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AT5G17400.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
endoplasmic reticulum 1.000
ASURE: endoplasmic reticulum
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : endoplasmic reticulum-adenine nucleotide transporter 1
Curator
Summary (TAIR10)
This gene is predicted to encode an ER-localized adenine nucleotide transporter with six putative transmembrane helices. It appears to act as a ATP:ADP antiporter when expressed in E.coli plasma membranes. Transcript levels for several ER-localized chaperones (e.g. BIP1/2) and other ATP-requiring ER proteins (e.g. CPK2) are reduced in er-ant1 knock-out lines, suggesting a lack of adequate ATP transport into the ER in these mutants. They also have reduced seed oil and seed protein levels.
Computational
Description (TAIR10)
endoplasmic reticulum-adenine nucleotide transporter 1 (ER-ANT1); CONTAINS InterPro DOMAIN/s: Mitochondrial carrier protein (InterPro:IPR002067), Mitochondrial substrate carrier (InterPro:IPR001993), Mitochondrial substrate/solute carrier (InterPro:IPR018108), Adenine nucleotide translocator 1 (InterPro:IPR002113); BEST Arabidopsis thaliana protein match is: ADP/ATP carrier 3 (TAIR:AT4G28390.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410XNW0eggNOG:KOG0749EMBL:AL391142EMBL:AY087494
EMBL:CP002688EnsemblPlants:AT5G17400EnsemblPlants:AT5G17400.1entrez:831606
Gene3D:1.50.40.10GeneID:831606Genevisible:Q8LB08GO:GO:0003735
GO:GO:0005471GO:GO:0005743GO:GO:0005789GO:GO:0006412
GO:GO:0015866GO:GO:0015867GO:GO:0016021GO:GO:0048316
GO:GO:0048364GO:GO:0048367GO:GO:0051503Gramene:AT5G17400.1
hmmpanther:PTHR24089hmmpanther:PTHR24089:SF316HOGENOM:HOG000165727InParanoid:Q8LB08
InterPro:IPR002067InterPro:IPR002113InterPro:IPR018108InterPro:IPR023395
KEGG:ath:AT5G17400KO:K05863OMA:IMGITLYPaxDb:Q8LB08
Pfam:PF00153Pfam:Q8LB08Pfscan:PS50920PIR:T51577
PRIDE:Q8LB08PRINTS:PR00926PRINTS:PR00927PRO:PR:Q8LB08
PROSITE:PS50920ProteinModelPortal:Q8LB08Proteomes:UP000006548Reactome:R-ATH-422356
RefSeq:NP_568345.1SMR:Q8LB08STRING:3702.AT5G17400.1SUPFAM:0048588
SUPFAM:SSF103506TAIR:AT5G17400tair10-symbols:ER-ANT1TCDB:2.A.29.1.6
TMHMM:TMhelixUniGene:At.31555UniProt:Q8LB08
Coordinates (TAIR10) chr5:-:5729015..5730104
Molecular Weight (calculated) 33790.20 Da
IEP (calculated) 10.22
GRAVY (calculated) 0.04
Length 306 amino acids
Sequence (TAIR10)
(BLAST)
001: MALIGKSERF SADFVMGGAA AIVAKSAAAP IERVKLLLQN QGEMIKTGHL IRPYTGLGNC FTRIYREEGV LSFWRGNQAN VIRYFPTQAS NFAFKGYFKN
101: LLGCSKEKDG YLKWFAGNVA SGSAAGATTS LFLYHLDYAR TRLGTDAKEC SVNGKRQFKG MIDVYRKTLS SDGIKGLYRG FGVSIVGITL YRGMYFGMYD
201: TIKPIVLVGS LEGNFLASFL LGWSITTSAG VIAYPFDTLR RRMMLTSGQP VKYRNTIHAL REILKSEGFY ALYRGVTANM LLGVAGAGVL AGYDQLHQIA
301: YKHWVQ
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)