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AT2G31970.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : DNA repair-recombination protein (RAD50)
Curator
Summary (TAIR10)
Encodes the Arabidopsis RAD50 homologue. It is involved in double strand break repair. Component of the meiotic recombination complex that processes meiotic double-strand-breaks to produce single-stranded DNA ends, which act in the homology search and recombination. Accumulates in the nucleus during meiotic prophase, a process regulated by PHS1.
Computational
Description (TAIR10)
RAD50; FUNCTIONS IN: zinc ion binding, ATP binding, nuclease activity; INVOLVED IN: DNA repair, double-strand break repair, telomere capping, mitotic recombination, telomere maintenance; LOCATED IN: nucleus, Mre11 complex, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Zinc hook, Rad50 (InterPro:IPR013134), Rad50 zinc hook (InterPro:IPR007517), Recombination/repair protein Rad50 (InterPro:IPR004584); Has 105617 Blast hits to 56308 proteins in 2913 species: Archae - 1820; Bacteria - 19240; Metazoa - 45759; Fungi - 8381; Plants - 4805; Viruses - 470; Other Eukaryotes - 25142 (source: NCBI BLink).
Protein Annotations
EC:3.6.-.-eggNOG:COG0419eggNOG:KOG0962EMBL:AC006223EMBL:AF168748EMBL:AY139771EMBL:BT005823
EMBL:CP002685EnsemblPlants:AT2G31970EnsemblPlants:AT2G31970.1entrez:817756Gene3D:3.40.50.300GeneID:817756Genevisible:Q9SL02
GO:GO:0000723GO:GO:0000781GO:GO:0005524GO:GO:0005634GO:GO:0005737GO:GO:0006302GO:GO:0006312
GO:GO:0016233GO:GO:0016887GO:GO:0030870GO:GO:0046872GO:GO:0051321Gramene:AT2G31970.1hmmpanther:PTHR18867
hmmpanther:PTHR18867:SF12HOGENOM:HOG000264309InParanoid:Q9SL02InterPro:IPR004584InterPro:IPR013134InterPro:IPR027417iPTMnet:Q9SL02
KEGG:ath:AT2G31970KO:K10866ncoils:CoilOMA:RSMVCTQPANTHER:PTHR18867PaxDb:Q9SL02Pfam:PF04423
Pfam:PF13476Pfam:Q9SL02Pfscan:PS51131PhylomeDB:Q9SL02PIR:D84727PRIDE:Q9SL02PRO:PR:Q9SL02
PROSITE:PS51131ProteinModelPortal:Q9SL02Proteomes:UP000006548Reactome:R-ATH-2559586Reactome:R-ATH-5685939Reactome:R-ATH-5693548Reactome:R-ATH-5693565
RefSeq:NP_565733.1SMR:Q9SL02STRING:3702.AT2G31970.1SUPFAM:SSF52540TAIR:AT2G31970tair10-symbols:ATRAD50tair10-symbols:RAD50
TIGRfam:TIGR00606TIGRFAMs:TIGR00606UniGene:At.65745UniProt:Q9SL02
Coordinates (TAIR10) chr2:+:13600657..13608815
Molecular Weight (calculated) 152823.00 Da
IEP (calculated) 6.21
GRAVY (calculated) -0.80
Length 1316 amino acids
Sequence (TAIR10)
(BLAST)
0001: MSTVDKMLIK GIRSFDPENK NVVTFFRPLT LIVGANGAGK TTIIECLKVS CTGELPPNAR SGHSFIHDPK VAGETETKAQ IKLRFKTAAG KDVVCIRSFQ
0101: LTQKASKMEY KAIESVLQTI NPHTGEKVCL SYRCADMDRE IPALMGVSKA ILENVIFVHQ DESNWPLQDP STLKKKFDDI FSATRYTKAL EVIKKLHKDQ
0201: AQEIKTFKLK LENLQTLKDA AYKLRESIAQ DQERTESSKV QMLELETSVQ KVDAEVHNKE MMLKDLRKLQ DQVSIKTAER STLFKEQQRQ YAALPEENED
0301: TIEELKEWKS KFEERLALLG TKIRKMEREM VDTETTISSL HNAKTNYMLE ISKLQTEAEA HMLLKNERDS TIQNIFFHYN LGNVPSTPFS TEVVLNLTNR
0401: IKSRLGELEM DLLDKKKSNE TALSTAWDCY MDANDRWKSI EAQKRAKDEI KMGISKRIEE KEIERDSFEF EISTVDVKQT DEREKQVQVE LERKTKQNSE
0501: RGFESKIEQK QHEIYSLEHK IKTLNRERDV MAGDAEDRVK LSLKKTEQEN LKKKHKKIID ECKDRIRGVL KGRLPPEKDM KREIVQALRS IEREYDDLSL
0601: KSREAEKEVN MLQMKIQEVN NSLFKHNKDT ESRKRYIESK LQALKQESVT IDAYPKLLES AKDKRDDRKR EYNMANGMRQ MFEPFEKRAR QEHSCPCCER
0701: SFTADEEASF IKKQRVKASS TGEHLKALAV ESSNADSVFQ QLDKLRAVFE EYSKLTTEII PLAEKTLQEH TEELGQKSEA LDDVLGISAQ IKADKDSIEA
0801: LVQPLENADR IFQEIVSYQK QIEDLEYKLD FRGLGVKTME EIQSELSSLQ SSKDKLHGEL EKLRDDQIYM ERDISCLQAR WHAVREEKAK AANLLRDVTK
0901: AEEDLERLAE EKSQLDLDVK YLTEALGPLS KEKEQLLSDY NDMKIRRNQE YEELAEKKRN YQQEVEALLK ASYKINEYHD LKKGERLDDI QEKQRLSDSQ
1001: LQSCEARKNE LAGELNRNKD LMRNQDQLRR NIEDNLNYRT TKAKVEELTR EIESLEEQIL NIGGIAAVEA EIVKILRERE RLLSELNRCR GTVSVYESSI
1101: SKNRVELKQA QYKDIDKRHF DQLIQLKTTE MANKDLDRYY NALDKALMRF HTMKMEEINK IIRELWQQTY RGQDMDYIRI HSDSEGAGTR SYSYKVLMQT
1201: GDTELEMRGR CSAGQKVLAS LIIRLALAET FCLNCGILAL DEPTTNLDGP NSESLAGALL RIMEDRKGQE NFQLIVITHD ERFAQMIGQR QHAEKYYRVA
1301: KDDMQHSIIE AQEIFD
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)