suba logo
AT2G01980.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

.
SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : sodium proton exchanger, putative (NHX7) (SOS1)
Curator
Summary (TAIR10)
Encodes a plasma membrane-localized Na+/H+ antiporter SOS1. Functions in the extrusion of toxic Na+ from cells and is essential for plant salt tolerance. Has 12 predicted transmembrane domains in the N-terminal region and a long cytoplasmic tail of approx. 700 aa at the C-terminal side. SOS1 interacts through its predicted cytoplasmic tail with RCD1, a regulator of oxidative-stress responses, suggesting that SOS1 might function in oxidative-stress tolerance.
Computational
Description (TAIR10)
SALT OVERLY SENSITIVE 1 (SOS1); FUNCTIONS IN: sodium:hydrogen antiporter activity; INVOLVED IN: in 7 processes; LOCATED IN: plasma membrane, chloroplast envelope; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cyclic nucleotide-binding (InterPro:IPR000595), Cation/H+ exchanger, conserved region (InterPro:IPR018422), Cation/H+ exchanger (InterPro:IPR006153), Cyclic nucleotide-binding-like (InterPro:IPR018490), RmlC-like jelly roll fold (InterPro:IPR014710), Na+/H+ exchanger, isoforms 7/8, conserved region (InterPro:IPR018418); BEST Arabidopsis thaliana protein match is: Na+/H+ exchanger 8 (TAIR:AT1G14660.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioGrid:132DIP:DIP-52883NeggNOG:COG0025eggNOG:KOG1965
EMBL:AC006532EMBL:AF256224EMBL:AY062746EMBL:CP002685
EnsemblPlants:AT2G01980EnsemblPlants:AT2G01980.1entrez:814729ExpressionAtlas:Q9LKW9
GeneID:814729Genevisible:Q9LKW9GO:GO:0000302GO:GO:0005886
GO:GO:0006814GO:GO:0006979GO:GO:0009651GO:GO:0009941
GO:GO:0010163GO:GO:0015299GO:GO:0016021GO:GO:0042542
GO:GO:2000377Gramene:AT2G01980.1hmmpanther:PTHR10110hmmpanther:PTHR10110:SF86
HOGENOM:HOG000029489InParanoid:Q9LKW9IntAct:Q9LKW9InterPro:IPR006153
InterPro:IPR018422InterPro:IPR018490iPTMnet:Q9LKW9KEGG:ath:AT2G01980
OMA:TYFAVERPANTHER:PTHR10110PaxDb:Q9LKW9Pfam:PF00999
Pfam:Q9LKW9PhylomeDB:Q9LKW9PIR:E84431PRIDE:Q9LKW9
PRO:PR:Q9LKW9ProteinModelPortal:Q9LKW9Proteomes:UP000006548RefSeq:NP_178307.2
STRING:3702.AT2G01980.1SUPFAM:SSF51206TAIR:AT2G01980tair10-symbols:ATNHX7
tair10-symbols:ATSOS1tair10-symbols:SOS1TCDB:2.A.36.7.6TMHMM:TMhelix
UniGene:At.27246UniProt:M5BF34UniProt:Q9LKW9
Coordinates (TAIR10) chr2:+:457070..463145
Molecular Weight (calculated) 127196.00 Da
IEP (calculated) 7.83
GRAVY (calculated) 0.10
Length 1146 amino acids
Sequence (TAIR10)
(BLAST)
0001: MTTVIDATMA YRFLEEATDS SSSSSSSKLE SSPVDAVLFV GMSLVLGIAS RHLLRGTRVP YTVALLVIGI ALGSLEYGAK HNLGKIGHGI RIWNEIDPEL
0101: LLAVFLPALL FESSFSMEVH QIKRCLGQMV LLAVPGVLIS TACLGSLVKV TFPYEWDWKT SLLLGGLLSA TDPVAVVALL KELGASKKLS TIIEGESLMN
0201: DGTAIVVFQL FLKMAMGQNS DWSSIIKFLL KVALGAVGIG LAFGIASVIW LKFIFNDTVI EITLTIAVSY FAYYTAQEWA GASGVLTVMT LGMFYAAFAR
0301: TAFKGDSQKS LHHFWEMVAY IANTLIFILS GVVIAEGILD SDKIAYQGNS WRFLFLLYVY IQLSRVVVVG VLYPLLCRFG YGLDWKESII LVWSGLRGAV
0401: ALALSLSVKQ SSGNSHISKE TGTLFLFFTG GIVFLTLIVN GSTTQFVLRL LRMDILPAPK KRILEYTKYE MLNKALRAFQ DLGDDEELGP ADWPTVESYI
0501: SSLKGSEGEL VHHPHNGSKI GSLDPKSLKD IRMRFLNGVQ ATYWEMLDEG RISEVTANIL MQSVDEALDQ VSTTLCDWRG LKPHVNFPNY YNFLHSKVVP
0601: RKLVTYFAVE RLESACYISA AFLRAHTIAR QQLYDFLGES NIGSIVINES EKEGEEAKKF LEKVRSSFPQ VLRVVKTKQV TYSVLNHLLG YIENLEKVGL
0701: LEEKEIAHLH DAVQTGLKKL LRNPPIVKLP KLSDMITSHP LSVALPPAFC EPLKHSKKEP MKLRGVTLYK EGSKPTGVWL IFDGIVKWKS KILSNNHSLH
0801: PTFSHGSTLG LYEVLTGKPY LCDLITDSMV LCFFIDSEKI LSLQSDSTID DFLWQESALV LLKLLRPQIF ESVAMQELRA LVSTESSKLT TYVTGESIEI
0901: DCNSIGLLLE GFVKPVGIKE ELISSPAALS PSNGNQSFHN SSEASGIMRV SFSQQATQYI VETRARAIIF NIGAFGADRT LHRRPSSLTP PRSSSSDQLQ
1001: RSFRKEHRGL MSWPENIYAK QQQEINKTTL SLSERAMQLS IFGSMVNVYR RSVSFGGIYN NKLQDNLLYK KLPLNPAQGL VSAKSESSIV TKKQLETRKH
1101: ACQLPLKGES STRQNTMVES SDEEDEDEGI VVRIDSPSKI VFRNDL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)