000006548RefSeq:NP_197532.3
scanprosite:PS00517SMART:SM00358SMART:SM00487SMART:SM00490
SMART:SM00535SMART:SM00949SMR:P84634STRING:3702.AT5G20320.1
SUPFAM:SSF52540SUPFAM:SSF54768SUPFAM:SSF69065TAIR:AT5G20320
tair10-symbols:ATDCL4tair10-symbols:DCL4UniGene:At.31201UniProt:P84634
Coordinates (TAIR10) chr5:-:6859571..6869068
Molecular Weight (calculated) 191289.00 Da
IEP (calculated) 6.74
GRAVY (calculated) -0.20
Length 1702 amino acids
Sequence (TAIR10)
(BLAST)
0001: MRDEVDLSLT IPSKLLGKRD REQKNCEEEK NKNKKAKKQQ KDPILLHTSA ATHKFLPPPL TMPYSEIGDD LRSLDFDHAD VSSDLHLTSS SSVSSFSSSS
0101: SSLFSAAGTD DPSPKMEKDP RKIARRYQVE LCKKATEENV IVYLGTGCGK THIAVMLIYE LGHLVLSPKK SVCIFLAPTV ALVEQQAKVI ADSVNFKVAI
0201: HCGGKRIVKS HSEWEREIAA NEVLVMTPQI LLHNLQHCFI KMECISLLIF DECHHAQQQS NHPYAEIMKV FYKSESLQRP RIFGMTASPV VGKGSFQSEN
0301: LSKSINSLEN LLNAKVYSVE SNVQLDGFVS SPLVKVYYYR SALSDASQST IRYENMLEDI KQRCLASLKL LIDTHQTQTL LSMKRLLKRS HDNLIYTLLN
0401: LGLWGAIQAA KIQLNSDHNV QDEPVGKNPK SKICDTYLSM AAEALSSGVA KDENASDLLS LAALKEPLFS RKLVQLIKIL SVFRLEPHMK CIIFVNRIVT
0501: ARTLSCILNN LELLRSWKSD FLVGLSSGLK SMSRRSMETI LKRFQSKELN LLVATKVGEE GLDIQTCCLV IRYDLPETVT SFIQSRGRAR MPQSEYAFLV
0601: DSGNEKEMDL IENFKVNEDR MNLEITYRSS EETCPRLDEE LYKVHETGAC ISGGSSISLL YKYCSRLPHD EFFQPKPEFQ FKPVDEFGGT ICRITLPANA
0701: PISEIESSLL PSTEAAKKDA CLKAVHELHN LGVLNDFLLP DSKDEIEDEL SDDEFDFDNI KGEGCSRGDL YEMRVPVLFK QKWDPSTSCV NLHSYYIMFV
0801: PHPADRIYKK FGFFMKSPLP VEAETMDIDL HLAHQRSVSV KIFPSGVTEF DNDEIRLAEL FQEIALKVLF ERGELIPDFV PLELQDSSRT SKSTFYLLLP
0901: LCLHDGESVI SVDWVTIRNC LSSPIFKTPS VLVEDIFPPS GSHLKLANGC WNIDDVKNSL VFTTYSKQFY FVADICHGRN GFSPVKESST KSHVESIYKL
1001: YGVELKHPAQ PLLRVKPLCH VRNLLHNRMQ TNLEPQELDE YFIEIPPELS HLKIKGLSKD IGSSLSLLPS IMHRMENLLV AIELKHVLSA SIPEIAEVSG
1101: HRVLEALTTE KCHERLSLER LEVLGDAFLK FAVSRHLFLH HDSLDEGELT RRRSNVVNNS NLCRLAIKKN LQVYIRDQAL DPTQFFAFGH PCRVTCDEVA
1201: SKEVHSLNRD LGILESNTGE IRCSKGHHWL YKKTIADVVE ALVGAFLVDS GFKGAVKFLK WIGVNVDFES LQVQDACIAS RRYLPLTTRN NLETLENQLD
1301: YKFLHKGLLV QAFIHPSYNR HGGGCYQRLE FLGDAVLDYL MTSYFFTVFP KLKPGQLTDL RSLSVNNEAL ANVAVSFSLK RFLFCESIYL HEVIEDYTNF
1401: LASSPLASGQ SEGPRCPKVL GDLVESCLGA LFLDCGFNLN HVWTMMLSFL DPVKNLSNLQ ISPIKELIEL CQSYKWDREI SATKKDGAFT VELKVTKNGC
1501: CLTVSATGRN KREGTKKAAQ LMITNLKAHE NITTSHPLED VLKNGIRNEA KLIGYNEDPI DVVDLVGLDV ENLNILETFG GNSERSSSYV IRRGLPQAPS
1601: KTEDRLPQKA IIKAGGPSSK TAKSLLHETC VANCWKPPHF ECCEEEGPGH LKSFVYKVIL EVEDAPNMTL ECYGEARATK KGAAEHAAQA AIWCLKHSGF
1701: LC
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)