suba logo
AT5G27450.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

.
SUBAcon:
cytosol 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:21166475 (2011): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : mevalonate kinase
Curator
Summary (TAIR10)
Encodes a protein with mevalonate kinase activity involved in the mevalonate pathway.
Computational
Description (TAIR10)
mevalonate kinase (MK); FUNCTIONS IN: mevalonate kinase activity; INVOLVED IN: isoprenoid biosynthetic process, metabolic process, phosphorylation; LOCATED IN: cytoplasm; EXPRESSED IN: 30 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Mevalonate kinase (InterPro:IPR006205), GHMP kinase, ATP-binding, conserved site (InterPro:IPR006203), Mevalonate/galactokinase (InterPro:IPR006206), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), GHMP kinase (InterPro:IPR006204), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721), GHMP kinase, C-terminal (InterPro:IPR013750); Has 2155 Blast hits to 2126 proteins in 899 species: Archae - 214; Bacteria - 1320; Metazoa - 166; Fungi - 147; Plants - 62; Viruses - 0; Other Eukaryotes - 246 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-657-MONOMERBioCyc:ARA:GQT-658-MONOMERBioCyc:MetaCyc:AT5G27450-MONOMEREC:2.7.1.36
eggNOG:COG1577eggNOG:KOG1511EMBL:AC007123EMBL:AF141853
EMBL:AY084333EMBL:AY093165EMBL:BT002104EMBL:CP002688
EMBL:L77688EMBL:X77793EnsemblPlants:AT5G27450EnsemblPlants:AT5G27450.1
EnsemblPlants:AT5G27450.2EnsemblPlants:AT5G27450.3entrez:832804Gene3D:3.30.230.10
Gene3D:3.30.70.890GeneID:832804Genevisible:P46086GO:GO:0004496
GO:GO:0005524GO:GO:0005829GO:GO:0016126GO:GO:0019287
Gramene:AT5G27450.1Gramene:AT5G27450.2Gramene:AT5G27450.3gramene_pathway:2.7.1.36
gramene_pathway:PWY-922gramene_plant_reactome:1119615gramene_plant_reactome:6873704hmmpanther:PTHR10457
hmmpanther:PTHR10457:SF4HOGENOM:HOG000188934InParanoid:P46086InterPro:IPR006203
InterPro:IPR006204InterPro:IPR006205InterPro:IPR006206InterPro:IPR013750
InterPro:IPR014721InterPro:IPR020568iPTMnet:P46086KEGG:00052+2.7.1.6
KEGG:00520+2.7.1.6KEGG:00900+2.7.1.36KEGG:ath:AT5G27450KO:K00869
OMA:SRLTKFPPANTHER:PTHR10457PANTHER:PTHR10457:SF4PaxDb:P46086
Pfam:P46086Pfam:PF00288Pfam:PF08544PhylomeDB:P46086
PIR:S42088PRIDE:P46086PRINTS:PR00959PRO:PR:P46086
PROSITE:PS00627ProteinModelPortal:P46086Proteomes:UP000006548Reactome:R-ATH-191273
RefSeq:NP_001190411.1RefSeq:NP_198097.1RefSeq:NP_851084.1scanprosite:PS00627
SMR:P46086STRING:3702.AT5G27450.1SUPFAM:SSF54211SUPFAM:SSF55060
TAIR:AT5G27450tair10-symbols:MKtair10-symbols:MVKTIGRfam:TIGR00549
TIGRFAMs:TIGR00549UniGene:At.30805UniGene:At.5392UniPathway:UPA00057
unipathway:UPA00214UniProt:P46086
Coordinates (TAIR10) chr5:+:9691051..9692975
Molecular Weight (calculated) 40646.10 Da
IEP (calculated) 6.78
GRAVY (calculated) 0.08
Length 378 amino acids
Sequence (TAIR10)
(BLAST)
001: MEVKARAPGK IILAGEHAVV HGSTAVAAAI DLYTYVTLRF PLPSAENNDR LTLQLKDISL EFSWSLARIK EAIPYDSSTL CRSTPASCSE ETLKSIAVLV
101: EEQNLPKEKM WLSSGISTFL WLYTRIIGFN PATVVINSEL PYGSGLGSSA ALCVALTAAL LASSISEKTR GNGWSSLDET NLELLNKWAF EGEKIIHGKP
201: SGIDNTVSAY GNMIKFCSGE ITRLQSNMPL RMLITNTRVG RNTKALVSGV SQRAVRHPDA MKSVFNAVDS ISKELAAIIQ SKDETSVTEK EERIKELMEM
301: NQGLLLSMGV SHSSIEAVIL TTVKHKLVSK LTGAGGGGCV LTLLPTGTVV DKVVEELESS GFQCFTALIG GNGAQICY
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)