AT1G76490.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:endoplasmic reticulum 0.991 What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : hydroxy methylglutaryl CoA reductase 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes a 3-hydroxy-3-methylglutaryl coenzyme A reductase, which is involved in melavonate biosynthesis and performs the first committed step in isoprenoid biosynthesis. Expression is activated in dark in leaf tissue but not controlled by light in the root (confine | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
hydroxy methylglutaryl CoA reductase 1 (HMG1); CONTAINS InterPro DOMAIN/s: Hydroxymethylglutaryl-CoA reductase, class I, catalytic (InterPro:IPR004554), Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding (InterPro:IPR009029), Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding (InterPro:IPR009023), Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic (InterPro:IPR002202); BEST Arabidopsis thaliana protein match is: 3-hydroxy-3-methylglutaryl-CoA reductase 2 (TAIR:AT2G17370.1); Has 2212 Blast hits to 2210 proteins in 935 species: Archae - 202; Bacteria - 1018; Metazoa - 225; Fungi - 225; Plants - 266; Viruses - 1; Other Eukaryotes - 275 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr1:+:28695801..28698206 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 69284.20 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 7.59 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.01 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 642 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MKKKQAGPQQ TCEFVSYKTL LISPSHLSRH LTTSLLSPLS PPWRDYSFPP MDLRRRPPKP PVTNNNNSNG SFRSYQPRTS DDDHRRRATT IAPPPKASDA 101: LPLPLYLTNA VFFTLFFSVA YYLLHRWRDK IRYNTPLHVV TITELGAIIA LIASFIYLLG FFGIDFVQSF ISRASGDAWD LADTIDDDDH RLVTCSPPTP 201: IVSVAKLPNP EPIVTESLPE EDEEIVKSVI DGVIPSYSLE SRLGDCKRAA SIRREALQRV TGRSIEGLPL DGFDYESILG QCCEMPVGYI QIPVGIAGPL 301: LLDGYEYSVP MATTEGCLVA STNRGCKAMF ISGGATSTVL KDGMTRAPVV RFASARRASE LKFFLENPEN FDTLAVVFNR SSRFARLQSV KCTIAGKNAY 401: VRFCCSTGDA MGMNMVSKGV QNVLEYLTDD FPDMDVIGIS GNFCSDKKPA AVNWIEGRGK SVVCEAVIRG EIVNKVLKTS VAALVELNML KNLAGSAVAG 501: SLGGFNAHAS NIVSAVFIAT GQDPAQNVES SQCITMMEAI NDGKDIHISV TMPSIEVGTV GGGTQLASQS ACLNLLGVKG ASTESPGMNA RRLATIVAGA 601: VLAGELSLMS AIAAGQLVRS HMKYNRSSRD ISGATTTTTT TT |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)