suba logo
AT3G21230.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

.
SUBAcon:
peroxisome 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : 4-coumarate:CoA ligase 5
Curator
Summary (TAIR10)
The gene encodes a 4-coumarate coenzyme A ligase being able to use sinapate as substrate. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, 5-OH-ferulic acid, ferulic acid and sinapic acid. At4CL5 was unable to use cinnamic acid as substrate. Knockout of At4CL5 (4cl5) revealed no effect on syringyl lignin content indicating that the activity observed does probably not occur in vivo.
Computational
Description (TAIR10)
4-coumarate:CoA ligase 5 (4CL5); CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: 4-coumarate:CoA ligase 2 (TAIR:AT3G21240.1); Has 86695 Blast hits to 79061 proteins in 3832 species: Archae - 1152; Bacteria - 55057; Metazoa - 3672; Fungi - 4648; Plants - 2823; Viruses - 1; Other Eukaryotes - 19342 (source: NCBI BLink).
Protein Annotations
EC:6.2.1.12eggNOG:COG0318eggNOG:KOG1176EMBL:AB023045
EMBL:AY095992EMBL:AY250837EMBL:AY376732EMBL:BT000614
EMBL:CP002686EnsemblPlants:AT3G21230EnsemblPlants:AT3G21230.1entrez:821677
GeneID:821677Genevisible:Q9LU36GO:GO:0005524GO:GO:0009699
GO:GO:0016207Gramene:AT3G21230.1gramene_pathway:6.2.1.12gramene_pathway:PWY-1121
gramene_pathway:PWY-361gramene_pathway:PWY-5868gramene_pathway:PWY1F-FLAVSYNgramene_pathway:PWY4FS-9
hmmpanther:PTHR24096hmmpanther:PTHR24096:SF149HOGENOM:HOG000230009InParanoid:Q9LU36
InterPro:IPR000873InterPro:IPR020845InterPro:IPR025110iPTMnet:Q9LU36
KEGG:ath:AT3G21230KO:K01904OMA:SMIRAFDPaxDb:Q9LU36
Pfam:PF00501Pfam:PF13193Pfam:Q9LU36PhylomeDB:Q9LU36
PRIDE:Q9LU36PRO:PR:Q9LU36PROSITE:PS00455ProteinModelPortal:Q9LU36
Proteomes:UP000006548Reactome:R-ATH-75105RefSeq:NP_188760.3SABIO-RK:Q9LU36
scanprosite:PS00455SMR:Q9LU36STRING:3702.AT3G21230.1SUPFAM:SSF56801
TAIR:AT3G21230tair10-symbols:4CL5UniGene:At.38095UniPathway:UPA00372
UniProt:Q9LU36
Coordinates (TAIR10) chr3:-:7448231..7451947
Molecular Weight (calculated) 62562.70 Da
IEP (calculated) 5.54
GRAVY (calculated) -0.03
Length 570 amino acids
Sequence (TAIR10)
(BLAST)
001: MVLQQQTHFL TKKIDQEDEE EEPSHDFIFR SKLPDIFIPN HLPLTDYVFQ RFSGDGDGDS STTCIIDGAT GRILTYADVQ TNMRRIAAGI HRLGIRHGDV
101: VMLLLPNSPE FALSFLAVAY LGAVSTTANP FYTQPEIAKQ AKASAAKMII TKKCLVDKLT NLKNDGVLIV CLDDDGDNGV VSSSDDGCVS FTELTQADET
201: ELLKPKISPE DTVAMPYSSG TTGLPKGVMI THKGLVTSIA QKVDGENPNL NFTANDVILC FLPMFHIYAL DALMLSAMRT GAALLIVPRF ELNLVMELIQ
301: RYKVTVVPVA PPVVLAFIKS PETERYDLSS VRIMLSGAAT LKKELEDAVR LKFPNAIFGQ GYGMTESGTV AKSLAFAKNP FKTKSGACGT VIRNAEMKVV
401: DTETGISLPR NKSGEICVRG HQLMKGYLND PEATARTIDK DGWLHTGDIG FVDDDDEIFI VDRLKELIKF KGYQVAPAEL EALLISHPSI DDAAVVAMKD
501: EVADEVPVAF VARSQGSQLT EDDVKSYVNK QVVHYKRIKM VFFIEVIPKA VSGKILRKDL RAKLETMCSK
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)