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AT3G24320.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
mitochondrion 0.500
plastid 0.500
ASURE: mitochondrion,plastid
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : MUTL protein homolog 1
Curator
Summary (TAIR10)
Promotes re-arrangements of mitochondrial genome. Mutations affects mitochondrial gene expression, and impairs mitochondrial function. Dual targeting of the protein to mitochondria and chloroplasts caused by alternative translation initiation.
Computational
Description (TAIR10)
MUTL protein homolog 1 (MSH1); FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, catalytic activity, ATP binding, nuclease activity; INVOLVED IN: mismatch repair, mitochondrial genome maintenance, mitochondrial DNA metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Serine/cysteine peptidase, trypsin-like (InterPro:IPR009003), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), Excinuclease ABC, C subunit, N-terminal (InterPro:IPR000305), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695); BEST Arabidopsis thaliana protein match is: MUTS homolog 6 (TAIR:AT4G02070.2); Has 14048 Blast hits to 12806 proteins in 2713 species: Archae - 218; Bacteria - 10179; Metazoa - 621; Fungi - 751; Plants - 393; Viruses - 3; Other Eukaryotes - 1883 (source: NCBI BLink).
Protein Annotations
eggNOG:COG0249eggNOG:KOG0217EMBL:AP000382EMBL:AY191303
EMBL:CP002686EnsemblPlants:AT3G24320EnsemblPlants:AT3G24320.1entrez:822021
Gene3D:3.40.1170.10Gene3D:3.40.50.300GeneID:822021Genevisible:Q84LK0
GO:GO:0000002GO:GO:0003684GO:GO:0005524GO:GO:0005739
GO:GO:0006298GO:GO:0009408GO:GO:0009507GO:GO:0030983
GO:GO:0032042Gramene:AT3G24320.1hmmpanther:PTHR11361hmmpanther:PTHR11361:SF82
HOGENOM:HOG000264796InParanoid:Q84LK0InterPro:IPR000305InterPro:IPR000432
InterPro:IPR007695InterPro:IPR016151InterPro:IPR027417KEGG:ath:AT3G24320
OMA:ILVNECSPaxDb:Q84LK0Pfam:PF00488Pfam:PF01541
Pfam:PF01624Pfam:Q84LK0PhylomeDB:Q84LK0PRIDE:Q84LK0
PRO:PR:Q84LK0PROSITE:PS00486ProteinModelPortal:Q84LK0Proteomes:UP000006548
RefSeq:NP_189075.2scanprosite:PS00486SMART:SM00534SMR:Q84LK0
STRING:3702.AT3G24320.1SUPFAM:0040970SUPFAM:SSF52540SUPFAM:SSF55271
SUPFAM:SSF82771TAIR:AT3G24320tair10-symbols:ATMSH1tair10-symbols:CHM
tair10-symbols:CHM1tair10-symbols:MSH1UniGene:At.43463UniProt:Q84LK0
Coordinates (TAIR10) chr3:-:8823229..8829571
Molecular Weight (calculated) 123927.00 Da
IEP (calculated) 7.65
GRAVY (calculated) -0.17
Length 1118 amino acids
Sequence (TAIR10)
(BLAST)
0001: MHWIATRNAV VSFPKWRFFF RSSYRTYSSL KPSSPILLNR RYSEGISCLR DGKSLKRITT ASKKVKTSSD VLTDKDLSHL VWWKERLQTC KKPSTLQLIE
0101: RLMYTNLLGL DPSLRNGSLK DGNLNWEMLQ FKSRFPREVL LCRVGEFYEA IGIDACILVE YAGLNPFGGL RSDSIPKAGC PIMNLRQTLD DLTRNGYSVC
0201: IVEEVQGPTP ARSRKGRFIS GHAHPGSPYV YGLVGVDHDL DFPDPMPVVG ISRSARGYCM ISIFETMKAY SLDDGLTEEA LVTKLRTRRC HHLFLHASLR
0301: HNASGTCRWG EFGEGGLLWG ECSSRNFEWF EGDTLSELLS RVKDVYGLDD EVSFRNVNVP SKNRPRPLHL GTATQIGALP TEGIPCLLKV LLPSTCSGLP
0401: SLYVRDLLLN PPAYDIALKI QETCKLMSTV TCSIPEFTCV SSAKLVKLLE QREANYIEFC RIKNVLDDVL HMHRHAELVE ILKLLMDPTW VATGLKIDFD
0501: TFVNECHWAS DTIGEMISLD ENESHQNVSK CDNVPNEFFY DMESSWRGRV KGIHIEEEIT QVEKSAEALS LAVAEDFHPI ISRIKATTAS LGGPKGEIAY
0601: AREHESVWFK GKRFTPSIWA GTAGEDQIKQ LKPALDSKGK KVGEEWFTTP KVEIALVRYH EASENAKARV LELLRELSVK LQTKINVLVF ASMLLVISKA
0701: LFSHACEGRR RKWVFPTLVG FSLDEGAKPL DGASRMKLTG LSPYWFDVSS GTAVHNTVDM QSLFLLTGPN GGGKSSLLRS ICAAALLGIS GLMVPAESAC
0801: IPHFDSIMLH MKSYDSPVDG KSSFQVEMSE IRSIVSQATS RSLVLIDEIC RGTETAKGTC IAGSVVESLD TSGCLGIVST HLHGIFSLPL TAKNITYKAM
0901: GAENVEGQTK PTWKLTDGVC RESLAFETAK REGVPESVIQ RAEALYLSVY AKDASAEVVK PDQIITSSNN DQQIQKPVSS ERSLEKDLAK AIVKICGKKM
1001: IEPEAIECLS IGARELPPPS TVGSSCVYVM RRPDKRLYIG QTDDLEGRIR AHRAKEGLQG SSFLYLMVQG KSMACQLETL LINQLHEQGY SLANLADGKH
1101: RNFGTSSSLS TSDVVSIL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)