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AT5G23450.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : long-chain base (LCB) kinase 1
Curator
Summary (TAIR10)
Encodes a sphingosine kinase that specifically phosphorylates D-erythro-dihydrosphingosine (DHS), but not N-acetyl-DHS or D-threo-DHS. It also also phosphorylates D-erythro-sphingosine, trans-4, trans-8-sphingadienine and phytosphingosine.
Computational
Description (TAIR10)
long-chain base (LCB) kinase 1 (LCBK1); FUNCTIONS IN: diacylglycerol kinase activity, D-erythro-sphingosine kinase activity; INVOLVED IN: activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway, sphingolipid biosynthetic process; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Diacylglycerol kinase, catalytic domain (InterPro:IPR001206); BEST Arabidopsis thaliana protein match is: sphingosine kinase 1 (TAIR:AT4G21540.1); Has 4352 Blast hits to 4113 proteins in 1166 species: Archae - 8; Bacteria - 2944; Metazoa - 550; Fungi - 174; Plants - 282; Viruses - 0; Other Eukaryotes - 394 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G23450-MONOMERBioCyc:ARA:GQT-500-MONOMERBioCyc:ARA:GQT-501-MONOMERBioGrid:17686
EC:2.7.-.-eggNOG:COG1597eggNOG:KOG1116EMBL:AB018110
EMBL:AB046717EMBL:AK317480EMBL:AY139759EMBL:BT004544
EMBL:CP002688EnsemblPlants:AT5G23450EnsemblPlants:AT5G23450.1EnsemblPlants:AT5G23450.2
entrez:832411ExpressionAtlas:Q9LRB0GeneID:832411Genevisible:Q9LRB0
GO:GO:0005524GO:GO:0017050GO:GO:0030148hmmpanther:PTHR12358
hmmpanther:PTHR12358:SF33HOGENOM:HOG000243538InParanoid:Q9LRB0InterPro:IPR001206
InterPro:IPR016064iPTMnet:Q9LRB0PaxDb:Q9LRB0Pfam:PF00781
Pfam:Q9LRB0Pfscan:PS50146PhylomeDB:Q9LRB0PRIDE:Q9LRB0
PRO:PR:Q9LRB0PROSITE:PS50146ProteinModelPortal:Q9LRB0Proteomes:UP000006548
RefSeq:NP_568432.1RefSeq:NP_851065.1SMART:SM00046SMR:Q9LRB0
STRING:3702.AT5G23450.3SUPFAM:SSF111331SwissPalm:Q9LRB0TAIR:AT5G23450
tair10-symbols:ATLCBK1tair10-symbols:LCBK1UniGene:At.22459UniProt:Q9LRB0
Coordinates (TAIR10) chr5:-:7905041..7908960
Molecular Weight (calculated) 83596.30 Da
IEP (calculated) 8.47
GRAVY (calculated) -0.29
Length 763 amino acids
Sequence (TAIR10)
(BLAST)
001: MQKSGVNRNP SLKVAIPQAQ QSLRRLGFCS QIATGGSQQS SPIVFPEKRN KKVKASSRRG EVTNDPQVKP KPDEHRIDIG GGDEKSDLLG SLVYAGKLVL
101: DKRKSASGKD ATEIQQPAAT DISIKKAVDA KLTSSALVWG SDMLQLNDVV SVTYNVGLRH FTVHAYPIGK GSCGLSCFTK PKRSRKDFRF VAPTVEEAVQ
201: WVASFGDQQC FINCLPHPLV AKKQASSELF SVPIDTPPEL VFRCKSAPKM LVILNPRSGH GRSIKVFHNV VEPIFKLAGI KMEVVKTTKA GHARELASTV
301: DINLCSDGII CVGGDGIINE VLNGLLTRSN PKEGVSIPIG IVPAGSDNSL VWTVLGVRDP ISAALSIVKG GLTATDVFAV EWIHTGIIHF GMTVSYYGFV
401: SDVLELSEKY QKRFGPLRYF VAGFLKFMCL PKYSYEVEYL PAQKEDAEGK IRLEKEAVDM QDLYTDVMRR SSREGFPRAS SLSSIDSIMT PSVGELDTCS
501: STHASTEPSE YVRGIDPKMK RLSSGRRDVT AEPEVIHPQA QSTTPNWPRT RSKSRMDKGW MGLTSVQDPP TRCSWGNTGG QDREDISSTV SDPGPIWDAG
601: PKWDTEPSAW DVENSIELPG PPEDIETGLR KQSITPIFED KWVSRKGHFL GIMVCNHACR TVQSSQVVAP NSEHDDGTMD MLLVHGCGRL RLLRFFILLQ
701: TGRHLSLPYV ECVKVKSVKI KAGKNTHDSC GIDGELFALH GEVISTMLPE QCRLIGNAPG RHS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)