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AT4G08920.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 0.500
nucleus 0.500
ASURE: cytosol,nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : cryptochrome 1
Curator
Summary (TAIR10)
Encodes CRY1, a flavin-type blue-light photoreceptor with ATP binding and autophosphorylation activity. Functions in perception of blue / green ratio of light. The photoreceptor may be involved in electron transport. Mutant phenotype displays a blue light-dependent inhibition of hypocotyl elongation. Photoreceptor activity requires light-induced homodimerisation of the N-terminal CNT1 domains of CRY1. Involved in blue-light induced stomatal opening. The C-terminal domain of the protein undergoes a light dependent conformational change. Also involved in response to circadian rhythm. Mutants exhibit long hypocotyl under blue light and are out of phase in their response to circadian rhythm. CRY1 is present in the nucleus and cytoplasm. Different subcellular pools of CRY1 have different functions during photomorphogenesis of Arabidopsis seedlings.
Computational
Description (TAIR10)
cryptochrome 1 (CRY1); CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Cryptochrome/DNA photolyase, class 1 conserved site, C-terminal (InterPro:IPR018394), DNA photolyase, N-terminal (InterPro:IPR006050), Cryptochrome C-terminal (InterPro:IPR020978), DNA photolyase, FAD-binding/Cryptochrome, C-terminal (InterPro:IPR005101), Cryptochrome, plant (InterPro:IPR014134), Cryptochrome/DNA photolyase, class 1 (InterPro:IPR002081); BEST Arabidopsis thaliana protein match is: cryptochrome 2 (TAIR:AT1G04400.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-2162-MONOMERBioGrid:11769DisProt:DP00474eggNOG:COG0415
eggNOG:KOG0133EMBL:AF128396EMBL:AF361588EMBL:AL161513
EMBL:AY124863EMBL:CP002687EMBL:S66907EMBL:S66909
EnsemblPlants:AT4G08920EnsemblPlants:AT4G08920.1entrez:826470EvolutionaryTrace:Q43125
Gene3D:3.40.50.620GeneID:826470Genevisible:Q43125GO:GO:0004672
GO:GO:0005524GO:GO:0005634GO:GO:0005737GO:GO:0006915
GO:GO:0006952GO:GO:0007623GO:GO:0009414GO:GO:0009416
GO:GO:0009583GO:GO:0009637GO:GO:0009638GO:GO:0009640
GO:GO:0009644GO:GO:0009646GO:GO:0009785GO:GO:0009882
GO:GO:0010075GO:GO:0010114GO:GO:0010117GO:GO:0010118
GO:GO:0010218GO:GO:0010244GO:GO:0010310GO:GO:0010343
GO:GO:0010617GO:GO:0016301GO:GO:0016604GO:GO:0018298
GO:GO:0042752GO:GO:0042802GO:GO:0046283GO:GO:0046777
GO:GO:0046872GO:GO:0051510GO:GO:0055114GO:GO:0060918
GO:GO:0071000GO:GO:0071949GO:GO:0072387GO:GO:0099402
GO:GO:1900426GO:GO:1901332GO:GO:1901371GO:GO:1901529
GO:GO:1901672GO:GO:1902347GO:GO:1902448GO:GO:2000377
Gramene:AT4G08920.1hmmpanther:PTHR11455hmmpanther:PTHR11455:SF24HOGENOM:HOG000245621
InParanoid:Q43125IntAct:Q43125InterPro:IPR002081InterPro:IPR005101
InterPro:IPR006050InterPro:IPR014134InterPro:IPR014729InterPro:IPR018394
InterPro:IPR020978iPTMnet:Q43125KEGG:ath:AT4G08920KO:K12118
MINT:MINT-192438ncoils:CoilOMA:QFPSEENPaxDb:Q43125
PDB:1U3CPDB:1U3DPDBsum:1U3CPDBsum:1U3D
Pfam:PF00875Pfam:PF03441Pfam:PF12546Pfam:Q43125
Pfscan:PS51645PIR:H85089PIR:S39058PRIDE:Q43125
PRINTS:PR00147PRO:PR:Q43125PROSITE:PS00394PROSITE:PS00691
PROSITE:PS51645ProteinModelPortal:Q43125Proteomes:UP000006548RefSeq:NP_567341.1
scanprosite:PS00394scanprosite:PS00691SMR:Q43125STRING:3702.AT4G08920.1
SUPFAM:SSF48173SUPFAM:SSF52425TAIR:AT4G08920tair10-symbols:ATCRY1
tair10-symbols:BLU1tair10-symbols:CRY1tair10-symbols:HY4tair10-symbols:OOP2
TIGRfam:TIGR02766TIGRFAMs:TIGR02766UniGene:At.27730UniProt:Q43125
Coordinates (TAIR10) chr4:+:5724260..5726905
Molecular Weight (calculated) 76698.70 Da
IEP (calculated) 5.03
GRAVY (calculated) -0.47
Length 681 amino acids
Sequence (TAIR10)
(BLAST)
001: MSGSVSGCGS GGCSIVWFRR DLRVEDNPAL AAAVRAGPVI ALFVWAPEEE GHYHPGRVSR WWLKNSLAQL DSSLRSLGTC LITKRSTDSV ASLLDVVKST
101: GASQIFFNHL YDPLSLVRDH RAKDVLTAQG IAVRSFNADL LYEPWEVTDE LGRPFSMFAA FWERCLSMPY DPESPLLPPK KIISGDVSKC VADPLVFEDD
201: SEKGSNALLA RAWSPGWSNG DKALTTFING PLLEYSKNRR KADSATTSFL SPHLHFGEVS VRKVFHLVRI KQVAWANEGN EAGEESVNLF LKSIGLREYS
301: RYISFNHPYS HERPLLGHLK FFPWAVDENY FKAWRQGRTG YPLVDAGMRE LWATGWLHDR IRVVVSSFFV KVLQLPWRWG MKYFWDTLLD ADLESDALGW
401: QYITGTLPDS REFDRIDNPQ FEGYKFDPNG EYVRRWLPEL SRLPTDWIHH PWNAPESVLQ AAGIELGSNY PLPIVGLDEA KARLHEALSQ MWQLEAASRA
501: AIENGSEEGL GDSAEVEEAP IEFPRDITME ETEPTRLNPN RRYEDQMVPS ITSSLIRPEE DEESSLNLRN SVGDSRAEVP RNMVNTNQAQ QRRAEPASNQ
601: VTAMIPEFNI RIVAESTEDS TAESSSSGRR ERSGGIVPEW SPGYSEQFPS EENGIGGGST TSSYLQNHHE ILNWRRLSQT G
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)