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AT3G07370.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 0.923
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : carboxyl terminus of HSC70-interacting protein
Curator
Summary (TAIR10)
Encodes AtCHIP, a new class of E3 ubiquitin ligases with three tetratricopeptide repeats and a U-box domain, structurally similar to the animal CHIP proteins. Plays an important role in plant cellular metabolism under temperature stress conditions. Functions as an E3 ubiquitin ligase of protein phosphatase 2A subunits and alters plant response to abscisic acid treatment.
Computational
Description (TAIR10)
carboxyl terminus of HSC70-interacting protein (CHIP); FUNCTIONS IN: ubiquitin-protein ligase activity; INVOLVED IN: response to salt stress, response to temperature stimulus, response to abscisic acid stimulus, protein ubiquitination; LOCATED IN: ubiquitin ligase complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), U box domain (InterPro:IPR003613), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: protein phosphatase 5.2 (TAIR:AT2G42810.2); Has 6721 Blast hits to 5903 proteins in 442 species: Archae - 38; Bacteria - 482; Metazoa - 2236; Fungi - 1004; Plants - 1936; Viruses - 0; Other Eukaryotes - 1025 (source: NCBI BLink).
Protein Annotations
BioGrid:5260EC:6.3.2.-eggNOG:ENOG410ZC2ReggNOG:KOG4642
EMBL:AC009853EMBL:AY042807EMBL:AY064647EMBL:CP002686
EnsemblPlants:AT3G07370EnsemblPlants:AT3G07370.1entrez:819925Gene3D:1.25.40.10
Gene3D:3.30.40.10GeneID:819925Genevisible:Q9SRS9GO:GO:0004842
GO:GO:0009266GO:GO:0009651GO:GO:0009737GO:GO:0016567
GO:GO:0016874GO:GO:0051087Gramene:AT3G07370.1hmmpanther:PTHR22904
hmmpanther:PTHR22904:SF363HOGENOM:HOG000163725InParanoid:Q9SRS9InterPro:IPR003613
InterPro:IPR011990InterPro:IPR013026InterPro:IPR013083InterPro:IPR019734
KEGG:ath:AT3G07370KO:K09561ncoils:CoilOMA:NCFKKER
PaxDb:Q9SRS9Pfam:PF04564Pfam:PF07719Pfam:PF13181
Pfam:PF13414Pfam:Q9SRS9Pfscan:PS50293Pfscan:PS51698
PhylomeDB:Q9SRS9PRIDE:Q9SRS9PRO:PR:Q9SRS9PROSITE:PS50293
PROSITE:PS51698ProteinModelPortal:Q9SRS9Proteomes:UP000006548RefSeq:NP_566305.1
SMART:SM00028SMART:SM00504SMR:Q9SRS9STRING:3702.AT3G07370.1
SUPFAM:SSF48452SUPFAM:SSF57850TAIR:AT3G07370tair10-symbols:ATCHIP
tair10-symbols:CHIPUniGene:At.18421UniPathway:UPA00143UniProt:Q9SRS9
Coordinates (TAIR10) chr3:-:2358323..2360301
Molecular Weight (calculated) 31657.00 Da
IEP (calculated) 6.52
GRAVY (calculated) -0.44
Length 278 amino acids
Sequence (TAIR10)
(BLAST)
001: MVTGVASAMA ERLKEDGNNC FKKERFGAAI DAYTEAIALS PNVPAYWTNR ALCHMKRKDW TKVEEDCRKA IQLVHNSVKA HYMLGLALLQ KKEFTNGVKE
101: LQRALDLGRC SNPTGYMVEE IWEELSKAKY MEWELVSAMR SWELNSLKET CEAALNQQRA LDMSRTEESS DEAYTAHTER LKALERVFKK AAEEDKPTEV
201: PDYLCCNITL EIFRDPVISP SGVTYERAAI LEHLKKVGKF DPITREKIDP ANLVPNLAIK EAVAAYLEKH VWAYKMGC
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)