AT3G10800.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:endoplasmic reticulum 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Basic-leucine zipper (bZIP) transcription factor family protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes bZIP28, a putative membrane-tethered transcriptional factor. Up-regulated in response to heat; a bZIP28 null mutant has a heat-sensitive phenotype. bZIP28 has a similar domain structure to the mammalian ATF6 protein involved in the unfolded protein response (UPR), and shares a bZIP domain, transmembrane domain, and a canonical S1P cleavage site. The bZIP28 seems to be glycosylated in vivo. bZIP28 does not appear to be transcriptionally up-regulated by UPR-inducing tunicamycin (TM) treatment. But, the expression level of three UPR-related genes is reduced in TM-treated zip28 mutants relative to wild type seedlings. And several UPR genes are transcriptionally upregulated when an N-terminal portion of the bZIP28 protein is expressed using the 35S promoter. A myc:bZIP28 fusion protein appears to be cleaved, likely at a canonical S2 cleavage site, following a TM treatment or a DTT stress-inducing treatment, but not a salt treatment. A portion of the mGFP:bZIP28 protein present in root cells appears to translocate from the cytoplasm and ER to the nucleus following TM treatment. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
BZIP28; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: Basic-leucine zipper (bZIP) transcription factor family protein (TAIR:AT2G40950.1); Has 1906 Blast hits to 1391 proteins in 215 species: Archae - 0; Bacteria - 248; Metazoa - 700; Fungi - 222; Plants - 463; Viruses - 4; Other Eukaryotes - 269 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr3:+:3379326..3381430 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 73436.40 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.41 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.48 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 675 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MTESTSVVAP PPEIPNLNPS MFSESDLFSI PPLDPLFLSD SDPISMDAPI SDLDFLLDDE NGDFADFDFS FDNSDDFFDF DLSEPAVVIP EEIGNNRSNL 101: DSSENRSGDG GLEGRSESVH SQVSSQGSKT FVSDTVDASS SPESSNHQKS SVSKRKKENG DSSGELRSCK YQKSDDKSVA TNNEGDDDDD KRKLIRQIRN 201: RESAQLSRLR KKQQTEELER KVKSMNATIA ELNGKIAYVM AENVALRQQM AVASGAPPMN PYMAAPPLPY QWMPYPPYPV RGYGSQTPLV PIPKLNPKPV 301: SSCRPKKAES KKNEGKSKLK KVASISFIGI LFFVFLFGTL VPFMNVNFGG ERGSFGGLSK YDGHRYYDEH KGRVLMVGDG SDVRRNSGIS EGNIHSSRIS 401: HGERDSCGGV DYNAHPKVEG RPSSLSNASD PLFASLYVPR NDGLVKIDGN LIIHSVLASE KARGLGKKNI TETVKTKEPD LTIPGALSSA LAVPGVRGNA 501: AMLPHSTALS SEGKRLHQWF HEGGSGPLMD YSMCTEVFQF DIAPGAIVPS SVSSISAEHL QNVTTHGKRM KNRRILEGLP VSLVASELNI TGTQPNKDAQ 601: NKTFNGNTNK PTSSSSMVVS VLLDPREVVD SETDRVVPPN PKSLSRIFVV VLLDSVKYVT YSCVLPRSGL HLVAT |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)