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AT4G25720.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
endoplasmic reticulum 0.886
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:22923678 (2012): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : glutaminyl cyclase
Curator
Summary (TAIR10)
This locus encodes a protein with similarity to gamma-glutamylcyclotransferase that may be involved in catalyzing the formation of pyroglutate residue on proteins that have been post-translationally processed to reveal a glutamine at their N-terminus. Enzymatic assays to test the function of this protein were performed using a truncated form of the protein lacking a signal peptide that is most similar to the AT4G25720.1 protein model.
Computational
Description (TAIR10)
glutaminyl cyclase (QC); FUNCTIONS IN: glutaminyl-peptide cyclotransferase activity, catalytic activity; INVOLVED IN: peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glutamine cyclotransferase (InterPro:IPR007788), Nitrous oxide reductase, N-terminal (InterPro:IPR011045); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G25720-MONOMERBioCyc:ARA:GQT-2029-MONOMERBioCyc:ARA:GQT-2030-MONOMEREC:2.3.2.5
eggNOG:COG3823eggNOG:ENOG410IV7QEMBL:AK316976EMBL:AL050400
EMBL:AL161563EMBL:AY084653EMBL:BT001929EMBL:CP002687
EnsemblPlants:AT4G25720EnsemblPlants:AT4G25720.1entrez:828677ExpressionAtlas:Q84WV9
Gene3D:2.130.10.10GeneID:828677Genevisible:Q84WV9GO:GO:0005789
GO:GO:0005886GO:GO:0016021GO:GO:0016603GO:GO:0017186
hmmpanther:PTHR31270hmmpanther:PTHR31270:SF0HOGENOM:HOG000017142InParanoid:Q84WV9
InterPro:IPR007788InterPro:IPR011044InterPro:IPR015943KEGG:ath:AT4G25720
OMA:CPKASFYPaxDb:Q84WV9Pfam:PF05096Pfam:Q84WV9
PhylomeDB:Q84WV9PIR:T09564PRIDE:Q84WV9PRO:PR:Q84WV9
ProteinModelPortal:Q84WV9Proteomes:UP000006548RefSeq:NP_001031716.1RefSeq:NP_001031717.1
RefSeq:NP_567727.1SMR:Q84WV9STRING:3702.AT4G25720.1SUPFAM:SSF50969
TAIR:AT4G25720tair10-symbols:ATQCtair10-symbols:QCtair10-symbols:QCT
TMHMM:TMhelixUniGene:At.28493UniProt:Q84WV9
Coordinates (TAIR10) chr4:-:13099929..13102470
Molecular Weight (calculated) 36270.70 Da
IEP (calculated) 10.21
GRAVY (calculated) -0.33
Length 320 amino acids
Sequence (TAIR10)
(BLAST)
001: MATRSPYKRQ TKRSMIQSLP ASSSASSRRR FISRKRFAMM IPLALLSGAV FLFFMPFNSW GQSSGSSLDL SHRINEIEVV AEFPHDPDAF TQGLLYAGND
101: TLFESTGLYG KSSVRKVDLR TGKVEILEKM DNTYFGEGLT LLGERLFQVA WLTNTGFTYD LRNLSKVKPF KHHMKDGWGL ATDGKALFGS DGTSTLYRMD
201: PQTMKVTDKH IVRYNGREVR YLNELEYINN EVWANVWQSD CIARISPKDG SLLGWILLSK LSRGLLKSGH RGIDVLNGIA WDSDKQRLFV TGKLWPKLYQ
301: IKLKQASAKS GNYIEQQCLV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)