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AT1G16970.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : KU70 homolog
Curator
Summary (TAIR10)
Ku80 and ku70 form the heterodimer complex Ku, required for proper maintenance of the telomeric C strand. Ku regulates the extension of the telomeric G strand. Interacts with WEX, and this interaction stimulates the WEX exonuclease activity.
Computational
Description (TAIR10)
KU70 homolog (KU70); FUNCTIONS IN: double-stranded DNA binding, protein binding; INVOLVED IN: DNA repair, response to heat, telomere maintenance; LOCATED IN: nucleus, DNA-dependent protein kinase-DNA ligase 4 complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ku70/Ku80, N-terminal alpha/beta (InterPro:IPR005161), DNA-binding SAP (InterPro:IPR003034), DNA helicase, ATP-dependent, Ku type (InterPro:IPR006164), Spen Paralogue and Orthologue SPOC, C-terminal-like (InterPro:IPR016194), Ku70/Ku80 C-terminal arm (InterPro:IPR005160), DNA helicase, ATP-dependent, Ku70 subunit (InterPro:IPR006165); Has 475 Blast hits to 466 proteins in 181 species: Archae - 0; Bacteria - 6; Metazoa - 182; Fungi - 177; Plants - 52; Viruses - 0; Other Eukaryotes - 58 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-1986-MONOMERBioGrid:23508EC:3.6.4.12eggNOG:ENOG410XNXU
eggNOG:KOG2327EMBL:AC051629EMBL:AF283759EMBL:AK221642
EMBL:CP002684EnsemblPlants:AT1G16970EnsemblPlants:AT1G16970.1entrez:838268
Gene3D:1.10.1600.10Gene3D:1.10.720.30Gene3D:2.40.290.10Gene3D:3.40.50.410
GeneID:838268Genevisible:Q9FQ08GO:GO:0000723GO:GO:0000784
GO:GO:0003684GO:GO:0003690GO:GO:0004003GO:GO:0005524
GO:GO:0005737GO:GO:0006281GO:GO:0006303GO:GO:0006310
GO:GO:0009408GO:GO:0032508GO:GO:0042162GO:GO:0043564
GO:GO:0071480GO:GO:0071481Gramene:AT1G16970.1hmmpanther:PTHR12604
hmmpanther:PTHR12604:SF2HOGENOM:HOG000030793InParanoid:Q9FQ08IntAct:Q9FQ08
InterPro:IPR002035InterPro:IPR003034InterPro:IPR005160InterPro:IPR005161
InterPro:IPR006164InterPro:IPR006165InterPro:IPR016194iPTMnet:Q9FQ08
KEGG:ath:AT1G16970KO:K10884MINT:MINT-1212489OMA:RKAYKFG
PANTHER:PTHR12604:SF2PaxDb:Q9FQ08Pfam:PF02037Pfam:PF02735
Pfam:PF03730Pfam:PF03731Pfam:Q9FQ08Pfscan:PS50800
PhylomeDB:Q9FQ08PIR:D86305PIRSF:PIRSF003033PRIDE:Q9FQ08
PRO:PR:Q9FQ08PROSITE:PS50800ProteinModelPortal:Q9FQ08Proteomes:UP000006548
RefSeq:NP_564012.1SMART:SM00513SMART:SM00559SMR:Q9FQ08
STRING:3702.AT1G16970.1SUPFAM:SSF100939SUPFAM:SSF53300SUPFAM:SSF68906
TAIR:AT1G16970tair10-symbols:ATKU70tair10-symbols:KU70TIGRfam:TIGR00578
TIGRFAMs:TIGR00578UniGene:At.22247UniProt:Q9FQ08
Coordinates (TAIR10) chr1:-:5801159..5805724
Molecular Weight (calculated) 70294.80 Da
IEP (calculated) 4.91
GRAVY (calculated) -0.44
Length 621 amino acids
Sequence (TAIR10)
(BLAST)
001: MELDPDDVFR DEDEDPENDF FQEKEASKEF VVYLIDASPK MFCSTCPSEE EDKQESHFHI AVSCIAQSLK AHIINRSNDE IAICFFNTRE KKNLQDLNGV
101: YVFNVPERDS IDRPTARLIK EFDLIEESFD KEIGSQTGIV SDSRENSLYS ALWVAQALLR KGSLKTADKR MFLFTNEDDP FGSMRISVKE DMTRTTLQRA
201: KDAQDLGISI ELLPLSQPDK QFNITLFYKD LIGLNSDELT EFMPSVGQKL EDMKDQLKKR VLAKRIAKRI TFVICDGLSI ELNGYALLRP AIPGSITWLD
301: STTNLPVKVE RSYICTDTGA IMQDPIQRIQ PYKNQNIMFT VEELSQVKRI STGHLRLLGF KPLSCLKDYH NLKPSTFLYP SDKEVIGSTR AFIALHRSMI
401: QLERFAVAFY GGTTPPRLVA LVAQDEIESD GGQVEPPGIN MIYLPYANDI RDIDELHSKP GVAAPRASDD QLKKASALMR RLELKDFSVC QFANPALQRH
501: YAILQAIALD ENELRETRDE TLPDEEGMNR PAVVKAIEQF KQSIYGDDPD EESDSGAKEK SKKRKAGDAD DGKYDYIELA KTGKLKDLTV VELKTYLTAN
601: NLLVSGKKEV LINRILTHIG K
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)