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AT1G77300.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : histone methyltransferases(H3-K4 specific);histone methyltransferases(H3-K36 specific)
Curator
Summary (TAIR10)
Encodes a protein with histone lysine N-methyltransferase activity required specifically for the trimethylation of H3-K4 in FLC chromatin (and not in H3-K36 dimethylation). Acts as an inhibitor of flowering specifically involved in the autonomous promotion pathway. EFS also regulates the expression of genes involved in carotenoid biosynthesis.Modification of histone methylation at the CRTISO locus reduces transcript levels 90%. The increased shoot branching seen in some EFS mutants is likely due to the carotenoid biosynthesis defect having an effect on stringolactones.Required for ovule, embryo sac, anther and pollen development.
Computational
Description (TAIR10)
EARLY FLOWERING IN SHORT DAYS (EFS); FUNCTIONS IN: histone methyltransferase activity (H3-K4 specific); INVOLVED IN: in 10 processes; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: SET domain (InterPro:IPR001214), Post-SET domain (InterPro:IPR003616), AWS (InterPro:IPR006560), Zinc finger, CW-type (InterPro:IPR011124); BEST Arabidopsis thaliana protein match is: SET domain group 26 (TAIR:AT1G76710.2); Has 6189 Blast hits to 6025 proteins in 531 species: Archae - 3; Bacteria - 615; Metazoa - 2564; Fungi - 567; Plants - 1123; Viruses - 3; Other Eukaryotes - 1314 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G77300-MONOMERBioCyc:ARA:GQT-1195-MONOMERBioGrid:29285EC:2.1.1.43
eggNOG:COG2940eggNOG:KOG4442EMBL:AC004260EMBL:AK221916
EMBL:CP002684EMBL:DQ340869EMBL:EU014690EnsemblPlants:AT1G77300
EnsemblPlants:AT1G77300.1entrez:844066GeneID:844066GO:GO:0000775
GO:GO:0005634GO:GO:0008270GO:GO:0009553GO:GO:0009555
GO:GO:0009910GO:GO:0010223GO:GO:0010363GO:GO:0010452
GO:GO:0016116GO:GO:0018024GO:GO:0031062GO:GO:0040029
GO:GO:0042800GO:GO:0043067GO:GO:0048481GO:GO:0048653
GO:GO:0051568hmmpanther:PTHR22884hmmpanther:PTHR22884:SF276HOGENOM:HOG000029212
InParanoid:Q2LAE1IntAct:Q2LAE1InterPro:IPR001214InterPro:IPR003616
InterPro:IPR006560InterPro:IPR011124MINT:MINT-8049764OMA:KNESHEG
PaxDb:Q2LAE1PDB:2L7PPDBsum:2L7PPfam:PF00856
Pfam:PF07496Pfscan:PS50280Pfscan:PS50868Pfscan:PS51050
Pfscan:PS51215PhylomeDB:Q2LAE1PIR:T00458PRIDE:Q2LAE1
PRO:PR:Q2LAE1PROSITE:PS50280PROSITE:PS50868PROSITE:PS51050
PROSITE:PS51215ProteinModelPortal:Q2LAE1Proteomes:UP000006548RefSeq:NP_177854.6
SMART:SM00317SMART:SM00508SMART:SM00570SMR:Q2LAE1
STRING:3702.AT1G77300.1SUPFAM:SSF82199TAIR:AT1G77300tair10-symbols:ASHH2
tair10-symbols:CCR1tair10-symbols:EFStair10-symbols:LAZ2tair10-symbols:SDG8
UniGene:At.34505UniProt:A9QA57
Coordinates (TAIR10) chr1:-:29040160..29048810
Molecular Weight (calculated) 198862.00 Da
IEP (calculated) 5.48
GRAVY (calculated) -0.76
Length 1805 amino acids
Sequence (TAIR10)
(BLAST)
0001: MDCKENGVGD ASGCNIDANS LASNLAMNTN EDFYEKLSSR GQNLDSVSSL EIPQTASSVN HTIEGQRKCF TEIEQMGYGN SNSQEDAGNT DDDLYVCYNA
0101: DDTQEQGVVS GELEQSQELI CDTDLLVNCN KLDDGKESQD TNVSLVSIFS GSMQEKEAPQ AKEDEGYGGT TLPIGGSGID TESTFVNDAP EQFESLETTK
0201: HIKPDEVESD GISYRFDDGG KEGRNGPSSD LDTGSSDDIS LSQSFSFPDS LLDSSVFGCS ATESYLEDAI DIEGNGTIVV SPSLAITEML NNDDGGLCSH
0301: DLNKITVTET INPDLKLVRE DRLDTDLSVM NEKMLKNHVG DSSSESAVAA LSMNNGMAAD LRAENFSQSS PIDEKTLDME ANSPITDSSL IWNFPLNFGS
0401: GGIEVCNPEN AVEPLRIVDD NGRIGGEVAS ASGSDFCEAG MSSSRRKARD GKQCKVVQTK TSARHLRKSS RKKQSERDIE SIFKCSKQKR SSLLKTSRSS
0501: EWGLPSKTTE IFLQSNNIPY DGPPHHEPQR SQGNLNNGEH NRSSHNGNVE GSNRNIQASS GSCLRLKVKF GKSGGQNPLN ITVSKVSGNS LPGNGIVKAG
0601: TCLELPGSAH FGEDKMQTVE TKEDLVEKSN PVEKVSYLQS SDSMRDKKYN QDAGGLCRKV GGDVLDDDPH LSSIRMVEEC ERATGTQSLD AETSPDSEVI
0701: NSVPDSIVNI EHKEGLHHGF FSTPEDVVKK NRVLEKEDEL RASKSPSENG SHLIPNAKKA KHPKSKSNGT KKGKSKFSES AKDGRKNESH EGVEQRKSLN
0801: TSMGRDDSDY PEVGRIESHK TTGALLDADI GKTSATYGTI SSDVTHGEMV VDVTIEDSYS TESAWVRCDD CFKWRRIPAS VVGSIDESSR WICMNNSDKR
0901: FADCSKSQEM SNEEINEELG IGQDEADAYD CDAAKRGKEK EQKSKRLTGK QKACFKAIKT NQFLHRNRKS QTIDEIMVCH CKPSPDGRLG CGEECLNRML
1001: NIECLQGTCP AGDLCSNQQF QKRKYVKFER FQSGKKGYGL RLLEDVREGQ FLIEYVGEVL DMQSYETRQK EYAFKGQKHF YFMTLNGNEV IDAGAKGNLG
1101: RFINHSCEPN CRTEKWMVNG EICVGIFSMQ DLKKGQELTF DYNYVRVFGA AAKKCYCGSS HCRGYIGGDP LNGDVIIQSD SDEEYPELVI LDDDESGEGI
1201: LGATSRTFTD DADEQMPQSF EKVNGYKDLA PDNTQTQSSV SVKLPEREIP PPLLQPTEVL KELSSGISIT AVQQEVPAEK KTKSTSPTSS SLSRMSPGGT
1301: NSDKTTKHGS GEDKKILPRP RPRMKTSRSS ESSKRDKGGI YPGVNKAQVI PVNKLQQQPI KSKGSEKVSP SIETFEGKLN ELLDAVGGIS KRRDSAKGYL
1401: KLLLLTAASR GTDEEGIYSN RDLSMILDAL LKTKSKSVLV DIINKNGLQM LHNIMKQYRG DFKRIPIIRK LLKVLEYLAT RKILALEHII RRPPFAGMES
1501: FKDSVLSFTE HDDYTVHNIA RSFRDRWIPK HFRKPWRINR EERSESMRSP INRRFRASQE PRYDHQSPRP AEPAASVTSS KAATPETASV SEGYSEPNSG
1601: LPETNGRKRK SRWDQPSKTK EQRIMTILSQ QTDETNGNQD VQDDLPPGFS SPCTDVPDAI TAQPQQKFLS RLPVSYGIPL SIVHQFGSPG KEDPTTWSVA
1701: PGMPFYPFPP LPPVSHGEFF AKRNVRACSS SMGNLTYSNE ILPATPVTDS TAPTRKRELF SSDIGTTYFR QQKQSVPPWL RNNGGEKTAN SPIPGNLTLE
1801: KKLNS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)