AT2G16390.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:nucleus 1.000 ASURE: nucleus What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : SNF2 domain-containing protein / helicase domain-containing protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Putative chromatin remodeling protein, member of a plant-specific subfamily of SWI2/SNF2-like proteins. Mutations nearly eliminate non-CpG methylation at a target promoter but do not affect rDNA or centromere methylation. Cooperates with PolIVb to facilitate RNA-directed de novo methylation and silencing of homologous DNA. Endogenous targets include intergenic regions near retrotransposon LTRs or short RNA encoding sequences that might epigenetically regulate adjacent genes. May be used to establish a basal yet reversible level of silencing in euchromatin. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
DEFECTIVE IN RNA-DIRECTED DNA METHYLATION 1 (DRD1); FUNCTIONS IN: helicase activity, DNA binding, ATP binding, nucleic acid binding; INVOLVED IN: DNA methylation, production of siRNA involved in RNA interference; LOCATED IN: cellular_component unknown; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: chromatin remodeling 34 (TAIR:AT2G21450.1); Has 13448 Blast hits to 11886 proteins in 1506 species: Archae - 91; Bacteria - 3564; Metazoa - 3285; Fungi - 3284; Plants - 1229; Viruses - 105; Other Eukaryotes - 1890 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr2:+:7097638..7101182 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 100235.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 5.02 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.35 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 888 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MGFVYIVMTG YYKNVHKRKQ NQVDDGPEAK RVKSSAKVID YSNPFAVSNM LEALDSGKFG SVSKELEEIA DMRMDLVKRS IWLYPSLAYT VFEAEKTMDN 101: QQVVEGVINL DDDDDDDTDV EKKALCVVPS SSEIVLLDSD DEDNERQRPM YQFQSTLVQH QKNQGDVTPL IPQCSFEEVD LGRGKEMPSA IKAIVEGQTS 201: RGKVLPIENG VVNEKGVYVG VEEDDSDNES EAADEDLGNI WNEMALSIEC SKDVARETSH KEKADVVEDC EHSFILKDDM GYVCRVCGVI EKSILEIIDV 301: QFTKAKRNTR TYASETRTKR FGESDNELKF SEEGLMIGGL AAHPTHAAEM KPHQIEGFQF LCSNLVADDP GGCIMAHAPG SGKTFMIISF MQSFLAKYPQ 401: AKPLVVLPKG ILPTWKKEFV RWQVEDIPLL DFYSAKAENR AQQLSILKQW MEKKSILFLG YQQFSTIVCD DTTDSLSCQE ILLKVPSILI LDEGHTPRNE 501: DTNLLQSLAQ VQTPRKVVLS GTLYQNHVKE VFNILNLVRP KFLKLDTSKS AVKRILAYTP CDVRGRLTGS NSDMASMFNE TVEHTLQKSE DFTVKIKVIQ 601: DLREMTKKVL HYYKGDFLDE LPGLADFTVV LNLSPKQLNE VKKLRREKRK FKVSAVGSAI YLHPKLKVFS DKSDDVSDTT MDEMVEKLDL NEGVKAKFFL 701: NLINLCDSAG EKLLVFSQYL IPLKFLERLA ALAKGWKLGK EVFVLTGNTS SEQREWSMET FNSSPDAKIF FGSIKACGEG ISLVGASRIL ILDVPLNPSV 801: TRQAIGRAFR PGQKKMVHAY RLIAGSSPEE EDHNTCFKKE VISKMWFEWN EYCGYQNFEV ETIDVDEAGD TFLESPALRE DIRVLYKR |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)