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AT5G63920.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : topoisomerase 3alpha
Curator
Summary (TAIR10)
Encodes topoisomerase 3alpha. Suppresses somatic crossovers. Essential for resolution of meiotic recombination intermediates.
Computational
Description (TAIR10)
topoisomerase 3alpha (TOP3A); FUNCTIONS IN: DNA topoisomerase activity, DNA topoisomerase type I activity, DNA binding, zinc ion binding, nucleic acid binding; INVOLVED IN: in 7 processes; LOCATED IN: chromosome; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA topoisomerase, type IA, zn finger (InterPro:IPR013498), DNA topoisomerase, type IA, core (InterPro:IPR000380), DNA topoisomerase, type IA, domain 2 (InterPro:IPR003601), DNA topoisomerase, type IA, DNA-binding (InterPro:IPR003602), DNA topoisomerase, type IA, central (InterPro:IPR013497), Zinc finger, GRF-type (InterPro:IPR010666), DNA topoisomerase, type IA, central region, subdomain 3 (InterPro:IPR013826), Toprim domain, subgroup (InterPro:IPR006154), DNA topoisomerase, type IA, central region, subdomain 1 (InterPro:IPR013824), Toprim domain (InterPro:IPR006171), Zinc finger, CCHC-type (InterPro:IPR001878); BEST Arabidopsis thaliana protein match is: DNA topoisomerase, type IA, core (TAIR:AT2G32000.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G63920-MONOMEREC:5.99.1.2eggNOG:COG0550eggNOG:KOG1956
EMBL:AB019227EMBL:CP002688EMBL:EU295446EnsemblPlants:AT5G63920
EnsemblPlants:AT5G63920.1entrez:836513Gene3D:1.10.290.10Gene3D:1.10.460.10
Gene3D:3.40.50.140GeneID:836513Genevisible:Q9LVP1GO:GO:0000712
GO:GO:0003677GO:GO:0003917GO:GO:0005694GO:GO:0006265
GO:GO:0006281GO:GO:0007059GO:GO:0007067GO:GO:0007126
GO:GO:0008270Gramene:AT5G63920.1hmmpanther:PTHR11390hmmpanther:PTHR11390:SF21
HOGENOM:HOG000184377InParanoid:Q9LVP1InterPro:IPR000380InterPro:IPR001878
InterPro:IPR003601InterPro:IPR003602InterPro:IPR006171InterPro:IPR010666
InterPro:IPR013497InterPro:IPR013498InterPro:IPR013824InterPro:IPR013826
InterPro:IPR023405InterPro:IPR023406KEGG:ath:AT5G63920KO:K03165
OMA:QHLGRPNPANTHER:PTHR11390PaxDb:Q9LVP1Pfam:PF01131
Pfam:PF01396Pfam:PF01751Pfam:PF06839Pfam:Q9LVP1
Pfscan:PS50158Pfscan:PS50880PhylomeDB:Q9LVP1PRIDE:Q9LVP1
PRINTS:PR00417PRO:PR:Q9LVP1PROSITE:PS00396PROSITE:PS50158
PROSITE:PS50880ProteinModelPortal:Q9LVP1Proteomes:UP000006548RefSeq:NP_201197.1
scanprosite:PS00396SMART:SM00343SMART:SM00436SMART:SM00437
SMART:SM00493SMR:Q9LVP1STRING:3702.AT5G63920.1SUPFAM:SSF56712
SUPFAM:SSF57756TAIR:AT5G63920tair10-symbols:AtTOP3alphatair10-symbols:TOP3A
UniGene:At.28974UniProt:Q9LVP1
Coordinates (TAIR10) chr5:+:25574533..25581230
Molecular Weight (calculated) 103413.00 Da
IEP (calculated) 7.51
GRAVY (calculated) -0.52
Length 926 amino acids
Sequence (TAIR10)
(BLAST)
001: MSRRGGGPVT VLNVAEKPSV AKSVAGILSR GTFRTREGRS RYNKIFEFDY AINGQPCRML MTSVIGHLME LEFADRYRKW HSCDPADLYQ APVMKHVPED
101: KKDIKKTLEE EARKSDWLVL WLDCDREGEN IAFEVVDVCR AVKHNLFIRR AHFSALIDRD IHEAVQNLRD PNQLFAEAVD ARQEIDLRIG ASFTRFQTML
201: LRDRFAIDST GEERSRVISY GPCQFPTLGF IVERYWEIQA HEPEEFWTIN CSHQSEEGLA TFNWMRGHLF DYASAVILYE MCVEEPTATV MNVPHPRERF
301: KYPPYPLNTI ELEKRASRYF RLSSEHTMKV AEELYQAGFI SYPRTETDSF SSRTDLRAMV EEQTRHPAWG SYAQRLLEPE GGLWRNPANG GHDDKAHPPI
401: HPTKFSSGES NWSRDHLNVY ELVVRHYLAC VSQPAVAAET TVEIDIAGER FSASGRAILA KNYLEVYRFE SWGGSVIPVY EKGQQFIPTT LTLDAAVTRP
501: PPLLCEADLL SCMDKAGIGT DATMHDHIKK LLDRGYATKD ANTRFSPTNL GEALVMGYDD MGYELWKPNL RALMEHDMNE VSVGRKTKAE VLETCLQQMK
601: ACFLDARVKK SKLLEAMTIF FERSNNTDES ESQTAGEVVR RCNLCNESDM ALRKNRDGNF MVGCMNYPQC RNAVWLPGPT LEASVTTNVC QSCGPGPVYK
701: ILFKFRQIGI PPGFDVNHLG CVGGCDDILK QLIDICGTGS RSQARRTPGT APSNNIQGSN TRQSNVCIHC QQRGHASTNC PSRVPASRNS RPTATNPRND
801: ESTVSCNTCG SQCVLRTANT EANRGRQFFS CPTQGCSFFA WEDSINNSSG NATTGSNSGG SGRRGSRGRG RGGRGGQSSG GRRGSGTSFV SATGEPVSGI
901: RCFSCGDPSH FANACPNRNN SNGNYF
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)