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AT1G19350.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Brassinosteroid signalling positive regulator (BZR1) family protein
Curator
Summary (TAIR10)
Encodes brassinosteroid (BR) signalling protein that accumulates in the nucleus as dephosphorylated form in response to BRs. Is phosphorylated by the BIN2 GSK3 kinase. It synergistically interacts with BIM1 to bind to E box sequences (CANNTG). The protein contains a nuclear localization signal (NLS), followed by a highly conserved amino-terminal domain (N) shared by all family members, a BIN2 phosphorylation domain (P), a PEST motif, involved in protein degradation in the absence of BR, and a carboxyl-terminal domain. BES1 can interact with the ELF6 and REF6 Jumonji N/C-domain containing proteins and may direct them to modify histone methylation upstream of some brassinosteroid responsive-genes
Computational
Description (TAIR10)
BRI1-EMS-SUPPRESSOR 1 (BES1); CONTAINS InterPro DOMAIN/s: BZR1, transcriptional repressor (InterPro:IPR008540); BEST Arabidopsis thaliana protein match is: Brassinosteroid signalling positive regulator (BZR1) family protein (TAIR:AT1G75080.2); Has 2916 Blast hits to 477 proteins in 80 species: Archae - 0; Bacteria - 14; Metazoa - 122; Fungi - 71; Plants - 275; Viruses - 0; Other Eukaryotes - 2434 (source: NCBI BLink).
Protein Annotations
BioGrid:23757DIP:DIP-34780NeggNOG:ENOG410IGXVeggNOG:ENOG410YC62
EMBL:AC025808EMBL:AF134217EMBL:AF372937EMBL:AY065041
EMBL:AY074829EMBL:AY086340EMBL:BK000396EMBL:CP002684
EnsemblPlants:AT1G19350EnsemblPlants:AT1G19350.1EnsemblPlants:AT1G19350.4EnsemblPlants:AT1G19350.5
EnsemblPlants:AT1G19350.6entrez:838518ExpressionAtlas:Q9LN63GeneID:838518
Genevisible:Q9LN63GO:GO:0003677GO:GO:0005634GO:GO:0005737
GO:GO:0006351GO:GO:0006355GO:GO:0009742hmmpanther:PTHR31506
hmmpanther:PTHR31506:SF6HOGENOM:HOG000238930InParanoid:Q9LN63IntAct:Q9LN63
InterPro:IPR008540InterPro:IPR033264iPTMnet:Q9LN63KEGG:ath:AT1G19350
KO:K14503PANTHER:PTHR31506PaxDb:Q9LN63Pfam:PF05687
Pfam:Q9LN63PhylomeDB:Q9LN63PIR:G86326PRIDE:Q9LN63
PRO:PR:Q9LN63ProteinModelPortal:Q9LN63Proteomes:UP000006548RefSeq:NP_001077562.1
RefSeq:NP_564081.1RefSeq:NP_973864.1RefSeq:NP_973865.1STRING:3702.AT1G19350.3
TAIR:AT1G19350tair10-symbols:BES1tair10-symbols:BZR2UniGene:At.24276
UniProt:Q9LN63
Coordinates (TAIR10) chr1:+:6688841..6690165
Molecular Weight (calculated) 36487.40 Da
IEP (calculated) 9.56
GRAVY (calculated) -0.67
Length 335 amino acids
Sequence (TAIR10)
(BLAST)
001: MTSDGATSTS AAAAAAAMAT RRKPSWRERE NNRRRERRRR AVAAKIYTGL RAQGNYNLPK HCDNNEVLKA LCSEAGWVVE EDGTTYRKGH KPLPGDMAGS
101: SSRATPYSSH NQSPLSSTFD SPILSYQVSP SSSSFPSPSR VGDPHNISTI FPFLRNGGIP SSLPPLRISN SAPVTPPVSS PTSRNPKPLP TWESFTKQSM
201: SMAAKQSMTS LNYPFYAVSA PASPTHHRQF HAPATIPECD ESDSSTVDSG HWISFQKFAQ QQPFSASMVP TSPTFNLVKP APQQLSPNTA AIQEIGQSSE
301: FKFENSQVKP WEGERIHDVA MEDLELTLGN GKAHS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)