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AT5G35620.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:24012629 (2013): nucleus
  • PMID:21166475 (2011): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Eukaryotic initiation factor 4E protein
Curator
Summary (TAIR10)
Cap-binding protein, binds to the 5' cap structure of nuclear-encoded mRNAs. Mutant is resistant to potyvirus infection.
Computational
Description (TAIR10)
LOSS OF SUSCEPTIBILITY TO POTYVIRUS 1 (LSP1); FUNCTIONS IN: RNA binding, RNA 7-methylguanosine cap binding, translation initiation factor activity; INVOLVED IN: translational initiation, response to virus; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Eukaryotic translation initiation factor 4E (eIF-4E) (InterPro:IPR001040), Eukaryotic translation initiation factor 4E (eIF-4E), conserved site (InterPro:IPR019770); BEST Arabidopsis thaliana protein match is: eukaryotic translation initiation factor 4E (TAIR:AT4G18040.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioGrid:18787eggNOG:COG5053eggNOG:KOG1670EMBL:AB013393
EMBL:AF538308EMBL:AY054630EMBL:AY081514EMBL:AY086315
EMBL:BX831945EMBL:CP002688EMBL:U62044EMBL:Y10547
EnsemblPlants:AT5G35620EnsemblPlants:AT5G35620.1entrez:833534Gene3D:3.30.760.10
GeneID:833534Genevisible:O04663GO:GO:0000340GO:GO:0003743
GO:GO:0005634GO:GO:0005737GO:GO:0005829GO:GO:0005845
GO:GO:0006417GO:GO:0009615GO:GO:0050687hmmpanther:PTHR11960
hmmpanther:PTHR11960:SF12HOGENOM:HOG000186751InParanoid:O04663IntAct:O04663
InterPro:IPR001040InterPro:IPR019770InterPro:IPR023398iPTMnet:O04663
KEGG:ath:AT5G35620OMA:HETIFQTPANTHER:PTHR11960PaxDb:O04663
Pfam:O04663Pfam:PF01652PhylomeDB:O04663PRIDE:O04663
PRO:PR:O04663PROSITE:PS00813ProteinModelPortal:O04663Proteomes:UP000006548
RefSeq:NP_198412.1RefSeq:NP_974852.1scanprosite:PS00813SMR:O04663
STRING:3702.AT5G35620.1SUPFAM:SSF55418TAIR:AT5G35620tair10-symbols:EIF(ISO)4E
tair10-symbols:EIF4E2tair10-symbols:eIFiso4Etair10-symbols:LSPtair10-symbols:LSP1
UniGene:At.20245UniProt:O04663
Coordinates (TAIR10) chr5:-:13824946..13826331
Molecular Weight (calculated) 22515.40 Da
IEP (calculated) 5.40
GRAVY (calculated) -0.61
Length 198 amino acids
Sequence (TAIR10)
(BLAST)
001: MATDDVNEPL PAAAELPATE AEKQPHKLER KWSFWFDNQS KKGAAWGASL RKAYTFDTVE DFWGLHETIF QTSKLTANAE IHLFKAGVEP KWEDPECANG
101: GKWTWVVTAN RKEALDKGWL ETLMALIGEQ FDEADEICGV VASVRPQSKQ DKLSLWTRTK SNEAVLMGIG KKWKEILDVT DKITFNNHDD SRRSRFTV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)