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AT3G47340.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 0.999
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:30961429 (2019): nucleus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : glutamine-dependent asparagine synthase 1
Curator
Summary (TAIR10)
encodes a glutamine-dependent asparagine synthetase, the predicted ASN1 peptide contains a purF-type glutamine-binding domain, and is expressed predominantly in shoot tissues, where light has a negative effect on its mRNA accumulation. Expression is induced within 3 hours of dark treatment, in senescing leaves and treatment with exogenous photosynthesis inhibitor. Induction of gene expression was suppressed in excised leaves supplied with sugar. The authors suggest that the gene's expression pattern is responding to the level of sugar in the cell.
Computational
Description (TAIR10)
glutamine-dependent asparagine synthase 1 (ASN1); CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Asparagine synthase (InterPro:IPR001962), Asparagine synthase, glutamine-hydrolyzing (InterPro:IPR006426), Glutamine amidotransferase, type II (InterPro:IPR017932); BEST Arabidopsis thaliana protein match is: asparagine synthetase 2 (TAIR:AT5G65010.1); Has 10466 Blast hits to 10069 proteins in 1927 species: Archae - 313; Bacteria - 6097; Metazoa - 215; Fungi - 282; Plants - 342; Viruses - 7; Other Eukaryotes - 3210 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-1413-MONOMERBioCyc:ARA:GQT-2583-MONOMEREC:6.3.5.4eggNOG:COG0367
eggNOG:KOG0571EMBL:AF419557EMBL:AL096860EMBL:AY072214
EMBL:AY096592EMBL:CP002686EMBL:L29083EnsemblPlants:AT3G47340
EnsemblPlants:AT3G47340.1entrez:823888ExpressionAtlas:P49078Gene3D:3.40.50.620
Gene3D:3.60.20.10GeneID:823888Genevisible:P49078GO:GO:0004066
GO:GO:0005524GO:GO:0005829GO:GO:0006529GO:GO:0006541
GO:GO:0009063GO:GO:0009646GO:GO:0009744GO:GO:0009749
GO:GO:0009750GO:GO:0042803GO:GO:0043617GO:GO:0070981
gramene_pathway:6.3.5.4gramene_pathway:ASPARAGINE-BIOSYNTHESIShmmpanther:PTHR11772hmmpanther:PTHR11772:SF13
HOGENOM:HOG000027493InParanoid:P49078InterPro:IPR001962InterPro:IPR006426
InterPro:IPR014729InterPro:IPR017932InterPro:IPR029055KEGG:00250+6.3.5.4
KEGG:ath:AT3G47340KO:K01953merops:C44.974OMA:HKAPNYK
PaxDb:P49078Pfam:P49078Pfam:PF00733Pfam:PF13537
Pfscan:PS51278PhylomeDB:P49078PIR:T12989PRIDE:P49078
PRO:PR:P49078PROSITE:PS51278ProteinModelPortal:P49078Proteomes:UP000006548
Reactome:R-ATH-70614RefSeq:NP_190318.1SMR:P49078STRING:3702.AT3G47340.1
SUPFAM:SSF52402SUPFAM:SSF56235TAIR:AT3G47340tair10-symbols:ASN1
tair10-symbols:AT-ASN1tair10-symbols:DIN6TIGRfam:TIGR01536TIGRFAMs:TIGR01536
UniGene:At.20782UniPathway:UPA00134UniProt:P49078
Coordinates (TAIR10) chr3:-:17438136..17441043
Molecular Weight (calculated) 65624.10 Da
IEP (calculated) 6.63
GRAVY (calculated) -0.33
Length 584 amino acids
Sequence (TAIR10)
(BLAST)
001: MCGILAVLGC SDDSQAKRVR VLELSRRLRH RGPDWSGLYQ NGDNYLAHQR LAVIDPASGD QPLFNEDKTI VVTVNGEIYN HEELRKRLKN HKFRTGSDCE
101: VIAHLYEEYG VDFVDMLDGI FSFVLLDTRD NSFMVARDAI GVTSLYIGWG LDGSVWISSE MKGLNDDCEH FETFPPGHFY SSKLGGFKQW YNPPWFNESV
201: PSTPYEPLAI RRAFENAVIK RLMTDVPFGV LLSGGLDSSL VASITARHLA GTKAAKQWGP QLHSFCVGLE GSPDLKAGKE VAEYLGTVHH EFHFSVQDGI
301: DAIEDVIYHV ETYDVTTIRA STPMFLMSRK IKSLGVKMVL SGEGADEIFG GYLYFHKAPN KKEFHQETCR KIKALHKYDC LRANKSTSAF GLEARVPFLD
401: KDFINTAMSL DPESKMIKPE EGRIEKWVLR RAFDDEERPY LPKHILYRQK EQFSDGVGYS WIDGLKDHAA QNVNDKMMSN AGHIFPHNTP NTKEAYYYRM
501: IFERFFPQNS ARLTVPGGAT VACSTAKAVE WDASWSNNMD PSGRAAIGVH LSAYDGKNVA LTIPPLKAID NMPMMMGQGV VIQS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)