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AT3G08720.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : serine/threonine protein kinase 2
Curator
Summary (TAIR10)
Encodes a ribosomal-protein S6 kinase. Gene expression is induced by cold and salt (NaCl). Activation of AtS6k is regulated by 1-naphthylacetic acid and kinetin, at least in part, via a lipid kinase-dependent pathway. Phosphorylates specifically mammalian and plant S6 at 25 degrees C but not at 37 degrees C. Involved in translational up-regulation of ribosomal proteins.
Computational
Description (TAIR10)
serine/threonine protein kinase 2 (S6K2); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), AGC-kinase, C-terminal (InterPro:IPR000961), Protein kinase, C-terminal (InterPro:IPR017892), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: protein-serine kinase 1 (TAIR:AT3G08730.1); Has 133901 Blast hits to 131707 proteins in 4554 species: Archae - 204; Bacteria - 15943; Metazoa - 48718; Fungi - 13429; Plants - 32816; Viruses - 561; Other Eukaryotes - 22230 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410XNPHeggNOG:KOG0598EMBL:AK316712EMBL:BT026369
EnsemblPlants:AT3G08720EnsemblPlants:AT3G08720.1EnsemblPlants:AT3G08720.2entrez:820019
ExpressionAtlas:Q0V851GeneID:820019GO:GO:0004674GO:GO:0005524
Gramene:AT3G08720.1Gramene:AT3G08720.2hmmpanther:PTHR24351hmmpanther:PTHR24351:SF80
HOGENOM:HOG000233033InterPro:IPR000719InterPro:IPR000961InterPro:IPR008271
InterPro:IPR011009InterPro:IPR017441InterPro:IPR017892KEGG:ath:AT3G08720
KO:K04688OMA:THCIANFPfam:PF00069Pfam:PF00433
Pfam:Q39030Pfscan:PS50011Pfscan:PS51285PhylomeDB:Q0V851
PROSITE:PS00107PROSITE:PS00108PROSITE:PS50011PROSITE:PS51285
RefSeq:NP_187484.1RefSeq:NP_850543.1scanprosite:PS00107scanprosite:PS00108
SMART:SM00133SMART:SM00220SMR:Q0V851STRING:3702.AT3G08720.1
SUPFAM:SSF56112TAIR:AT3G08720tair10-symbols:ATPK19tair10-symbols:ATPK2
tair10-symbols:ATS6K2tair10-symbols:S6K2UniGene:At.266UniProt:Q0V851
UniProt:Q39030
Coordinates (TAIR10) chr3:-:2648625..2650407
Molecular Weight (calculated) 53040.30 Da
IEP (calculated) 6.72
GRAVY (calculated) -0.46
Length 471 amino acids
Sequence (TAIR10)
(BLAST)
001: MVSSQCSVAN KNQTGKPFQK HLSLSISPPK SVLGDNLELQ FSDVFGPMPE ANSEEACDVA YDEPAVVYSR SHSLVGPSLV VSHSLKMNKL TLRETEDSVD
101: LVECVEGESI KENDEFSGND DTDSEKSPEE VSGVVGIEDF EVLKVVGQGA FGKVYQVRKK DTSEIYAMKV MRKDKIVEKN HAEYMKAERD ILTKIDHPFI
201: VQLKYSFQTK YRLYLVLDFI NGGHLFFQLY HQGLFREDLA RVYTAEIVSA VSHLHEKGIM HRDLKPENIL MDVDGHVMLT DFGLAKEFEE NTRSNSMCGT
301: TEYMAPEIVR GKGHDKAADW WSVGILLYEM LTGKPPFLGS KGKIQQKIVK DKIKLPQFLS NEAHALLKGL LQKEPERRLG SGPSGAEEIK KHKWFKAINW
401: KKLEAREVQP SFKPAVSGRQ CIANFDKCWT DMSVLDSPAS SPNSDAKANP FTNFTYVRPP HSFLHRTTSN L
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)