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AT3G48780.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
endoplasmic reticulum 0.981
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : serine palmitoyltransferase 1
Curator
Summary (TAIR10)
Encodes one of the two LCB2 subunits (LCB2a and LCB2b) of serine palmitoyltransferase, an enzyme involved in sphingolipid biosynthesis. LCB2a and LCB2b are functional redundant. Double mutants are gametophytic lethal.
Computational
Description (TAIR10)
serine palmitoyltransferase 1 (SPT1); FUNCTIONS IN: serine C-palmitoyltransferase activity; INVOLVED IN: photomorphogenesis, sphingolipid biosynthetic process, pollen development; LOCATED IN: endomembrane system; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferase, class I/classII (InterPro:IPR004839), Aminotransferase, class-II, pyridoxal-phosphate binding site (InterPro:IPR001917), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: long chain base2 (TAIR:AT5G23670.2); Has 10415 Blast hits to 10387 proteins in 2165 species: Archae - 77; Bacteria - 7001; Metazoa - 736; Fungi - 585; Plants - 234; Viruses - 9; Other Eukaryotes - 1773 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G48780-MONOMEREC:2.3.1.50eggNOG:COG0156eggNOG:KOG1357
EMBL:AB074928EMBL:AK229667EMBL:AL132963EMBL:AY054489
EMBL:AY059882EMBL:AY114662EMBL:BT006615EMBL:CP002686
EnsemblPlants:AT3G48780EnsemblPlants:AT3G48780.1entrez:824039Gene3D:3.40.640.10
Gene3D:3.90.1150.10GeneID:824039Genevisible:Q9M304GO:GO:0004758
GO:GO:0005789GO:GO:0009555GO:GO:0009640GO:GO:0016021
GO:GO:0030148GO:GO:0030170Gramene:AT3G48780.1gramene_pathway:2.3.1.50
gramene_pathway:PWY-5129hmmpanther:PTHR13693hmmpanther:PTHR13693:SF62HOGENOM:HOG000206826
InParanoid:Q9M304InterPro:IPR001917InterPro:IPR004839InterPro:IPR015421
InterPro:IPR015422InterPro:IPR015424KEGG:ath:AT3G48780KO:K00654
OMA:PFFRVHEPaxDb:Q9M304Pfam:PF00155Pfam:Q9M304
PhylomeDB:Q9M304PIR:T49274PRIDE:Q9M304PRO:PR:Q9M304
PROSITE:PS00599ProteinModelPortal:Q9M304Proteomes:UP000006548Reactome:R-ATH-1660661
RefSeq:NP_190447.1scanprosite:PS00599SMR:Q9M304STRING:3702.AT3G48780.1
SUPFAM:SSF53383TAIR:AT3G48780tair10-symbols:ATSPT1tair10-symbols:SPT1
UniGene:At.1379UniGene:At.75040UniPathway:UPA00222UniProt:Q9M304
Coordinates (TAIR10) chr3:+:18089346..18092276
Molecular Weight (calculated) 53866.00 Da
IEP (calculated) 8.55
GRAVY (calculated) -0.05
Length 489 amino acids
Sequence (TAIR10)
(BLAST)
001: MITIPYLTAV STYFSYGLLF AFGQLRDYSR LIFDWWRTNN LQGYAPICLA HEDFYIRRLY HRIQDCFGRP ISSAPDAWID VVERVSDDNN KTLKRTTKTS
101: RCLNLGSYNY LGFGSFDEYC TPRVIESLKK FSASTCSSRV DAGTTSVHAE LEDCVAKYVG QPAAVIFGMG YATNSAIIPV LIGKGGLIIS DSLNHTSIVN
201: GARGSGATIR VFQHNTPGHL EKVLKEQIAE GQPRTHRPWK KIIVVVEGIY SMEGEICHLP EIVSICKKYK AYVYLDEAHS IGAIGKTGRG VCELLGVDTS
301: DVDIMMGTFT KSFGSCGGYI AGSKDLIQYL KHQCPAHLYA TSISTPSATQ IISAIKVILG EDGSNRGAQK LARIRENSNF FRAELQKMGF EVLGDNDSPV
401: MPIMLYNPAK IPAFSRECLR ENLAVVVVGF PATPLLLARA RICISASHSR EDLIKALQVI SKAGDLTGIK YFPAAPKKQE VEKNGIKLD
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)