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AT4G34890.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 0.996
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31186290 (2019): cytosol None
  • PMID:23903016 (2013): plant-type vacuole plant-type vacuole membrane
  • PMID:21166475 (2011): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : xanthine dehydrogenase 1
Curator
Summary (TAIR10)
Encodes a xanthine dehydrogenase, involved in purine catabolism. Ubiquitously expressed, but the transcript level is altered during aging, senescence, salt and cold stress, ABA treatment, and dark treatment. RNAi lines that suppress both XDH1 and XDH2 produce small plants with reduced fertility and accelerated leaf senescence. Role in drought tolerance.
Computational
Description (TAIR10)
xanthine dehydrogenase 1 (XDH1); CONTAINS InterPro DOMAIN/s: Aldehyde oxidase/xanthine dehydrogenase (InterPro:IPR016208), Ferredoxin (InterPro:IPR001041), Molybdopterin dehydrogenase, FAD-binding (InterPro:IPR002346), [2Fe-2S]-binding (InterPro:IPR002888), FAD-binding, type 2, subdomain 1 (InterPro:IPR016167), FAD-binding, type 2 (InterPro:IPR016166), CO dehydrogenase flavoprotein, C-terminal (InterPro:IPR005107), 2Fe-2S ferredoxin, iron-sulphur binding site (InterPro:IPR006058), CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 (InterPro:IPR016169), Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead (InterPro:IPR000674), Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding (InterPro:IPR008274); BEST Arabidopsis thaliana protein match is: xanthine dehydrogenase 2 (TAIR:AT4G34900.1); Has 21952 Blast hits to 20911 proteins in 1336 species: Archae - 451; Bacteria - 13165; Metazoa - 1072; Fungi - 101; Plants - 265; Viruses - 0; Other Eukaryotes - 6898 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G34890-MONOMERBioCyc:MetaCyc:AT4G34890-MONOMERBioGrid:14923BRENDA:1.17.1.4
EC:1.17.1.4eggNOG:COG4630eggNOG:COG4631eggNOG:KOG0430
EMBL:AL079347EMBL:AL161586EMBL:AY171562EMBL:CP002687
EnsemblPlants:AT4G34890EnsemblPlants:AT4G34890.1entrez:829641Gene3D:1.10.150.120
Gene3D:3.10.20.30Gene3D:3.30.365.10Gene3D:3.30.43.10Gene3D:3.30.465.10
Gene3D:3.90.1170.50GeneID:829641Genevisible:Q8GUQ8GO:GO:0000302
GO:GO:0004854GO:GO:0005506GO:GO:0005829GO:GO:0006145
GO:GO:0009055GO:GO:0009414GO:GO:0016614GO:GO:0016903
GO:GO:0042554GO:GO:0046110GO:GO:0050660GO:GO:0051537
Gramene:AT4G34890.1gramene_pathway:1.17.1.4gramene_pathway:PWY-5695gramene_pathway:PWY-6596
gramene_pathway:PWY-6606gramene_pathway:PWY-6607hmmpanther:PTHR11908hmmpanther:PTHR11908:SF66
HOGENOM:HOG000191197InParanoid:Q8GUQ8InterPro:IPR000674InterPro:IPR001041
InterPro:IPR002346InterPro:IPR002888InterPro:IPR005107InterPro:IPR006058
InterPro:IPR008274InterPro:IPR012675InterPro:IPR016166InterPro:IPR016167
InterPro:IPR016169InterPro:IPR016208iPTMnet:Q8GUQ8KEGG:ath:AT4G34890
KO:K00106OMA:CRQIMERPaxDb:Q8GUQ8Pfam:PF00111
Pfam:PF00941Pfam:PF01315Pfam:PF01799Pfam:PF02738
Pfam:PF03450Pfam:Q8GUQ8Pfscan:PS51085Pfscan:PS51387
PhylomeDB:Q8GUQ8PIR:T10235PIRSF:PIRSF000127PRIDE:Q8GUQ8
PRO:PR:Q8GUQ8PROSITE:PS00197PROSITE:PS51085PROSITE:PS51387
ProteinModelPortal:Q8GUQ8Proteomes:UP000006548Reactome:R-ATH-74259Reactome:R-ATH-964975
RefSeq:NP_195215.2scanprosite:PS00197SMART:SM01008SMART:SM01092
SMR:Q8GUQ8STRING:3702.AT4G34890.1SUPFAM:SSF47741SUPFAM:SSF54292
SUPFAM:SSF54665SUPFAM:SSF55447SUPFAM:SSF56003SUPFAM:SSF56176
TAIR:AT4G34890tair10-symbols:ATXDH1tair10-symbols:XDH1UniGene:At.27839
UniProt:Q8GUQ8
Coordinates (TAIR10) chr4:-:16618736..16624983
Molecular Weight (calculated) 149204.00 Da
IEP (calculated) 6.64
GRAVY (calculated) -0.10
Length 1361 amino acids
Sequence (TAIR10)
(BLAST)
0001: MGSLKKDGEI GDEFTEALLY VNGVRRVLPD GLAHMTLLEY LRDLGLTGTK LGCGEGGCGA CTVMVSSYDR KSKTSVHYAV NACLAPLYSV EGMHVISIEG
0101: LGHRKLGLHP VQESLASSHG SQCGFCTPGF IMSMYSLLRS SKNSPSEEEI EECLAGNLCR CTGYRPIVDA FRVFAKSDDA LYCGVSSLSL QDGSTICPST
0201: GKPCSCGSKT TNEVASCNED RFQSISYSDI DGAKYTDKEL IFPPELLLRK LTPLKLRGNG GITWYRPVCL QNLLELKANY PDAKLLVGNT EVGIEMRLKR
0301: LQYQVLISVA QVPELNALNV NDNGIEVGSA LRLSELLRLF RKIVKERPAH ETSACKAFIE QLKWFAGTQI RNVACIGGNI CTASPISDLN PLWMASRAEF
0401: RITNCNGDVR SIPAKDFFLG YRKVDMGSNE ILLSVFLPWT RPLEYVKEFK QAHRRDDDIA IVNGGMRVFL EDKGQQLFVS DASIAYGGVA PLSLCARKTE
0501: EFLIGKNWNK DLLQDALKVI QSDVVIKEDA PGGMVEFRKS LTLSFFFKFF LWVSHNVNNA NSAIETFPPS HMSAVQPVPR LSRIGKQDYE TVKQGTSVGS
0601: SEVHLSARMQ VTGEAEYTDD TPVPPNTLHA AFVLSKVPHA RILSIDDSAA KSSSGFVGLF LAKDIPGDNM IGPIVPDEEL FATDVVTCVG QVIGVVVADT
0701: HENAKTAAGK VDVRYEELPA ILSIKEAINA KSFHPNTEKR LRKGDVELCF QSGQCDRVIE GEVQMGGQEH FYLEPNGSLV WTVDGGSEVH MISSTQAPQK
0801: HQKYVSHVLG LPMSKVVCKT KRIGGGFGGK ETRSAFIAAA ASVPSYLLNR PVKLILDRDV DMMITGHRHS FLGKYKVGFT NEGKILALDL EIYNNGGNSL
0901: DLSLSVLERA MFHSDNVYEI PHVRIVGNVC FTNFPSNTAF RGFGGPQGML ITENWIQRIA AELNKSPEEI KEMNFQVEGS VTHYCQTLQH CTLHQLWKEL
1001: KVSCNFLKAR READEFNSHN RWKKRGVAMV PTKFGISFTT KFMNQAGALV HVYTDGTVLV THGGVEMGQG LHTKVAQVAA SAFNIPLSSV FVSETSTDKV
1101: PNASPTAASA SSDMYGAAVL DACEQIIARM EPVASKHNFN TFTELVSACY FQRIDLSAHG FHIVPDLGFD WISGKGNAFR YYTYGAAFAE VEIDTLTGDF
1201: HTRAADIMLD LGYSLNPAID VGQIEGAFVQ GLGWVALEEL KWGDAAHKWI KPGSLLTCGP GNYKIPSIND MPFNLNVSLL KGNPNTKAIH SSKAVGEPPF
1301: FLASSVFFAI KEAIKAARTE VGLTDWFPLE SPATPERIRM ACFDEFSAPF VNSDFYPNLS V
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)