AT5G24630.5
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : double-stranded DNA binding | ||||||||||||||||||||||||
| Curator Summary (TAIR10) |
This gene is predicted to encode a protein that forms part of the topoisomerase VI complex. BIN4 is a nuclear-localized protein that can bind DNA. bin4 mutants are brassinolide-insensitive dwarves with severely reduced cell size in leaves, roots, and hypocotyls. Proper development of root hairs and trichomes is also disrupted in bin4 mutants and they have elevated levels of double strand breaks in their cotyledon cells. | ||||||||||||||||||||||||
| Computational Description (TAIR10) |
brassinosteroid-insensitive4 (BIN4); FUNCTIONS IN: double-stranded DNA binding; INVOLVED IN: in 7 processes; LOCATED IN: DNA topoisomerase complex (ATP-hydrolyzing), nucleus; EXPRESSED IN: cotyledon vascular system, cotyledon, root tip, leaf trichome, leaf; Has 2167 Blast hits to 1734 proteins in 263 species: Archae - 6; Bacteria - 177; Metazoa - 877; Fungi - 312; Plants - 129; Viruses - 12; Other Eukaryotes - 654 (source: NCBI BLink). | ||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:-:8432523..8435682 | ||||||||||||||||||||||||
| Molecular Weight (calculated) | 48624.60 Da | ||||||||||||||||||||||||
| IEP (calculated) | 4.92 | ||||||||||||||||||||||||
| GRAVY (calculated) | -0.86 | ||||||||||||||||||||||||
| Length | 446 amino acids | ||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MSSSSREGSP DWLRSYEAPM TTSLLSLSSS DDDSPYRESE VISSLPLPDD DGDDIVVLET ESVELLTRKN SETKVVTKQV SIEQVFSRKK KADASLNLEG 101: KENGNNVDCE KLSSKHKDAQ GGADSVWLVS SDSEPSSPIK QEVTVSTEKD ADFVLEATEE EPAVKTVRKE KSPKTKSKSS RKTPKEGNSA QEILKTEDKD 201: TDTTIAEQVT PEKSPKTKSK SSRKTPKEEN CAQEILKTED TDTDTIIAEE VTTDQKIKPS SGSSSRLPLV LSEKVNRTKV LVECEGDSID LSGDMGAVGR 301: VVVSDTTGDM YLDLKGTIYK STIIPSRTFC VVNVGQTEAK IEAIMNDFIQ LIPQSNVYEA ETMVEGTLEG FTFESDDESN KNAKTAVKPA DQSVGTEEET 401: NTKAKPKAKA KGETVIGKKR GRPSKEKQPP AKKARNSAPK KPKAKK |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)