AT2G31660.1
|
Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 0.500 nucleus 0.500 ASURE: cytosol,nucleus What is SUBAcon? |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Experimental Localisations and PPI |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
SUBAcon links
AGI-AGI relationships |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Description (TAIR10) | protein_coding : ARM repeat superfamily protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
SAD2 (super sensitive to ABA and drought 2) encodes an importin beta-domain family protein likely to be involved in nuclear transport in ABA signaling. Subcellular localization of GFP-tagged SAD2 showed a predominantly nuclear localization, consistent with a role for SAD2 in nuclear transport. Mutation of SAD2 in Arabidopsis alters abscisic acid sensitivity. SAD2 was ubiquitously expressed at low levels in all tissues except flowers. SAD2 expression was not induced by ABA or stress. Loss of function mutations in SAD2 exhibit increased tolerance for UV stress, increased production of UV protective secondary metabolites and suppression of nuclear localization of MYB4 (a repressor of UV stress response genes). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
SUPER SENSITIVE TO ABA AND DROUGHT2 (SAD2); FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: protein import into nucleus, docking, protein import into nucleus; LOCATED IN: nucleus, nuclear pore, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Importin-beta, N-terminal (InterPro:IPR001494), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024), Exportin/Importin, Cse1-like (InterPro:IPR013713); BEST Arabidopsis thaliana protein match is: ARM repeat superfamily protein (TAIR:AT3G59020.1); Has 3689 Blast hits to 2792 proteins in 293 species: Archae - 3; Bacteria - 183; Metazoa - 1271; Fungi - 834; Plants - 368; Viruses - 60; Other Eukaryotes - 970 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Coordinates (TAIR10) | chr2:+:13464519..13471353 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 119254.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 4.51 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.22 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 1040 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MDLHSLALIL RTAALSPIPD ERKVSEQQLN QLEHTPQHLV RLLQIAVDGN CDMAVRQIAS IQFKNLIAKN WSPEDCGPAV RQQQIFESDK ELVRDNILVY 0101: VTQVPTLLRS QLGESLKTII YADYPEQWPR LLDWVKYNLQ NQQIYGALFV LRILSRKYEF KSDEERTPVS RIVEETFPQL LTIFNGLIQI PNPSLEIAEL 0201: MKLICKIFWS SIYLELPRQL FDLNVFNAWM VLFLSVSERP VPVEGQPMDP ELRKSWGWWK VKKWTVHILN RLYSRFGDPK LQSPENKPFA QMFQKNYAGR 0301: ILEGHLNFLN TIRVGGYLPD RVINLLLQYL SNSISKNSMY KLLLPRLDVL LFEIVFPLMC FNDNDQKLWE EDPHEYVRKG YNIIEDLYSP RTASMDFVNE 0401: LVRKRGKENL PKFVKFVVEI FLSYEKATVE EKPYRQKDGA MLAVGALCDK LKQTDPYKSQ LELMLVQHIF PDFNSPVGHL RAKAAWVAGQ YAHINFSDQN 0501: NFRKALHSVV SGLRDPDLPV RVDSVFALRS FVEACKDLNE IRPILPQLLD EFFKLMNEVE NEDLVFTLET IVDKFGEEMA PFAFGLCQNL AAAFWRCLNT 0601: SEANDDSDDM GALAAVGCLR AISTILESVS SLPQLFVEIE PTILPIMQKM LTTDGQEVFE EVLEIASYMT FYSPSISLDI WSLWPLMVEA LVDWGIDFFP 0701: NILVPMDNFI SRGTAHFLTC KEPDYQQSLY NVLSTLMTDR NIEDSEIESA PKLIEVVFQN CKGQVDQWVE PYLRLTVDRL QRAETSYVKS LLIQVVANML 0801: YYNPGLTLGV LHNTGLASKV FDLWFQMLQQ KRKSGLPANF KREHDKKVCC LGLTSLLALP GGQFPDEALQ RVFRATLDLL VAYKNQLAEA AKETEVDYEE 0901: EMNGLQSSDD DYDDDGSDGE MDDTEEGDEA QSVKLQKLAA QAKAFHYDDD DDDDSDDDFS DEDEFQSPID EVDAFVFFVD AIRVMQASDA QRFQNLNQSL 1001: DFTYQAIANG IAQHAELRRV EIEKEKQKKL AAASTPVTAL |
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| See Also |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)