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AT1G48410.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:29104584 (2017): nucleus nuclear matrix nucleolus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:19334764 (2009): plasma membrane
  • PMID:18433157 (2008): cytosol
  • PMID:18433157 (2008): nucleus
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Stabilizer of iron transporter SufD / Polynucleotidyl transferase
Curator
Summary (TAIR10)
Encodes an RNA Slicer that selectively recruits microRNAs and siRNAs. There is currently no evidence that AGO1 Slicer is in a high molecular weight RNA-induced silencing complex (RISC). Mutants are defective in post-transcriptional gene silencing and have pleiotropic developmental and morphological defects. Through its action on the regulation of ARF17 expression, the protein regulates genes involved at the cross talk between auxin and light signaling during adventitious root development. AGO1 seems to be targeted for degradation by silencing suppressor F-box-containing proteins from Turnip yellow virus and Cucurbit aphid-borne yellow virus.
Computational
Description (TAIR10)
ARGONAUTE 1 (AGO1); FUNCTIONS IN: protein binding, endoribonuclease activity, siRNA binding, miRNA binding; INVOLVED IN: in 11 processes; LOCATED IN: cytosol, nucleus, cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Domain of unknown function DUF1785 (InterPro:IPR014811), Stem cell self-renewal protein Piwi (InterPro:IPR003165), Argonaute/Dicer protein, PAZ (InterPro:IPR003100), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337); BEST Arabidopsis thaliana protein match is: Stabilizer of iron transporter SufD / Polynucleotidyl transferase (TAIR:AT5G43810.2); Has 29249 Blast hits to 15917 proteins in 1190 species: Archae - 22; Bacteria - 5845; Metazoa - 12576; Fungi - 2412; Plants - 4639; Viruses - 404; Other Eukaryotes - 3351 (source: NCBI BLink).
Protein Annotations
BioGrid:26487eggNOG:ENOG410XP07eggNOG:KOG1041EMBL:AC007932
EMBL:AC020889EMBL:AK227868EMBL:BT000941EMBL:CP002684
EMBL:U91995EnsemblPlants:AT1G48410EnsemblPlants:AT1G48410.1entrez:841262
ExpressionAtlas:O04379Gene3D:3.30.420.10GeneID:841262Genevisible:O04379
GO:GO:0003723GO:GO:0004521GO:GO:0005634GO:GO:0005737
GO:GO:0005829GO:GO:0006351GO:GO:0006355GO:GO:0006417
GO:GO:0007275GO:GO:0009616GO:GO:0009733GO:GO:0009850
GO:GO:0009955GO:GO:0009965GO:GO:0010218GO:GO:0010305
GO:GO:0010589GO:GO:0016032GO:GO:0016246GO:GO:0016441
GO:GO:0019898GO:GO:0030529GO:GO:0031047GO:GO:0035195
GO:GO:0045087GO:GO:0046872GO:GO:0048830GO:GO:0048864
GO:GO:0060145GO:GO:0090502hmmpanther:PTHR22891hmmpanther:PTHR22891:SF34
HOGENOM:HOG000116043InParanoid:O04379IntAct:O04379InterPro:IPR003100
InterPro:IPR003165InterPro:IPR012337InterPro:IPR014811InterPro:IPR024357
InterPro:IPR032472InterPro:IPR032473InterPro:IPR032474iPTMnet:O04379
KEGG:ath:AT1G48410KO:K11593OMA:CHRRETPPaxDb:O04379
PDB:3VNAPDB:3VNBPDB:4G0PPDB:4G0Q
PDB:4G0XPDB:4G0YPDB:4G0ZPDBsum:3VNA
PDBsum:3VNBPDBsum:4G0PPDBsum:4G0QPDBsum:4G0X
PDBsum:4G0YPDBsum:4G0ZPfam:O04379Pfam:PF02170
Pfam:PF02171Pfam:PF08699Pfam:PF12764Pfam:PF16486
Pfam:PF16487Pfam:PF16488Pfscan:PS50821Pfscan:PS50822
PhylomeDB:O04379PRIDE:O04379PRO:PR:O04379PROSITE:PS50821
PROSITE:PS50822ProteinModelPortal:O04379Proteomes:UP000006548Reactome:R-ATH-426486
Reactome:R-ATH-426496Reactome:R-ATH-5578749RefSeq:NP_001185169.1RefSeq:NP_175274.1
RefSeq:NP_849784.1SMART:SM00949SMART:SM00950SMART:SM01163
SMR:O04379STRING:3702.AT1G48410.2SUPFAM:SSF101690SUPFAM:SSF53098
TAIR:AT1G48410tair10-symbols:AGO1UniGene:At.21124UniProt:O04379
Coordinates (TAIR10) chr1:-:17886285..17891892
Molecular Weight (calculated) 116198.00 Da
IEP (calculated) 9.65
GRAVY (calculated) -0.51
Length 1048 amino acids
Sequence (TAIR10)
(BLAST)
0001: MVRKRRTDAP SEGGEGSGSR EAGPVSGGGR GSQRGGFQQG GGQHQGGRGY TPQPQQGGRG GRGYGQPPQQ QQQYGGPQEY QGRGRGGPPH QGGRGGYGGG
0101: RGGGPSSGPP QRQSVPELHQ ATSPTYQAVS SQPTLSEVSP TQVPEPTVLA QQFEQLSVEQ GAPSQAIQPI PSSSKAFKFP MRPGKGQSGK RCIVKANHFF
0201: AELPDKDLHH YDVTITPEVT SRGVNRAVMK QLVDNYRDSH LGSRLPAYDG RKSLYTAGPL PFNSKEFRIN LLDEEVGAGG QRREREFKVV IKLVARADLH
0301: HLGMFLEGKQ SDAPQEALQV LDIVLRELPT SRYIPVGRSF YSPDIGKKQS LGDGLESWRG FYQSIRPTQM GLSLNIDMSS TAFIEANPVI QFVCDLLNRD
0401: ISSRPLSDAD RVKIKKALRG VKVEVTHRGN MRRKYRISGL TAVATRELTF PVDERNTQKS VVEYFHETYG FRIQHTQLPC LQVGNSNRPN YLPMEVCKIV
0501: EGQRYSKRLN ERQITALLKV TCQRPIDREK DILQTVQLND YAKDNYAQEF GIKISTSLAS VEARILPPPW LKYHESGREG TCLPQVGQWN MMNKKMINGG
0601: TVNNWICINF SRQVQDNLAR TFCQELAQMC YVSGMAFNPE PVLPPVSARP EQVEKVLKTR YHDATSKLSQ GKEIDLLIVI LPDNNGSLYG DLKRICETEL
0701: GIVSQCCLTK HVFKMSKQYM ANVALKINVK VGGRNTVLVD ALSRRIPLVS DRPTIIFGAD VTHPHPGEDS SPSIAAVVAS QDWPEITKYA GLVCAQAHRQ
0801: ELIQDLFKEW KDPQKGVVTG GMIKELLIAF RRSTGHKPLR IIFYRDGVSE GQFYQVLLYE LDAIRKACAS LEAGYQPPVT FVVVQKRHHT RLFAQNHNDR
0901: HSVDRSGNIL PGTVVDSKIC HPTEFDFYLC SHAGIQGTSR PAHYHVLWDE NNFTADGLQS LTNNLCYTYA RCTRSVSIVP PAYYAHLAAF RARFYMEPET
1001: SDSGSMASGS MARGGGMAGR STRGPNVNAA VRPLPALKEN VKRVMFYC
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)