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AT5G37770.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : EF hand calcium-binding protein family
Curator
Summary (TAIR10)
Encodes a protein with 40% similarity to calmodulin. Binds Ca(2+) and, as a consequence, undergoes conformational changes. CML24 expression occurs in all major organs, and transcript levels are increased from 2- to 15-fold in plants subjected to touch, darkness, heat, cold, hydrogen peroxide, abscisic acid (ABA), and indole-3-acetic acid. However, CML24 protein accumulation changes were not detectable. The putative CML24 regulatory region confers reporter expression at sites of predicted mechanical stress; in regions undergoing growth; in vascular tissues and various floral organs; and in stomata, trichomes, and hydathodes. CML24-underexpressing transgenics are resistant to ABA inhibition of germination and seedling growth, are defective in long-day induction of flowering, and have enhanced tolerance to CoCl(2), molybdic acid, ZnSO(4), and MgCl(2). Also regulates nitric oxide levels.
Computational
Description (TAIR10)
TOUCH 2 (TCH2); FUNCTIONS IN: calcium ion binding; INVOLVED IN: in 13 processes; LOCATED IN: plasma membrane, actin cytoskeleton; EXPRESSED IN: 34 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 (InterPro:IPR018249), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand (InterPro:IPR018248); BEST Arabidopsis thaliana protein match is: calmodulin like 23 (TAIR:AT1G66400.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioGrid:19006eggNOG:COG5126eggNOG:KOG0027EMBL:AB016873
EMBL:AF026473EMBL:AK227202EMBL:AY086500EMBL:BT025709
EMBL:CP002688EnsemblPlants:AT5G37770EnsemblPlants:AT5G37770.1entrez:833755
Gene3D:1.10.238.10GeneID:833755Genevisible:P25070GO:GO:0005509
GO:GO:0005886GO:GO:0009408GO:GO:0009409GO:GO:0009612
GO:GO:0009646GO:GO:0009733GO:GO:0009737GO:GO:0009909
GO:GO:0010038GO:GO:0042542GO:GO:0045087GO:GO:0048574
GO:GO:0051592GO:GO:0080164Gramene:AT5G37770.1hmmpanther:PTHR10891
hmmpanther:PTHR10891:SF573HOGENOM:HOG000233018InParanoid:P25070InterPro:IPR002048
InterPro:IPR011992InterPro:IPR018247iPTMnet:P25070KEGG:ath:AT5G37770
KO:K13448OMA:CLGSMDDPaxDb:P25070PDB:1AVJ
PDBsum:1AVJPfam:P25070Pfam:PF13499Pfscan:PS50222
PhylomeDB:P25070PIR:C34669PRIDE:P25070PRO:PR:P25070
PROSITE:PS00018PROSITE:PS50222ProteinModelPortal:P25070Proteomes:UP000006548
RefSeq:NP_198593.1scanprosite:PS00018SMART:SM00054SMR:P25070
STRING:3702.AT5G37770.1SUPFAM:SSF47473TAIR:AT5G37770tair10-symbols:CML24
tair10-symbols:TCH2UniGene:At.30466UniProt:P25070
Coordinates (TAIR10) chr5:-:14999075..14999560
Molecular Weight (calculated) 17546.90 Da
IEP (calculated) 4.55
GRAVY (calculated) -0.41
Length 161 amino acids
Sequence (TAIR10)
(BLAST)
001: MSSKNGVVRS CLGSMDDIKK VFQRFDKNGD GKISVDELKE VIRALSPTAS PEETVTMMKQ FDLDGNGFID LDEFVALFQI GIGGGGNNRN DVSDLKEAFE
101: LYDLDGNGRI SAKELHSVMK NLGEKCSVQD CKKMISKVDI DGDGCVNFDE FKKMMSNGGG A
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)