AT1G60220.1
|
Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 ASURE: nucleus What is SUBAcon? |
|||||||||||||||||||||||||||||||||||||||||||||||||||||
| Experimental Localisations and PPI |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||
|
SUBAcon links
AGI-AGI relationships |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||
| Description (TAIR10) | protein_coding : UB-like protease 1D | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a deSUMOylating enzyme. In vitro it has both peptidase activity and isopeptidase activity: it can cleave C-terminal residues from SUMO to activate it for attachment to a target protein and it can also act on the isopeptide bond between SUMO and another protein. sGFP:OTS1 protein accumulates in the nucleus. Double mutant analysis with ULP1C/OTS2 indicates that these genes are involved in salt stress responses and flowering time regulation. Over-expression of 35S:OTS1 increases salt tolerance and reduces the level of SUMO-conjugated proteins. OTS1 transcript levels do not appear to change in response to salt, but, salt stress reduces the level of OTS1 protein in a proteasome-dependent manner. | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
UB-like protease 1D (ULP1D); CONTAINS InterPro DOMAIN/s: Peptidase C48, SUMO/Sentrin/Ubl1 (InterPro:IPR003653); BEST Arabidopsis thaliana protein match is: Cysteine proteinases superfamily protein (TAIR:AT1G10570.2); Has 2556 Blast hits to 2339 proteins in 246 species: Archae - 0; Bacteria - 12; Metazoa - 1276; Fungi - 441; Plants - 318; Viruses - 13; Other Eukaryotes - 496 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||
| Coordinates (TAIR10) | chr1:+:22208332..22211910 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 67194.80 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 5.82 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.88 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 584 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MTKRKKEVID VDCSEKKDFV IDWSSAMDKE DEVPELEIVN TTKPTPPPPP TFFSDDQTDS PKLLTDRDLD EQLERKKAIL TLGPGLPDKG EKIRLKIADL 101: EEEKQRRVLE GSKMEVDRSS KVVSSTSSGS DVLPQGNAVS KDTSRGNADS KDTSRQGNAD SKEVSRSTFS AVFSKPKTDS QSKKAFGKEL EDLGCERRKH 201: KAGRKPVTRL SNGWRLLPDV GKAEHSAKQF DSGLKESKGN KKSKEPYGKK RPMESSTYSL IDDDDDDDDD DDNDTSGHET PREWSWEKSP SQSSRRRKKS 301: EDTVINVDEE EAQPSTVAEQ AAELPEGLQE DICYPTRDDP HFVQVCLKDL ECLAPREYLT SPVMNFYMRF LQQQISSSNQ ISADCHFFNT YFYKKLSDAV 401: TYKGNDKDAF FVRFRRWWKG IDLFRKAYIF IPIHEDLHWS LVIVCIPDKK DESGLTILHL DSLGLHSRKS IVENVKRFLK DEWNYLNQDD YSLDLPISEK 501: VWKNLPRRIS EAVVQVPQQK NDFDCGPFVL FFIKRFIEEA PQRLKRKDLG MFDKKWFRPD EASALRIKIR NTLIELFRVS DQTE |
||||||||||||||||||||||||||||||||||||||||||||||||||||
| See Also |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||
Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)