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AT1G09430.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26781341 (2016): plasma membrane
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:25641898 (2015): plasma membrane
  • PMID:21531424 (2011): plastid
  • PMID:21166475 (2011): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : ATP-citrate lyase A-3
Curator
Summary (TAIR10)
Encodes subunit A of the heteromeric enzyme ATP citrate lyase (ACL). In animals, ACL is encoded by a single gene; ACL in Arabidopsis is composed of two polypeptides, ACLA (encoded by 3 genes) and ACLB (encoded by 2 genes). The holoenzyme has an A(4)B(4)stoichiometry. Expression of both ACLA and ACLB but not of either of the subunits alone results in ACL activity.
Computational
Description (TAIR10)
ATP-citrate lyase A-3 (ACLA-3); CONTAINS InterPro DOMAIN/s: ATP-grasp fold, subdomain 2 (InterPro:IPR013816), ATP-grasp fold, succinyl-CoA synthetase-type (InterPro:IPR013650), Succinyl-CoA synthetase-like (InterPro:IPR016102); BEST Arabidopsis thaliana protein match is: ATP-citrate lyase A-1 (TAIR:AT1G10670.4); Has 5303 Blast hits to 5302 proteins in 1635 species: Archae - 133; Bacteria - 3235; Metazoa - 230; Fungi - 139; Plants - 96; Viruses - 0; Other Eukaryotes - 1470 (source: NCBI BLink).
Protein Annotations
BioGrid:22707EC:2.3.3.8eggNOG:COG0045eggNOG:KOG1254
EMBL:AC003970EMBL:AY127019EMBL:BT003017EMBL:CP002684
EnsemblPlants:AT1G09430EnsemblPlants:AT1G09430.1entrez:837466Gene3D:3.30.470.20
Gene3D:3.40.50.261GeneID:837466Genevisible:O80526GO:GO:0003878
GO:GO:0005524GO:GO:0005829GO:GO:0006085GO:GO:0006629
GO:GO:0009346Gramene:AT1G09430.1gramene_pathway:2.3.3.8gramene_pathway:PWY-5172
hmmpanther:PTHR23118HOGENOM:HOG000151490InParanoid:O80526IntAct:O80526
InterPro:IPR013650InterPro:IPR013816InterPro:IPR016102InterPro:IPR032263
iPTMnet:O80526KEGG:00020+2.3.3.8KEGG:00020+6.2.1.5KEGG:00640+6.2.1.5
KEGG:00660+6.2.1.5KEGG:00720+2.3.3.8KEGG:00720+6.2.1.5KEGG:ath:AT1G09430
KO:K01648OMA:GIHIEENPaxDb:O80526Pfam:O80526
Pfam:PF08442Pfam:PF16114PhylomeDB:O80526PIR:F86227
PRIDE:O80526PRO:PR:O80526ProteinModelPortal:O80526Proteomes:UP000006548
RefSeq:NP_172414.1SMR:O80526STRING:3702.AT1G09430.1SUPFAM:SSF52210
SUPFAM:SSF56059TAIR:AT1G09430tair10-symbols:ACLA-3UniGene:At.23527
UniGene:At.66837unipathway:UPA00223UniProt:O80526
Coordinates (TAIR10) chr1:+:3042135..3044978
Molecular Weight (calculated) 46948.60 Da
IEP (calculated) 4.90
GRAVY (calculated) -0.10
Length 424 amino acids
Sequence (TAIR10)
(BLAST)
001: MARKKIREYD SKRLLKEHLK RLANIDLQIR SAQVTESTDF TELTNQESWL SSTKLVVKPD MLFGKRGKSG LVALKLDLAE VADFVKARLG TEVEMEGCKA
101: PITTFIVEPF VPHDQEYYLS IVSDRLGCTI SFSECGGIEI EENWDKVKTI FLPAEKSMTL EVCAPLIATL PLEVRAKIGN FIMGAFAVFQ DLDFSFMEMN
201: PFTLVDGEPF PLDMRGELDD TAAFKNFNKW GDIEFPLPFG RVLSSTENFI HGLDEKTSAS LKFTVLNPKG RIWTMVAGGG ASVIYADTVG DLGYASELGN
301: YAEYSGAPNE EEVLQYARVV IDCATTDPDG RKRALLIGGG IANFTDVAAT FNGIIRALRE KETRLKASRM HIYVRRGGPN YQTGLARMRA LGEELGVPLE
401: VYGPEATMTG ICKRAIDCIM LPDA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)