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AT4G21980.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Ubiquitin-like superfamily protein
Curator
Summary (TAIR10)
Encodes APG8, a component of autophagy conjugation pathway. Delivered to the lumens of vacuole under nitrogen-starvation condition. Highest expression in flowers. mRNA abundance increased during dark-induced carbon starvation. Predominantly cytoplasmic with or without N starvation. Upon concanamycin A the protein accumulates in the central vacuole as punctuate structures that resemble autophagic bodies. This localization is more abundant upon N starvation.
Computational
Description (TAIR10)
AUTOPHAGY 8A (APG8A); CONTAINS InterPro DOMAIN/s: Light chain 3 (LC3) (InterPro:IPR004241); BEST Arabidopsis thaliana protein match is: Ubiquitin-like superfamily protein (TAIR:AT4G04620.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioGrid:13576eggNOG:ENOG4111JATeggNOG:KOG1654EMBL:AB073175
EMBL:AF492759EMBL:AL022140EMBL:AL161556EMBL:AY085349
EMBL:BT002024EMBL:BT006522EMBL:CP002687EnsemblPlants:AT4G21980
EnsemblPlants:AT4G21980.1entrez:828287ExpressionAtlas:Q8LEM4GeneID:828287
Genevisible:Q8LEM4GO:GO:0000421GO:GO:0005874GO:GO:0006914
GO:GO:0015031GO:GO:0033110hmmpanther:PTHR10969hmmpanther:PTHR10969:SF43
HOGENOM:HOG000232034InParanoid:Q8LEM4InterPro:IPR004241InterPro:IPR029071
PANTHER:PTHR10969PaxDb:Q8LEM4Pfam:PF02991Pfam:Q8LEM4
PhylomeDB:Q8LEM4PIR:T49105PRO:PR:Q8LEM4ProteinModelPortal:Q8LEM4
Proteomes:UP000006548RefSeq:NP_567642.1SMR:Q8LEM4STRING:3702.AT4G21980.2
SUPFAM:SSF54236TAIR:AT4G21980tair10-symbols:APG8Atair10-symbols:ATG8A
UniGene:At.2106UniGene:At.24034UniProt:Q8LEM4
Coordinates (TAIR10) chr4:+:11655913..11656809
Molecular Weight (calculated) 13695.60 Da
IEP (calculated) 9.29
GRAVY (calculated) -0.24
Length 122 amino acids
Sequence (TAIR10)
(BLAST)
001: MAKSSFKISN PLEARMSESS RIREKYPDRI PVIVEKAGQS DVPDIDKKKY LVPADLTVGQ FVYVVRKRIK LGAEKAIFVF VKNTLPPTAA LMSAIYEEHK
101: DEDGFLYMTY SGENTFGSLT VA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)