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AT3G18730.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : tetratricopeptide repeat (TPR)-containing protein
Curator
Summary (TAIR10)
Encodes a protein with an important role in cell division control and plant morphogenesis and may also play a role in genome maintenance. May be involved in mitosis through interaction with TSA1. In cells synchronized for cell division, TSA1 and TSK relocalize to ends of spindle microtubules that are ahead of separating chromatids during metaphase and anaphase of mitosis.
Computational
Description (TAIR10)
TONSOKU (TSK); FUNCTIONS IN: protein binding; INVOLVED IN: G2/M transition of mitotic cell cycle, meristem structural organization, regulation of meristem structural organization, cell division; LOCATED IN: nucleus, membrane; EXPRESSED IN: leaf; CONTAINS InterPro DOMAIN/s: Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide repeat (InterPro:IPR019734); Has 6425 Blast hits to 3886 proteins in 382 species: Archae - 66; Bacteria - 1534; Metazoa - 3543; Fungi - 23; Plants - 266; Viruses - 0; Other Eukaryotes - 993 (source: NCBI BLink).
Protein Annotations
BioGrid:6737eggNOG:COG0457eggNOG:KOG0619eggNOG:KOG1124
EMBL:AB026654EMBL:AB112744EMBL:AJ579629EMBL:AY560347
EMBL:BN000267EMBL:CP002686EnsemblPlants:AT3G18730EnsemblPlants:AT3G18730.1
entrez:821404Gene3D:1.25.40.10Gene3D:3.80.10.10GeneID:821404
GO:GO:0000086GO:GO:0005634GO:GO:0005654GO:GO:0009933
GO:GO:0009934GO:GO:0016020GO:GO:0016568GO:GO:0051301
Gramene:AT3G18730.1hmmpanther:PTHR10098hmmpanther:PTHR10098:SF111HOGENOM:HOG000083351
InParanoid:Q6Q4D0InterPro:IPR001611InterPro:IPR011990InterPro:IPR019734
InterPro:IPR032675iPTMnet:Q6Q4D0KEGG:ath:AT3G18730MINT:MINT-8065038
ncoils:CoilOMA:CLYYLQLPaxDb:Q6Q4D0Pfam:PF13181
Pfam:PF13516Pfam:Q6Q4D0PhylomeDB:Q6Q4D0PRIDE:Q6Q4D0
PRO:PR:Q6Q4D0ProteinModelPortal:Q6Q4D0Proteomes:UP000006548RefSeq:NP_188503.2
SMART:SM00028SMR:Q6Q4D0STRING:3702.AT3G18730.1SUPFAM:SSF48452
SUPFAM:SSF52047TAIR:AT3G18730tair10-symbols:BRU1tair10-symbols:MGO3
tair10-symbols:TSKUniGene:At.38502UniProt:Q6Q4D0
Coordinates (TAIR10) chr3:-:6446062..6453045
Molecular Weight (calculated) 146490.00 Da
IEP (calculated) 5.38
GRAVY (calculated) -0.42
Length 1311 amino acids
Sequence (TAIR10)
(BLAST)
0001: MGRLDVAAAK RAYRKAEEVG DRREQARWAN NVGDILKNHG EYVDALKWFR IDYDISVKYL PGKDLLPTCQ SLGEIYLRLE NFEEALIYQK KHLQLAEEAN
0101: DTVEKQRACT QLGRTYHEMF LKSEDDCEAI QSAKKYFKKA MELAQILKEK PPPGESSGFL EEYINAHNNI GMLDLDLDNP EAARTILKKG LQICDEEEVR
0201: EYDAARSRLH HNLGNVFMAL RSWDEAKKHI EMDINICHKI NHVQGEAKGY INLAELHNKT QKYIDALLCY GKASSLAKSM QDESALVEQI EHNTKIVKKS
0301: MKVMEELREE ELMLKKLSAE MTDAKGTSEE RKSMLQVNAC LGSLIDKSSM VFAWLKHLQY SKRKKKISDE LCDKEKLSDA FMIVGESYQN LRNFRKSLKW
0401: FIRSYEGHEA IGNLEGQALA KINIGNGLDC IGEWTGALQA YEEGYRIALK ANLPSIQLSA LEDIHYIHMM RFGNAQKASE LKETIQNLKE SEHAEKAECS
0501: TQDECSETDS EGHANVSNDR PNACSSPQTP NSLRSERLAD LDEANDDVPL ISFLQPGKRL FKRKQVSGKQ DADTDQTKKD FSVVADSQQT VAGRKRIRVI
0601: LSDDESETEY ELGCPKDSSH KVLRQNEEVS EESMYFDGAI NYTDNRAIQD NVEEGSCSYT PLHPIKVAPN VSNCRSLSNN IAVETTGRRK KGSQCDVGDS
0701: NGTSCKTGAA LVNFHAYSKT EDRKIKIEIE NEHIALDSCS HDDESVKVEL TCLYYLQLPD DEKSKGLLPI IHHLEYGGRV LKPLELYAIL RDSSENVVIE
0801: ASVDGWVHKR LMKLYMDCCQ SLSEKPSMKL LKKLYISEVE DDINVSECEL QDISAAPLLC ALHVHNIAML DLSHNMLGNG TMEKLKQLFA SSSQMYGALT
0901: LDLHCNRFGP TALFQICECP VLFTRLEVLN VSRNRLTDAC GSYLSTIVKN CRALYSLNVE HCSLTSRTIQ KVANALDSKS GLSQLCIGYN NPVSGSSIQN
1001: LLAKLATLSS FAELSMNGIK LSSQVVDSLY ALVKTPSLSK LLVGSSGIGT DGAIKVTESL CYQKEETVKL DLSCCGLASS FFIKLNQDVT LTSSILEFNV
1101: GGNPITEEGI SALGELLRNP CSNIKVLILS KCHLKLAGLL CIIQALSDNK NLEELNLSDN AKIEDETVFG QPVKERSVMV EQEHGTCKSV TSMDKEQELC
1201: ETNMECDDLE VADSEDEQIE EGTATSSSLS LPRKNHIVKE LSTALSMANQ LKILDLSNNG FSVEALETLY MSWSSSSSRT GIAQRHVKEE TVHFYVEGKM
1301: CCGVKSCCRK D
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)