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AT3G12280.2
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 0.908
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : retinoblastoma-related 1
Curator
Summary (TAIR10)
Encodes a retinoblastoma homologue RETINOBLASTOMA-RELATED protein (RBR or RBR1). RBR controls nuclear proliferation in the female gametophyte. Also required for correct differentiation of male gametophytic cell types. Regulates stem cell maintenance in Arabidopsis roots. Involved in the determination of cell cycle arrest in G1 phase after sucrose starvation. RBR1 is also involved in regulation of imprinted genes. Together with MSI1 it represses the expression of MET1. This in turn activates expression of the imprinted genes FIS2 and FWA.
Computational
Description (TAIR10)
retinoblastoma-related 1 (RBR1); FUNCTIONS IN: transcription factor binding; INVOLVED IN: in 15 processes; LOCATED IN: cytosol; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Retinoblastoma-associated protein, B-box (InterPro:IPR002719), Cyclin-like (InterPro:IPR011028), Cyclin-related (InterPro:IPR013763), Retinoblastoma-associated protein, A-box (InterPro:IPR002720).
Protein Annotations
eggNOG:ENOG410XQF7eggNOG:KOG1010EMBL:CP002686EnsemblPlants:AT3G12280
EnsemblPlants:AT3G12280.2entrez:820408ExpressionAtlas:F4J8Q4Gene3D:1.10.472.10
GeneID:820408GO:GO:0005634GO:GO:0006351GO:GO:0006357
GO:GO:0007049GO:GO:0051726Gramene:AT3G12280.2hmmpanther:PTHR13742
hmmpanther:PTHR13742:SF17InterPro:IPR002719InterPro:IPR002720InterPro:IPR013763
InterPro:IPR015652InterPro:IPR024599InterPro:IPR028309KEGG:ath:AT3G12280
KO:K04681PANTHER:PTHR13742PANTHER:PTHR13742:SF17PaxDb:F4J8Q4
Pfam:PF01857Pfam:PF01858Pfam:PF11934PRIDE:F4J8Q4
ProteinModelPortal:F4J8Q4Proteomes:UP000006548RefSeq:NP_001189868.1SMART:SM01367
SMART:SM01368STRING:3702.AT3G12280.1SUPFAM:SSF47954TAIR:AT3G12280
tair10-symbols:RBR1UniGene:At.14958UniProt:F4J8Q4
Coordinates (TAIR10) chr3:-:3913671..3918433
Molecular Weight (calculated) 112094.00 Da
IEP (calculated) 7.96
GRAVY (calculated) -0.20
Length 1012 amino acids
Sequence (TAIR10)
(BLAST)
0001: MEEVQPPVTP PIEPNGKRSE ASLLDICEKV LSLDGSTCDE ALKLFTETKR ILSASMSNIG SGTREEVERF WFAFILYSVK RLSVRKEADG LSVSGDNEFN
0101: LCQILRALKL NIVDFFKELP QFVVKAGSVL GELYGADWEN RLQAKEVQAN FVHLSLLSKY YKRGFREFFL TYDANAEKNS ANSSTYLLDS YRFGWLLFLA
0201: LRNHAFSRFK DLVTCSNGVV SILAILIIHV PCRFRNFSIQ DSSRFVKKGD KGVDLVASLC KIYDASEDEL RIVIDKANNL VETILKKKPS PASECQTDKL
0301: DNIDPDGLTY FEDLLEETSI STSLITLEKD YYDGKGELDE RVFINEEDSL LGSGSLSAGA VNITGVKRKI DALSSPARTF ISPLSPHKSP AAKTNGISGA
0401: TKLAATPVST AMTTAKWLRT VISPLLPKPS PGLEHFLKSC DRDITNDVTR RAHIILEAIF PNSSLGAQCG GGSLQAVDLM DDIWAEQRRL EACKLYYRVL
0501: EAMCKAEAQI LHANNLNSLL TNERFHRCML ACSAELVLAT HKTITMLFPA VLERTGITAF DLSKVIESFI RHEDSLPREL RRHLNSLEER LLESMVWEKG
0601: SSMYNSLIVA RPSLALEINQ LGLLAEPMPS LDAIAALINF SDGANHASSV QKHETCPGQN GGIRSPKRLC TDYRSILVER NSFTSPVKDR LLALGNVKSK
0701: MLPPPLQSAF ASPTRPNPGG GGETCAETGI NIFFTKINKL AAVRINGMVE RLQLSQQIRE SVYCFFQHVL AQRTSLLFSR HIDQIILCCF YGVAKISQMS
0801: LTFREIIYNY RKQPQCKPLV FRSVYVDALQ CRRQGRIGPD HVDIITFYNE IFIPAVKPLL VELGPVRNDR AVEANNKPEG QCPGSPKVSV FPSVPDMSPK
0901: KVSAVHNVYV SPLRGSKMDA LISHSTKSYY ACVGESTHAY QSPSKDLSAI NNRLNNSSNR KRTLNFDAEA GMVSDSMVAN SLNLQNQNQN QNGSDASSSG
1001: GAAPLKTEPT DS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)