AT5G41360.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:nucleus 1.000 ASURE: nucleus What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : homolog of Xeroderma pigmentosum complementation group B 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes XPB2, a DNA repair protein and transcription factor. Arabidopsis thaliana has duplicated XPB gene (AtXPB1 and AtXPB2, with high similarity to each other). XPB proteins are involved in both DNA repair and transcription, they are component of the transcription factor IIH (TFIIH) and are responsible for DNA helicase activity during nucleotide (nt) excision repair (NER). Complementation assays in yeast rad25 mutant strains suggest the involvement of AtXPB2 in DNA repair. Although both genes are expressed in a constitutive manner during the plant life cycle, Northern blot analyses suggest that light modulates the expression level of both XPB copies. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
homolog of Xeroderma pigmentosum complementation group B 2 (XPB2); FUNCTIONS IN: in 7 functions; INVOLVED IN: response to UV-B, N-terminal protein myristoylation; EXPRESSED IN: whole plant; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Restriction endonuclease, type I, R subunit/Type III, Res subunit (InterPro:IPR006935), DEAD-like helicase, N-terminal (InterPro:IPR014001), Xeroderma pigmentosum group B protein (XP-B) (InterPro:IPR001161), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: homolog of xeroderma pigmentosum complementation group B 1 (TAIR:AT5G41370.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr5:+:16544574..16549121 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 86740.70 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 8.17 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.54 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 766 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MGNDERKRPT KKMKYGGKDD QKMKNIQNVE DYYDDADEDS RDGEGEEKRR DFTDLELKPD HGNRPLWACA DGKIFLETFS PLYKQAYDFL IAIAEPVCRP 101: ESMHEYNLTP HSLYAAVSVG LETETIISVL NKLSKTKLPG EIIDFIHAST ANYGKVKLVL KKNRYFIESP FPEVLKRLLS DDVINRARFT SEPYYGGDGF 201: TIGKTSGELE AGPGELLNEA ELAAAAEEKE THSFEIDPAL VENVKQRCLP NALNYPMLEE YDFRNDNVNP DLDMELKPHA QPRPYQEKSL SKMFGNGRAR 301: SGIIVLPCGA GKSLVGVSAA ARIKKSCLCL ATNAVSVDQW AYQFKLWSTI KDDQICRFTS DSKERFRGNA GVVVTTYNMI AFGGKRSEEA EKIIEEMRNR 401: EWGLLLMDEV HVVPAHMFRK VISITKSHCK LGLTATLVRE DEKITDLNFL IGPKLYEANW LDLVKGGFIA NVQCAEVWCP MTKEFFAEYL KKENSKKKQA 501: LYVMNPNKFR ACEFLIRFHE QQRGDKIIVF ADNLFALTEY AMKLRKPMIY GATSHIERTK ILEAFKTSKT VNTVFLSKVG DNSIDIPEAN VIIQISSHAG 601: SRRQEAQRLG RILRAKGKLE DRMAGGKEEY NAFFYSLVST DTQEMYYSTK RQQFLIDQGY SFKVITSLPP PDAGSSLGYH SQEEQLSLLG KVLNAGDDMV 701: GLEQLEEDTD GKALKTRRSM GSMSAMSGAN GRVYMEYNSG RQKSGNQSKK PKDPTKRHNI FKKRYV |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)