AT3G48190.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : ataxia-telangiectasia mutated | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
encodes a homolog of the human ATM gene, which is mutated in ataxia telangiectasia, a chromosome instability disorder. Characterization of mutants suggest a role in repairing DNA in response to ionizing radiation as well as during meiosis. The protein has kinase domains and shows kinase activity in orthologs. There is also evidence that ATM might be involved in the telomerase-independent process known as Alternative Lengthening of Telomeres. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
ataxia-telangiectasia mutated (ATM); FUNCTIONS IN: 1-phosphatidylinositol-3-phosphate 5-kinase activity; INVOLVED IN: in 8 processes; LOCATED IN: chloroplast; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic (InterPro:IPR000403), PIK-related kinase, FAT (InterPro:IPR003151), Ataxia-Telangiectasia Mutated (InterPro:IPR015519), PIK-related kinase (InterPro:IPR014009), PWWP (InterPro:IPR000313), PIK-related kinase, FATC (InterPro:IPR003152), Phosphatidylinositol 3/4-kinase, conserved site (InterPro:IPR018936), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: Ataxia telangiectasia-mutated and RAD3-related (TAIR:AT5G40820.1); Has 3479 Blast hits to 3364 proteins in 268 species: Archae - 0; Bacteria - 7; Metazoa - 1400; Fungi - 858; Plants - 531; Viruses - 0; Other Eukaryotes - 683 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr3:+:17797628..17828361 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 433789.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 7.22 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.20 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 3845 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MKLQNPDKKT LREGFSQESS VVALDSGVLA MSGLKCDGKF PVKDVLMEEG GDKVRKIQVS GGNISLVVDF SGARTSSNNF FESNASCVNE NLVKGNGYRE 0101: DETQEFLVGN LVWVMTKYKK WWPGEVVDFK ADAKESFMVR SIGQSHLVSW FASSKLKPFK ESFEQVLNQR NDNGFFDALQ KAMSLLSNSL KLDMTCSCIA 0201: DGNGIVSAQN ITTRKNKPLI LREFSVDRLE PKEFVTQLKN IAKCVLNAGV LESTVMQSQL SAFYTLFGHK QIPMAQLHEN EGRKSFTAKM SDSKFIGSPS 0301: ICAGNSRKRF RKEWFRKFVS EVDNVSARDD LVNVPPSDLI SKLKLLAVGY NCSEETENIG LFEWFFSKFR ISVYHDENAY KMQLANMAGF KDLMLATNAN 0401: RGTVQKTLKS KKIGKSKMEP LNGVSVADTE QKTFELQISK KSNIESLNGV SVADTEQKTF ELQILEKSNI ESLNGVSTPN IDHEASKSNN SGKTKINHII 0501: GHSNFPSSVA KVQLAKDFQD KLLVQAPDRK AMTADTLSRP AAILVPDLNS GGNALGTAEF DHMQRPETLI QHNVCPQEEK TPRSTILNFQ VTAHQGVSGT 0601: QFVSSQPTSY KHFTSADLFT YSGKKKRGRK RKNAEELPIV AHASATTGIP DLNGTNTEPT LVLPQVEPTQ RRRRRKKEES PNGLTRGITI LFLKFSSQVS 0701: MPSRDDLTST FSAFGPLDSS ETHVSEEFSG AQVAFVSSAD AIEAVKSLEK ANPFGETLVN FRLQQKLITV QRNIAPRMPV ISHVSPVPKP NNIPTSMDAM 0801: RQNLLMMTAM LEKSGDSLSR ETKAKLKSEI TGLLEKDGVK LLNTWLEGER SITFCRFLSQ NTAKLKLDEI PNAETWPFLV KLLLQCVSME VSGSKRRMPK 0901: PTFAKTLRVV VQRTEETKFP GVQFPLLSMA KTLFTHVHDI LSNTPSFQSE YGTILRHLLE IKEYRFQMRK RTYSSLVLLY MERAETGFCE KNSGQHSQKE 1001: EAFRYILTLQ SLLENSPGDF PDDLREEIVN GLIHIFSSVR DEGKLSRKLI ECVNTFLLKD GPNLGSLSLE IHNAVEQFVF RCWLTTHDKN LKEILVSYGR 1101: LQLNLTRDSS ESSSLVEQLL DVVTRELDLG SSSSSASWGD TTKDEKLGAL SSYQNSLVEL AAHVFYRACV NTSRPSLSEK RARRQHIAMR MVDALTEGKW 1201: LWCAAFGCLV RNYCARINMD LLIYWFEAIC TNFQRLLEDA SMRRSYDGLL WTLRSLQGLS SGLSLPDITM DISKSSASSS ELDRGWQSIW SSLIHGLATF 1301: SSMSVIVDAV LVLLGSIISS NHITVKILPQ EVWDHQLFRH IPSEPALYFI ACYFSRMGCQ GNLQDDLHLR RNLLRAVCAP LSWKVRLTLD ERMVQLLPAA 1401: AFSLCAGFKV SLPLPKEHLP TPSQWDVCEQ IDDVDRERNF GLFECSVEAL TRICSNSSKI SGCQVPDVVQ LPLVLRDPLL HDMDIYFLSI IPEVKEKGPL 1501: SDIFMGCALL CHFMHGSYIT RKGKGSSSFF LKACQYLLEG LDHAVESVSK SLNDLQRRGS LGFGSDFNEK GSIIVSLRSF TQSPVFSNRR DQNLLGASYD 1601: FVIHSLENLL RSFAKVYEEY TEHAWNTHSD TVPSKSLAPD SPEVGRIVDM DLDLAEDTKE RDIIAAGGKA VPGLPVSMGN WKLGMVSLIS CFSPVLQFPT 1701: WDVLYNLLEK ESDPKVLENI LYHLCKLSCL TSIPKVDDLV IFLDGMLSTQ VKMKRNCLNI VTALHVLLHT LSSSRRDSSG VEKNCGLSLK EAESFQVFVQ 1801: LGAMVNKVSE FGLLGWFGRV KLINCICDLV LLNPQTGQTM IERLLLMLSD SDYRVRFVLA RQIGILFQTW DGHEALFQDI CSSFGIKLVT SSKEKLVTAK 1901: DVLAVGPQPR QKMETVIITL MHLAYHSENI ELQAVFMMCA VSAKDPCQRE LIIAALDNLS AQLHYPSRFK YLEELLGPIL FHWIASGVSL AGLIETSQLF 2001: IPNAEPKYFI HFCSHWLLPA LLLHEDHTNL DWVAKMAGQP VVVLVKENFV PIFSICMGLH CSKTSECDKG AMVLQNSILY VGETSENERD KLIKQNMVSI 2101: VSFILSCASS SPEPPVPTFS RDTISLAVQT VVDGFLENTD YPKNAAITDR INIFRPDRVF MFITEMHYRM SAACHHRHTR HHLAALEELT ILLGHRALVP 2201: SSLNYIFNLV GQFIGYPSLQ DQCCSIASCL LDLFKSNPAK EIVSVLGDQL QFLVSKLVTC CIDAEADTKI SGAKSSQLVN LLHKLVVSSD SSLNEDIRDL 2301: EPLPDLKYFQ VIRESHIRIC EAYSPRNHLL KVEHSTFLIY IFLEILSLSN FLFLSCSTIQ QCSRRSNYLP PRFLSRSLQA LHNKLIASEV SQEDTNGETA 2401: ETFWQSDDEI VNAVWTLVRV SASDEADSMR LLVSDFLSRI GIRDPHTVVF HLPGNLVSMH GLQGFGHNTG SKVRSLTENG ISDETLITLL NFLKKYLLDD 2501: SVKIIDVTSQ TLRGILSTER GQQALSSFDS CERALIEVHG RGVNLDIVEK ILLDSQKQFK AEKFSLETPE VWSTDNKNFD RWICQLVYCM IALCEDVPIR 2601: LCQNIALLKA EISELLFPSV VVSLAGRIGM DINLHDLITS QVKEHIFTDS NKLTKSKQVM LNTLNELRMC YVLERSIFSG QTKREKNSRS CSTAAKIRDV 2701: ESGSNGMAAS ITTNWEKVYW LSIDYLVVAG SAVVCGAYLT ASMYVEYWCE EKFGNLSLGD PDFSYHDKLP DHVEILVSAI TRINEPDSLY GVIHSNKLSA 2801: QIITFEHEGN WTRALEYYDL QARSQKMVVP SSLSENLEVE QFQPTTSARH SVFGEGEVQR QPFKGLIRSL QQTGCMHVLD LYCRGLTSRE GCFQYDPEFI 2901: ELQYEAAWRA GKWDFSLLYP QTHCQPLQHA KNNNYHESLH CCLRALQEGD YDGFYGKLKD TKKELVLSIS RASEESTEFI YSTVVKLQIL HHLGLVWDLR 3001: WTTSSHQSVH GYLVKQMACV DPVIPTMDQL SWLNKDWNSI ITQTQLHMTL LEPFIAFRRV LLQILGCEKC TMQHLLQSAS LLRKGTRFSH AAASLHEFKF 3101: LCARSNGQQP VPDWLGKLEE AKLLHAQGRH EVSISLANYI LHNYQLKEEA SDIYRVIGKW LAETRSSNSR TILEKYLRPA VSLAEEQSSK ICKRLVDRQS 3201: QTWFHLAHYA DALFKSYEER LSSSEWQAAL RLRKHKTKEL EAEQSDYSLK IQDLQKQLTM DKEEAEKLQV DRDNFLKLAL EGYKRCLEIG DKYDVRVVFR 3301: QVSMWFSLAS QKNVIDNMLS TIKEVQSYKF IPLVYQIASR LGSSKDESGS NSFQSALVSL IRKMAIDHPY HTILQLLALA NGDRIKDNQR SRNSFVVDMD 3401: KKLAAEHLLQ DVSHYHGPMI RQMKQLVDIY IKLAELETRR EDTNRKVALP REIRSVKQLE LVPVVTATIP VDRSCQYNEG SFPFFRGLSD SVTVMNGINA 3501: PKVVECFGSD GQKYKQLAKS GNDDLRQDAV MEQFFGLVNT FLHNNRDTWK RRLAVRTYKV IPFTPSAGVL EWVDGTIPLG DYLIGSSRSE GAHGRYGIGN 3601: WKYPKCREHM SSAKDKRKAF VDVCTNFRPV MHYFFLEKFL QPADWFVKRL AYTRSVAASS MVGYIVGLGD RHAMNILIDQ ATAEVVHIDL GVAFEQGLML 3701: KTPERVPFRL TRDIIDGMGI TGVEGVFRRC CEETLSVMRT NKEALLTIVE VFIHDPLYKW ALSPLKALQR QKETEDYDGM NLEGLQEEFE GNKDATRALM 3801: RVKQKLDGYE GGEMRSIHGQ AQQLIQDAID TDRLSHMFPG WGAWM |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)