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AT5G35520.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 0.998
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : minichromosome instability 12 (mis12)-like
Curator
Summary (TAIR10)
encodes a homologue of the yeast (S. pombe) Mis12 (minichromosome instability) protein. MIS12 co-localizes with 180 bp repeats of centromeric DNA throughout the cell cycle with a similar pattern to AtCENH3/HTR12. Neither of these two proteins completely cover the 180 bp regions based on FISH analysis.
Computational
Description (TAIR10)
MINICHROMOSOME INSTABILITY 12 (MIS12)-LIKE (MIS12); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: mitosis, cell cycle; LOCATED IN: chromosome, centromeric region, nucleus; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Centromere protein Mis12 (InterPro:IPR008685); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410IW39eggNOG:ENOG410YKBMEMBL:AB015477EMBL:AB205161
EMBL:CP002688EnsemblPlants:AT5G35520EnsemblPlants:AT5G35520.1entrez:833516
GeneID:833516GO:GO:0000775GO:GO:0000776GO:GO:0005634
GO:GO:0007067GO:GO:0051301GO:GO:0051321Gramene:AT5G35520.1
hmmpanther:PTHR14527InterPro:IPR008685KEGG:ath:AT5G35520ncoils:Coil
OMA:INEALNCPaxDb:Q2V0Z5Pfam:PF05859ProteinModelPortal:Q2V0Z5
Proteomes:UP000006548RefSeq:NP_198402.2STRING:3702.AT5G35520.1TAIR:AT5G35520
tair10-symbols:ATMIS12tair10-symbols:MIS12UniGene:At.55135UniProt:Q2V0Z5
Coordinates (TAIR10) chr5:+:13701396..13702925
Molecular Weight (calculated) 27127.20 Da
IEP (calculated) 5.14
GRAVY (calculated) -0.54
Length 238 amino acids
Sequence (TAIR10)
(BLAST)
001: MEGSKSEAVF DSMNLNPQIF INEAINSVED YVDQAFDFYA RDASKSLKIK GSDKQKSQAL SNGIARVRGL LLSVIDNRLK LWESYSLRFC FAVPDGFVLP
101: KSEESSSVHQ DGLYDLELDA ELDSLRDKLN VVGKRSVELD SELQALERSS VSRERSLRLV NEALELYDES SMDEIFKEMT KMASELRASV ERLKTRRMKA
201: SESAKVKRLK NHGKEFSAMT FDGKLEDLEK FQAELRKM
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)